HIV-1 gp41 Core with Exposed Membrane-Proximal External Region Inducing Broad HIV-1 Neutralizing Antibodies

3-Hydroxyphthalic Anhydride-Modified Chicken Ovalbumin Exhibits Potent and Broad Anti-HIV-1 Activity: a Potential Microbicide for Preventing Sexual Transmission of HIV-1

(2010) L. Li et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structural Characterization of HIV gp41 with the Membrane-proximal External Region

(2010) Wuxian Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a gp41 Core-Binding Molecule with Homologous Sequence of Human TNNI3K-Like Protein as a Novel Human Immunodeficiency Virus Type 1 Entry Inhibitor

(2010) Y. Zhu et al.   JOURNAL OF VIROLOGY

Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution

(2010) X. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions

(2010) E. M. Scherer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maleic anhydride-modified chicken ovalbumin as an effective and inexpensive anti-HIV microbicide candidate for prevention of HIV sexual transmission

(2010) Lin Li et al.   Retrovirology

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

(2010) X. Wu et al.   SCIENCE

Crystal Structure of HIV-1 gp41 Including Both Fusion Peptide and Membrane Proximal External Regions

(2010) Victor Buzon et al.   PLoS Pathogens

Interactions of HIV-1 Antibodies 2F5 and 4E10 with a gp41 Epitope Prebound to Host and Viral Membrane Model Systems

(2009) Ana S. Veiga et al.   CHEMBIOCHEM

Novel Ring Structure in the gp41 Trimer of Human Immunodeficiency Virus Type 1 That Modulates Sensitivity and Resistance to Broadly Neutralizing Antibodies

(2009) S. M. O'Rourke et al.   JOURNAL OF VIROLOGY

Stable Docking of Neutralizing Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Monoclonal Antibodies 2F5 and 4E10 Is Dependent on the Membrane Immersion Depth of Their Epitope Regions

(2009) S. M. Dennison et al.   JOURNAL OF VIROLOGY

Relationship between Antibody 2F5 Neutralization of HIV-1 and Hydrophobicity of Its Heavy Chain Third Complementarity-Determining Region

(2009) G. Ofek et al.   JOURNAL OF VIROLOGY

Broad Neutralization of Human Immunodeficiency Virus Type 1 Mediated by Plasma Antibodies against the gp41 Membrane Proximal External Region

(2009) E. S. Gray et al.   JOURNAL OF VIROLOGY

International Network for Comparison of HIV Neutralization Assays: The NeutNet Report

(2009) Eva Maria Fenyö et al.   PLoS One

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Deletion of fusion peptide or destabilization of fusion core of HIV gp41 enhances antigenicity and immunogenicity of 4E10 epitope

(2008) Jing Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HIV-1 Broadly Neutralizing Antibody Extracts Its Epitope from a Kinked gp41 Ectodomain Region on the Viral Membrane

(2008) Zhen-Yu J. Sun et al.   IMMUNITY

Interaction of HIV-1 gp41 Core with NPF Motif in Epsin

(2008) Jing-He Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiviral compounds show enhanced activity in HIV-1 single cycle pseudovirus assays as compared to classical PBMC assays

(2008) Leo Heyndrickx et al.   JOURNAL OF VIROLOGICAL METHODS

The Membrane-Proximal External Region of the Human Immunodeficiency Virus Type 1 Envelope: Dominant Site of Antibody Neutralization and Target for Vaccine Design

(2008) M. Montero et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Avoiding the void: cell-to-cell spread of human viruses

(2008) Quentin Sattentau   NATURE REVIEWS MICROBIOLOGY

Cross-reactive HIV-1-neutralizing activity of serum IgG from a rabbit immunized with gp41 fused to IgG1 Fc: Possible role of the prolonged half-life of the immunogen

(2008) Mei-Yun Zhang et al.   VACCINE

Enhancing Exposure of HIV-1 Neutralization Epitopes through Mutations in gp41

(2007) Catherine A Blish et al.   PLOS MEDICINE