Role of Mitochondrial Electron Transport Chain Complexes in Capsaicin Mediated Oxidative Stress Leading to Apoptosis in Pancreatic Cancer Cells

Pancreatic Tumor Suppression by Benzyl Isothiocyanate Is Associated with Inhibition of PI3K/AKT/FOXO Pathway

(2011) S. R. Boreddy et al.   CLINICAL CANCER RESEARCH

Activation of Checkpoint Kinase 2 by 3,3'-Diindolylmethane Is Required for Causing G2/M Cell Cycle Arrest in Human Ovarian Cancer Cells

(2010) P. K. Kandala et al.   MOLECULAR PHARMACOLOGY

Mitochondrial Complex III Defects Contribute to Inefficient Respiration and ATP Synthesis in the Myocardium of Trypanosoma cruzi–Infected Mice

(2009) Jian-Jun Wen et al.   ANTIOXIDANTS & REDOX SIGNALING

Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells

(2009) Ravi P. Sahu et al.   CARCINOGENESIS

The Role of STAT-3 in the Induction of Apoptosis in Pancreatic Cancer Cells by Benzyl Isothiocyanate

(2009) R. P. Sahu et al.   JNCI-Journal of the National Cancer Institute

Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway

(2009) N H Thoennissen et al.   ONCOGENE

In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway

(2008) Ruifen Zhang et al.   APOPTOSIS

Mitochondrial drugs

(2008) Peter L Toogood   CURRENT OPINION IN CHEMICAL BIOLOGY

Benzyl Isothiocyanate Targets Mitochondrial Respiratory Chain to Trigger Reactive Oxygen Species-dependent Apoptosis in Human Breast Cancer Cells

(2008) Dong Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL