Review
Biochemistry & Molecular Biology
Laura Barsanti, Lorenzo Birindelli, Francesca Sbrana, Giovanni Lombardi, Paolo Gualtieri
Summary: Microscopy, when combined with other instruments, can perform quantitative measurements and improve non-destructive investigations. This review focuses on three advanced microscopy techniques, including microspectrophotometry, super-resolution localization microscopy, and holotomographic microscopy, which provide insights into the role of intracellular molecular organizations and their biophysical properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Automation & Control Systems
Mishek Jair Musa, Karun Sharma, Kevin Cleary, Yue Chen
Summary: This article presents a patient-mounted, respiratory compensated robotic needle insertion platform for percutaneous needle interventions. The platform shows good mechanical characteristics and positioning accuracy, demonstrating promising results in both phantom and ex vivo porcine liver experiments.
IEEE-ASME TRANSACTIONS ON MECHATRONICS
(2022)
Article
Chemistry, Multidisciplinary
Mingjing Cao, Kai Zhang, Shuhan Zhang, Yaling Wang, Chunying Chen
Summary: The interaction between nanomaterials and biology plays a crucial role in the biological behavior and fate of nanoparticles. However, it has been challenging to analyze the transport and transformation of nanomedicines in real-time and label-free. The advancements in advanced light source (ALS) technologies offer new opportunities for studying the behavior and fate of nanomedicines in vivo.
ACS CENTRAL SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Mingjing Cao, Kai Zhang, Shuhan Zhang, Yaling Wang, Chunying Chen
Summary: Understanding the biological behavior and fate of nanomedicines is crucial for their design and clinical translation, and advanced light source (ALS) analytical technologies, with higher spatial and temporal resolution, multimodal data fusion, and intelligent prediction abilities, have the potential to unlock this knowledge. However, current approaches face challenges and limitations.
ACS CENTRAL SCIENCE
(2022)
Review
Chemistry, Physical
Min-cheol Kim, So-Yeon Ham, Diyi Cheng, Thomas A. Wynn, Hyun Suk Jung, Ying Shirley Meng
Summary: In the past decade, organic-inorganic hybrid perovskite solar cells have made unprecedented progress but face challenges in long-term stability and areal scalability. Advanced diagnostic tools such as cryogenic temperature assisted measurements, in situ measurements, and multidimensional mapping techniques can help overcome characterization challenges caused by factors like degradation from the measurement source.
ADVANCED ENERGY MATERIALS
(2021)
Article
Polymer Science
Yujun Wan, Sheena M. H. Chua, Yin Yao, Lewis Adler, Marta Navarro, Eugeni Roura, Richard D. Tilley, Changfeng Li, Lars Nilsson, Robert G. Gilbert, Mitchell A. Sullivan
Summary: This study compared the effectiveness of different techniques in analyzing glycogen size distributions. Combining size-separation and microscopy techniques can provide a comprehensive view of glycogen size distribution and morphology. However, microscopy techniques provide richer morphological information, while size-separation techniques have better resolution.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Polymer Science
Xiaozhi Ouyang, Cheng Huang, Sha Cheng, Pengchao Zhang, Wen Chen
Summary: In this study, a microfluidic-based strategy for the continuous fabrication of ultrathin hydrogel films was proposed. This strategy allows for precise control over the thickness of the hydrogel films and can be scaled up. The method shows advantages in producing high uniformity and structural integrity of the hydrogel films without the need for supporting substrates and sophisticated equipment. Therefore, this strategy provides a facile route to produce advanced thin polymer films and promotes their applications in biosensors and wearable electronics.
Article
Engineering, Multidisciplinary
Omid Babaie Rizvandi, Xing-Yuan Miao, Henrik Lund Frandsen
Summary: The use of Darcy's Law (DL) to approximate flows in channels with circular and arbitrary cross-sections significantly reduces computational resources and improves model stability and convergence. The DL approximations reduce runtime by approximately 40 times compared to RANS, while accurately predicting velocity and pressure distributions in laminar and turbulent flows.
ALEXANDRIA ENGINEERING JOURNAL
(2021)
Article
Engineering, Environmental
Ana Elena Pradas del Real, Denise M. Mitrano, Hiram Castillo-Michel, Mohammad Wazne, Juan Reyes-Herrera, Emely Bortel, Bernhard Hesse, Julie Villanova, Geraldine Sarret
Summary: Despite the increasing attention given to nanoplastics in terrestrial environments, there is limited data on their effects on plants and uptake. This study exposed wheat plants grown in hydroponics to Pd-doped nanoplastics, allowing for quantification of nanoplastics uptake and translocation. Synchrotron micro X-ray fluorescence was used to visualize nanoplastics in roots, which were found to accumulate on the root epidermis, especially at the root tip and in mature zones. The study also demonstrated a relationship between plant roots, rhizodeposits, and nanoplastics behavior.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Review
Pharmacology & Pharmacy
Chengying Zhang, Zhiqi Tian, Rui Chen, Fiona Rowan, Kangqiang Qiu, Yujie Sun, Jun-Lin Guan, Jiajie Diao
Summary: Optical microscopes have advanced modern biomedicine and super-resolution microscopy (SRM) has become popular in the life sciences, especially in living cell imaging. SRM has been used to study drug delivery and kinetics at the subcellular level, providing insights into drug mechanisms and efficacy assessment. This paper reviews recent advances in SRM and its applications in assessing subcellular drug dynamics.
ADVANCED DRUG DELIVERY REVIEWS
(2023)
Article
Food Science & Technology
Alper Soyler, Sevil Cikrikci, Cagri Cavdaroglu, Dylan Bouillaud, Jonathan Farjon, Patrick Giraudeau, Mecit H. Oztop
Summary: This study investigated the application of benchtop NMR spectroscopy in analyzing milk in an industrial context, focusing on production quality and product differentiation. Through quantitative online NMR spectroscopy, lactose hydrolysis in milk was tracked and different milk samples were successfully differentiated based on their properties.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Cheng Zhou, Nanqing Shi, Xue Jiang, Mingrui Chen, Jinlei Jiang, Youbin Zheng, Weiwei Wu, Daxiang Cui, Hossam Haick, Ning Tang
Summary: Wearable gas sensors are gaining significant attention due to their portable and real-time monitoring capabilities. However, limited fabrication techniques and challenges with flexible substrates have restricted their development. Recent advances in fabrication techniques including coating, printing, spinning, and transferring methods have been discussed in detail to address these issues.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Multidisciplinary
Mahtab Masouminia, Kari Dalnoki-Veress, Charles-Francois de Lannoy, Benzhong Zhao
Summary: Wettability is crucial in controlling multiphase flow in porous media for various industrial applications. NOA81, a thiolene-based polymer, has been considered an ideal material for fabricating microfluidic devices due to its tunable wettability. However, the underlying mechanisms of wettability alteration by UV-ozone exposure are not fully understood. In this study, we used contact angle measurements, XPS, and AFM to investigate the impact of UV-ozone on the chemical and physical properties of NOA81 surfaces. Our findings reveal that UV-ozone exposure increases the surface energy and hydrophilicity of NOA81 by enhancing oxygen-containing polar functional groups.
Review
Biochemistry & Molecular Biology
Rohin Shyam, L. Vinod Kumar Reddy, Arunkumar Palaniappan
Summary: The culturing of cells in the laboratory is crucial for scientific research. Cell-based assays provide simple and cost-effective methods in drug discovery and disease modeling. The techniques involved in culturing cells are critical for studying cellular response to various factors.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Automation & Control Systems
Daniel J. Thomas
Summary: The aim of this study was to evaluate the redesign and additive manufacturing of a rocket engine nozzle using Inconel 625 material. The redesigned engine took into consideration material shrinkage during the metal transfer process. The additive manufacturing process was carried out using the appropriate toolpaths to form a solid structure. The micrographs of the additively manufactured structure showed layer resolution and fine detail, as well as the presence of metallic particles within the polymer matrix. The final rocket engine nozzle produced was found to have the necessary mechanical and metallurgical properties required for practical use in future space vehicle operations. This was demonstrated by tensile tests carried out at various temperatures and 3D white light interferometry scans of the surface properties. The results of the study suggest that additive manufacturing and Inconel 625 material can be used to produce high-performance rocket engine nozzles that meet the requirements of the aerospace industry. This study provides valuable insights into the potential applications of additive manufacturing in the aerospace industry and may lead to the development of new, high-performance rocket engine nozzles.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2023)