Design, Synthesis, and Characterization of a Highly Effective Hog1 Inhibitor: A Powerful Tool for Analyzing MAP Kinase Signaling in Yeast

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Multilayered control of gene expression by stress-activated protein kinases

(2009) Eulàlia de Nadal et al.   EMBO JOURNAL

Control of high osmolarity signalling in the yeast Saccharomyces cerevisiae

(2009) Stefan Hohmann   FEBS LETTERS

Selective p38α Inhibitors Clinically Evaluated for the Treatment of Chronic Inflammatory Disorders

(2009) David M. Goldstein et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Stress-activated Protein Kinase Hog1 Mediates S Phase Delay in Response to Osmostress

(2009) Gilad Yaakov et al.   MOLECULAR BIOLOGY OF THE CELL

Robustness and fragility in the yeast high osmolarity glycerol (HOG) signal-transduction pathway

(2009) Marcus Krantz et al.   Molecular Systems Biology

Dynamic Signaling in the Hog1 MAPK Pathway Relies on High Basal Signal Transduction

(2009) J. Macia et al.   Science Signaling

Mitogen-Activated Protein Kinase Hog1 Mediates Adaptation to G1Checkpoint Arrest during Arsenite and Hyperosmotic Stress

(2008) Iwona Migdal et al.   EUKARYOTIC CELL

High-throughput kinase profiling as a platform for drug discovery

(2008) David M. Goldstein et al.   NATURE REVIEWS DRUG DISCOVERY

Short cut to 1,2,3-triazole-based p38 MAP kinase inhibitorsvia [3+2]-cycloaddition chemistry

(2008) Peter Dinér et al.   NEW JOURNAL OF CHEMISTRY

Stress resistance and signal fidelity independent of nuclear MAPK function

(2008) P. J. Westfall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast

(2008) Elke Ericson et al.   PLoS Genetics