Probenecid Inhibits the Human Bitter Taste Receptor TAS2R16 and Suppresses Bitter Perception of Salicin

Allelic Variation in TAS2R Bitter Receptor Genes Associates with Variation in Sensations from and Ingestive Behaviors toward Common Bitter Beverages in Adults

(2010) John E. Hayes et al.   CHEMICAL SENSES

Modulation of Bitter Taste Perception by a Small Molecule hTAS2R Antagonist

(2010) Jay P. Slack et al.   CURRENT BIOLOGY

Characterization of the β-d-Glucopyranoside Binding Site of the Human Bitter Taste Receptor hTAS2R16

(2010) Takanobu Sakurai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

(2010) Deepak A Deshpande et al.   NATURE MEDICINE

Insights into the Binding of Phenyltiocarbamide (PTC) Agonist to Its Target Human TAS2R38 Bitter Receptor

(2010) Xevi Biarnés et al.   PLoS One

Structural requirements of bitter taste receptor activation

(2010) A. Brockhoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals

(2010) M. Tizzano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

(2009) Wolfgang Meyerhof et al.   CHEMICAL SENSES

Cell-to-cell communication in intact taste buds through ATP signalling from pannexin 1 gap junction hemichannels

(2009) Robin Dando et al.   JOURNAL OF PHYSIOLOGY-LONDON

Atomic-Level Mapping of Antibody Epitopes on a GPCR

(2009) Cheryl Paes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

Motile Cilia of Human Airway Epithelia Are Chemosensory

(2009) A. S. Shah et al.   SCIENCE

Probenecid, a gout remedy, inhibits pannexin 1 channels

(2008) William Silverman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Pharmacokinetic and Pharmacodynamic Interaction between Allopurinol and Probenecid??in Healthy Subjects

(2008) Sophie L Stocker et al.   CLINICAL PHARMACOKINETICS

Taste Cells of the Gut and Gastrointestinal Chemosensation

(2008) J. M. Egan et al.   MOLECULAR INTERVENTIONS

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

(2008) P. Jeffrey Conn et al.   NATURE REVIEWS DRUG DISCOVERY

Bitter Taste Receptors Influence Glucose Homeostasis

(2008) Cedrick D. Dotson et al.   PLoS One