Carboxy Terminal Tail of Polycystin-1 Regulates Localization of TSC2 to Repress mTOR

Autosomal dominant polycystic kidney disease: Emerging concepts of pathogenesis and new treatments

(2009) W. E. BRAUN   CLEVELAND CLINIC JOURNAL OF MEDICINE

Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis

(2009) Cleo S. Bonnet et al.   HUMAN MOLECULAR GENETICS

Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment

(2009) K. Inoki et al.   HUMAN MOLECULAR GENETICS

Polycystin-1 Regulates Extracellular Signal-Regulated Kinase-Dependent Phosphorylation of Tuberin To Control Cell Size through mTOR and Its Downstream Effectors S6K and 4EBP1

(2009) G. Distefano et al.   MOLECULAR AND CELLULAR BIOLOGY

Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis

(2009) Kristen Pollizzi et al.   Molecular Cancer

Activation of the AKT/mTOR pathway in autosomal recessive polycystic kidney disease (ARPKD)

(2009) D.-C. Fischer et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL

The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway

(2008) Tiffiney R. Hartman et al.   HUMAN MOLECULAR GENETICS

Polycystin-1 C-terminal tail associates with β-catenin and inhibits canonical Wnt signaling

(2008) Mark Lal et al.   HUMAN MOLECULAR GENETICS

Autosomal Dominant Polycystic Kidney Disease: Recent Advances in Pathogenesis and Treatment

(2007) Ming-Yang Chang et al.   NEPHRON PHYSIOLOGY