Article
Chemistry, Multidisciplinary
Ying Xu, Yufan Wang, Fu-Sen Liang
Summary: Conditional m(6)A editing platform based on a ligand stabilized dCas13 editor was developed, allowing inducible expression of the editing system by controlling the presence of a specific molecule. This platform reduces interference from the bulky CRISPR protein and constitutively expressed editing enzymes in target RNAs and cells.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Analytical
Fabrizio Sgobba, Andrea Andrisani, Stefano Dello Russo, Mario Siciliani de Cumis, Luigi Santamaria Amato
Summary: In this paper, a highly sensitive single photon birefringence-induced delay sensor operating in the telecom range (1550 nm) is developed. By using a temporal quantum eraser based on common path Hongr-Ou-Mandel Interferometry, a sensitivity of 4 is achieved for an integration time of 2 center dot 104 s.
Article
Neurosciences
Todd Charlton Sacktor
Summary: Karim Nader's research explores memory reconsolidation and memory maintenance by PKM zeta. He found that inhibiting PKM zeta or blocking reconsolidation can erase long-term memory. The study also revealed a connection between PKM zeta's regulation of AMPAR trafficking and memory maintenance. PKM zeta inhibition erases all memories stored by the kinase, while reconsolidation blockade disrupts specific recalled memories by preventing the resynthesis of PKM zeta.
BRAIN RESEARCH BULLETIN
(2023)
Article
Computer Science, Software Engineering
Xuewei Bian, Chaoqun Wang, Weize Quan, Juntao Ye, Xiaopeng Zhang, Dong-Ming Yan
Summary: This paper proposes a novel end-to-end framework based on accurate text stroke detection for the scene text removal task. Experimental results demonstrate that the proposed method outperforms the state-of-the-art for locating and erasing scene text. Additionally, a new large-scale real-world dataset has been constructed to facilitate research.
COMPUTATIONAL VISUAL MEDIA
(2022)
Article
Chemistry, Multidisciplinary
Kexin Jiao, Nathalie Becerra-Mora, Brice Russell, Aldo Migone, Max E. Gemeinhardt, Boyd M. Goodson, Punit Kohli
Summary: Simultaneous writing and erasing of multiple molecules at the microscale using Polymeric Lithography Editor (PLE) probes has been demonstrated. The writing and erasing speed can be easily adjusted by tuning the probe speed, allowing for high-quality editing of microscale patterns at high speeds.
Review
Neurosciences
Jianfeng Liu
Summary: The stress system in the brain plays a crucial role in protecting humans and animals from harmful stimuli. Excessive stress can lead to maladaptive changes in the stress system and result in depression. Recent evidence suggests that PKM zeta is involved in stress response and depressive-like behavior, and it could be a molecular target for developing novel antidepressants.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Clinical Neurology
T. Jordan Walter, Jared W. Young, Morgane Milienne-Petiot, D. S. Deben, Robert K. Heaton, Scott Letendre, David J. Grelotti, William Perry, Igor Grant, Arpi Minassian
Summary: HIV infection and methamphetamine use can negatively impact brain functions. Research on mice and humans indicates that the combination of HIV and methamphetamine may additively impair sensorimotor gating, potentially affecting cognitive function.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2021)
Article
Biology
Masaaki Hayashi, Kohei Okuyama, Nobuaki Mizuguchi, Ryotaro Hirose, Taisuke Okamoto, Michiyuki Kawakami, Junichi Ushiba
Summary: This study used EEG neurofeedback technique to enable participants to modulate their bilateral sensorimotor activities. The results showed that participants learned to regulate the excitability of the ipsilateral hand, thereby modulating the inhibition between the two brain hemispheres. Further analysis revealed that the modulation capability of inhibition magnitude was related to interhemispheric connectivity in EEG and TMS, as well as bilateral cortical oscillatory activities.
Review
Biology
Ensor Rafael Palacios, Conor Houghton, Paul Chadderton
Summary: The review discusses the possible contribution of inhibition to the encoding of precision of neural representations in the granular layer of the cerebellar cortex, emphasizing the critical role of Golgi cells in shaping information transmission downstream to Purkinje cells.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2021)
Article
Mathematics, Applied
Alessandro Della Corte, Stefano Isola, Riccardo Piergallini
Summary: This work begins the study of a new class of dynamical systems determined by interval maps generated by the symbolic action of erasing substitution rules. It discusses in detail the geometric, analytical, dynamical, and arithmetic properties of a specific example, which is argued to be the simplest and yet produces interesting properties and new challenging problems.
Article
Neurosciences
Bia Lima Ramalho, Julien Moly, Estelle Raffin, Romain Bouet, Sylvain Harquel, Alessandro Farne, Karen T. Reilly
Summary: This study investigated sensorimotor interactions between the face and hand using an afferent inhibition transcranial magnetic stimulation protocol. The results showed that facial stimulation can inhibit hand muscle motor responses, providing the first evidence for face-to-hand afferent inhibition.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Optics
Jose Alfredo de Leon, Alejandro Fonseca, Francois Leyvraz, David Davalos, Carlos Pineda
Summary: This article proposes a method for translating quantum systems in a multiparticle environment, by preserving or erasing the components of a multiqubit system using the basis of Pauli strings. The preserved components are interpreted as a finite vector subspace, and the obtained family of channels is shown to form a semigroup with its generators determined. The physical implementations of the channels are also discussed and connected with Markovian processes.
Article
Biology
Ann-Kristin Meyer, Roland G. Benoit
Summary: This study examines the impact of suppression on memories and finds that suppression leads to a reduction in memory vividness and neural reactivation.
Editorial Material
Immunology
Fei Yi, Christopher A. Klebanoff
Summary: CRISPR-Cas9 is a powerful tool for genetic screens, but vector immunogenicity may introduce artifacts. A new strategy to erase vector-associated neoantigens has been reported in a recent study, allowing a more physiologic assessment of tumor-immune cell interactions in immunocompetent hosts.
Article
Psychology
Xuehui Lei, Weimin Mou
Summary: This study investigated the development of global spatial representations of a multiroom environment through physical walking and found a global sensorimotor alignment effect in JRD after across-boundary walking.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-LEARNING MEMORY AND COGNITION
(2022)