Spry1 Is Expressed in Hemangioblasts and Negatively Regulates Primitive Hematopoiesis and Endothelial Cell Function

The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells

(2010) Yuefeng Tang et al.   GENESIS

Sprouty1 inhibits angiogenesis in association with up-regulation of p21 and p27

(2010) Sangjin Lee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

(2010) Jean-Charles Boisset et al.   NATURE

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

(2010) Karima Kissa et al.   NATURE

Haematopoietic stem cells derive directly from aortic endothelium during development

(2010) Julien Y. Bertrand et al.   NATURE

Intermolecular Interactions of Sprouty Proteins and Their Implications in Development and Disease

(2009) F. Edwin et al.   MOLECULAR PHARMACOLOGY

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

(2009) Christophe Lancrin et al.   NATURE

Regulation of ERK activity duration by Sprouty contributes to dorsoventral patterning

(2009) Hiroshi Hanafusa et al.   NATURE CELL BIOLOGY

Suppression of Sproutys Has a Therapeutic Effect for a Mouse Model of Ischemia by Enhancing Angiogenesis

(2009) Koji Taniguchi et al.   PLoS One

Sprouty proteins, masterminds of receptor tyrosine kinase signaling

(2008) Miguel A. Cabrita et al.   ANGIOGENESIS

The endothelial antigen ESAM marks primitive hematopoietic progenitors throughout life in mice

(2008) T. Yokota et al.   BLOOD

Both primitive and definitive blood cells are derived from Flk-1+ mesoderm

(2008) J. J. Lugus et al.   BLOOD

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

(2008) Ann C. Zovein et al.   Cell Stem Cell

The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF

(2008) S. Pearson et al.   DEVELOPMENT

c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo

(2008) C. He et al.   DEVELOPMENT

Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia

(2008) Xuehui Yang et al.   DEVELOPMENTAL BIOLOGY