Identification of Novel Molecular Targets for Endometrial Cancer Using a Drill-Down LC-MS/MS Approach with iTRAQ

S100A6 Overexpression Is Associated with Poor Prognosis and Is Epigenetically Up-Regulated in Gastric Cancer

(2010) Xiao-Hong Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice

(2010) Hua-shan Shi et al.   CANCER SCIENCE

Development of Cathepsin Inhibitors and Structure-Based Design of Cathepsin B-Specific Inhibitor

(2010) Koji Tomoo   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Treatment options for advanced endometrial carcinoma

(2010) Don S. Dizon   GYNECOLOGIC ONCOLOGY

Proteomics-Based Approach Identified Differentially Expressed Proteins With Potential Roles in Endometrial Carcinoma

(2010) Zhengyu Li et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Efficacy of RNAi targeting of pyruvate kinase M2 combined with cisplatin in a lung cancer model

(2010) Wenhao Guo et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Endometrial carcinoma: controversies in histopathological assessment of grade and tumour cell type

(2010) B. A. Clarke et al.   JOURNAL OF CLINICAL PATHOLOGY

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

(2010) A. Le et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absolute Quantification of Potential Cancer Markers in Clinical Tissue Homogenates Using Multiple Reaction Monitoring on a Hybrid Triple Quadrupole/Linear Ion Trap Tandem Mass Spectrometer

(2009) Leroi V. DeSouza et al.   ANALYTICAL CHEMISTRY

S100A6 – New facts and features

(2009) Wiesława Leśniak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of small molecule inhibitors of pyruvate kinase M2

(2009) Matthew G. Vander Heiden et al.   BIOCHEMICAL PHARMACOLOGY

The application of mass-spectrometry-based protein biomarker discovery to theragnostics

(2009) Jonathan M. Street et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Bottleneck in the Cancer Biomarker Pipeline and Protein Quantification through Mass Spectrometry-Based Approaches: Current Strategies for Candidate Verification

(2009) S. Makawita et al.   CLINICAL CHEMISTRY

Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply

(2009) Gilles A. Spoden et al.   EXPERIMENTAL CELL RESEARCH

Proteomic Approaches to Cancer Biomarkers

(2009) Kenneth E. Hung et al.   GASTROENTEROLOGY

NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif

(2009) Yuki Kuwano et al.   NUCLEIC ACIDS RESEARCH

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Exploring the Precursor Ion Exclusion Feature of Liquid Chromatography−Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry for Improving Protein Identification in Shotgun Proteome Analysis

(2008) Nan Wang et al.   ANALYTICAL CHEMISTRY

Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence

(2008) Kotb Abdelmohsen et al.   BIOLOGICAL CHEMISTRY

Large-scale quantitative clinical proteomics by label-free liquid chromatography and mass spectrometry

(2008) Ayako Negishi et al.   CANCER SCIENCE

Proteomics-driven cancer biomarker discovery: looking to the future

(2008) Richard J Simpson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Prognostic evaluation of epidermal fatty acid-binding protein and calcyphosine, two proteins implicated in endometrial cancer using a proteomic approach

(2008) Zhengyu Li et al.   INTERNATIONAL JOURNAL OF CANCER

iTRAQ-Multidimensional Liquid Chromatography and Tandem Mass Spectrometry-Based Identification of Potential Biomarkers of Oral Epithelial Dysplasia and Novel Networks between Inflammation and Premalignancy

(2008) Ranju Ralhan et al.   JOURNAL OF PROTEOME RESEARCH

Tumor expression of S100A6 correlates with survival of patients with stage I non-small-cell lung cancer

(2008) Luigi De Petris et al.   LUNG CANCER

Pyruvate kinase M2 is a phosphotyrosine-binding protein

(2008) Heather R. Christofk et al.   NATURE

New roles for pyruvate kinase M2: working out the Warburg effect

(2008) Emily C. Ferguson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Strategies for discovering novel cancer biomarkers through utilization of emerging technologies

(2008) Vathany Kulasingam et al.   Nature clinical practice. Oncology