Responsiveness to PI3K and MEK Inhibitors in Breast Cancer. Use of a 3D Culture System to Study Pathways Related to Hormone Independence in Mice

Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins

(2009) Remedios Castelló-Cros et al.   BMC CANCER

Basal Subtype and MAPK/ERK Kinase (MEK)-Phosphoinositide 3-Kinase Feedback Signaling Determine Susceptibility of Breast Cancer Cells to MEK Inhibition

(2009) O. K. Mirzoeva et al.   CANCER RESEARCH

The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer

(2009) Claudia Lanari et al.   ENDOCRINE-RELATED CANCER

Estradiol-Induced Regression in T47D:A18/PKC  Tumors Requires the Estrogen Receptor and Interaction with the Extracellular Matrix

(2009) Y. Zhang et al.   MOLECULAR CANCER RESEARCH

Factors underlying sensitivity of cancers to small-molecule kinase inhibitors

(2009) Pasi A. Jänne et al.   NATURE REVIEWS DRUG DISCOVERY

Reversal of antiprogestin resistance and progesterone receptor isoform ratio in acquired resistant mammary carcinomas

(2008) Victoria Wargon et al.   BREAST CANCER RESEARCH AND TREATMENT

A spontaneous estrogen dependent, tamoxifen sensitive mouse mammary tumor: a new model system to study hormone-responsiveness in immune competent mice

(2008) Marina Simian et al.   BREAST CANCER RESEARCH AND TREATMENT

Establishment of an in vitro estrogen-dependent mouse mammary tumor model: a new tool to understand estrogen responsiveness and development of tamoxifen resistance in the context of stromal–epithelial interactions

(2008) Osvaldo Pontiggia et al.   BREAST CANCER RESEARCH AND TREATMENT

Combination of Anastrozole with Fulvestrant in the Intratumoral Aromatase Xenograft Model

(2008) L. F. Macedo et al.   CANCER RESEARCH

Crosstalk between the Estrogen Receptor and the HER Tyrosine Kinase Receptor Family: Molecular Mechanism and Clinical Implications for Endocrine Therapy Resistance

(2008) Grazia Arpino et al.   ENDOCRINE REVIEWS

Carcinoma-associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF-2/FGFR-2 axis

(2008) Sebastián Giulianelli et al.   INTERNATIONAL JOURNAL OF CANCER

The Relevance of Mouse Models to Understanding the Development and Progression of Human Breast Cancer

(2008) D. Craig Allred et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Unraveling the microenvironmental influences on the normal mammary gland and breast cancer

(2008) Britta Weigelt et al.   SEMINARS IN CANCER BIOLOGY

A Novel 3D In Vitro Culture Model to Study Stromal–Epithelial Interactions in the Mammary Gland

(2008) Silva Krause et al.   TISSUE ENGINEERING PART C-METHODS

Breast cancer by proxy: can the microenvironment be both the cause and consequence?

(2008) Lone Rønnov-Jessen et al.   TRENDS IN MOLECULAR MEDICINE