Identification of Human IKK-2 Inhibitors of Natural Origin (Part I): Modeling of the IKK-2 Kinase Domain, Virtual Screening and Activity Assays
出版年份 2011 全文链接
标题
Identification of Human IKK-2 Inhibitors of Natural Origin (Part I): Modeling of the IKK-2 Kinase Domain, Virtual Screening and Activity Assays
作者
关键词
-
出版物
PLoS One
Volume 6, Issue 2, Pages e16903
出版商
Public Library of Science (PLoS)
发表日期
2011-02-25
DOI
10.1371/journal.pone.0016903
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Proteus in the World of Proteins: Conformational Changes in Protein Kinases
- (2010) Matthias Rabiller et al. ARCHIV DER PHARMAZIE
- IKKβ inhibitors identification part II: Ligand and structure-based virtual screening
- (2010) Shanthi Nagarajan et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Discovery of imidazo[1,2-b]pyridazine derivatives as IKKβ inhibitors. Part 1: Hit-to-lead study and structure–activity relationship
- (2010) Hiroki Shimizu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biological evaluation of tricyclic anilinopyrimidines as IKKβ inhibitors
- (2010) Aimee L. Crombie et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Inhibition of choriodecidual cytokine production and inflammatory gene expression by selective I-κB kinase (IKK) inhibitors
- (2010) D De Silva et al. BRITISH JOURNAL OF PHARMACOLOGY
- IKK-β inhibitors: An analysis of drug–receptor interaction by using Molecular Docking and Pharmacophore 3D-QSAR approaches
- (2010) Antonino Lauria et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Cordyceps fungi: natural products, pharmacological functions and developmental products
- (2010) Xuanwei Zhou et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Synthesis of Natural Product Inspired Compound Collections
- (2009) Kamal Kumar et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The Current Status of Drug Discovery Against the Human Kinome
- (2009) Richard M. Eglen et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- IKKβ inhibitors identification part I: Homology model assisted structure based virtual screening
- (2009) Shanthi Nagarajan et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Structural insights into IKKβ inhibition by natural products staurosporine and quercetin
- (2009) Carolina M. Avila et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- 4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors
- (2009) John Liddle et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Inhibition of IKK-β: A new development in the mechanism of the anti-obesity effects of PTP1B inhibitors SA18 and SA32
- (2009) Bharat Raj Bhattarai et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery of 6-Aryl-7-alkoxyisoquinoline Inhibitors of IκB Kinase-β (IKK-β)
- (2009) John A. Christopher et al. JOURNAL OF MEDICINAL CHEMISTRY
- Novel Tight-Binding Inhibitory Factor- B Kinase (IKK-2) Inhibitors Demonstrate Target-Specific Anti-Inflammatory Activities in Cellular Assays and following Oral and Local Delivery in an in Vivo Model of Airway Inflammation
- (2009) C. D. Sommers et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A Novel, Highly Selective, Tight Binding I B Kinase-2 (IKK-2) Inhibitor: A Tool to Correlate IKK-2 Activity to the Fate and Functions of the Components of the Nuclear Factor- B Pathway in Arthritis-Relevant Cells and Animal Models
- (2009) G. Mbalaviele et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Identification of a chemical probe for NAADP by virtual screening
- (2009) Edmund Naylor et al. Nature Chemical Biology
- Nature: a vital source of leads for anticancer drug development
- (2009) G. M. Cragg et al. PHYTOCHEMISTRY REVIEWS
- 3D-QSAR Study of Pyridine Derivates as IKK-2 Inhibitors
- (2009) Esther Sala et al. Quantitative structure-activity relationships & combinatorial science
- Synthesis and structure–activity relationship of aminopyrimidine IKK2 inhibitors
- (2008) Alistair H. Bingham et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- IκB kinase β (IKKβ/IKK2/IKBKB)—A key molecule in signaling to the transcription factor NF-κB
- (2008) Johannes A. Schmid et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Natural products in drug discovery
- (2008) A HARVEY DRUG DISCOVERY TODAY
- Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites
- (2008) Ashley C W Pike et al. EMBO JOURNAL
- Knowledge Based Prediction of Ligand Binding Modes and Rational Inhibitor Design for Kinase Drug Discovery
- (2008) Arup K. Ghose et al. JOURNAL OF MEDICINAL CHEMISTRY
- Kinase inhibitors for the treatment of inflammatory and autoimmune disorders
- (2008) Shripad S. Bhagwat Purinergic Signalling
- Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site
- (2008) Mia Rushe et al. STRUCTURE
- Panning for chemical gold: marine bacteria as a source of new therapeutics
- (2008) Philip G. Williams TRENDS IN BIOTECHNOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search