Characterization of a Drosophila Alzheimer's Disease Model: Pharmacological Rescue of Cognitive Defects

2010 Alzheimer's disease facts and figures

(2010)   Alzheimers & Dementia

Tau Ser262 phosphorylation is critical for A 42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease

(2010) K. Iijima et al.   HUMAN MOLECULAR GENETICS

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

Transgenic Drosophila models of Alzheimer’s disease and tauopathies

(2009) Kanae Iijima-Ando et al.   Brain Structure & Function

Aβ exacerbates the neuronal dysfunction caused by human tau expression in a Drosophila model of Alzheimer's disease

(2009) James Folwell et al.   EXPERIMENTAL NEUROLOGY

Distinctive roles of different β-amyloid 42 aggregates in modulation of synaptic functions

(2009) Hsueh-Cheng Chiang et al.   FASEB JOURNAL

Drosophila melanogaster as a Model Organism of Brain Diseases

(2009) Astrid Jeibmann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Apolipoprotein E-Mimetics Inhibit Neurodegeneration and Restore Cognitive Functions in a Transgenic Drosophila Model of Alzheimer's Disease

(2009) Svetlana Sarantseva et al.   PLoS One

Mitochondrial Mislocalization Underlies Aβ42-Induced Neuronal Dysfunction in a Drosophila Model of Alzheimer's Disease

(2009) Kanae Iijima-Ando et al.   PLoS One

Identification of Novel Genes That Modify Phenotypes Induced by Alzheimer's  -Amyloid Overexpression in Drosophila

(2008) W. Cao et al.   GENETICS

Amyloid precursor protein-induced axonopathies are independent of amyloid-β peptides

(2008) Gorazd B. Stokin et al.   HUMAN MOLECULAR GENETICS

Overexpression of Neprilysin Reduces Alzheimer Amyloid-β42 (Aβ42)-induced Neuron Loss and Intraneuronal Aβ42 Deposits but Causes a Reduction in cAMP-responsive Element-binding Protein-mediated Transcription, Age-dependent Axon Pathology, and Premature Death inDrosophila

(2008) Kanae Iijima-Ando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

(2008) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neurotoxic effects induced by the Drosophila amyloid-β peptide suggest a conserved toxic function

(2008) Katia Carmine-Simmen et al.   NEUROBIOLOGY OF DISEASE

Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system

(2008) Jennifer L. Hanslick et al.   NEUROBIOLOGY OF DISEASE

Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila

(2008) Koichi Iijima et al.   PLoS One