Comparative Sequence and Structural Analyses of G-Protein-Coupled Receptor Crystal Structures and Implications for Molecular Models

Revisiting Automated G-Protein Coupled Receptor Modeling: The Benefit of Additional Template Structures for a Neurokinin-1 Receptor Model

(2009) Benny Kneissl et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural determinants for selective recognition of peptide ligands for endothelin receptor subtypes ETAand ETB

(2009) Jens Lättig et al.   JOURNAL OF PEPTIDE SCIENCE

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation

(2009) Shivani Ahuja et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-Level Production, Solubilization and Purification of Synthetic Human GPCR Chemokine Receptors CCR5, CCR3, CXCR4 and CX3CR1

(2009) Hui Ren et al.   PLoS One

Identification of two distinct inactive conformations of the  2-adrenergic receptor reconciles structural and biochemical observations

(2009) R. O. Dror et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of New GPCR Biology: One Receptor Structure at a Time

(2009) Michael A. Hanson et al.   STRUCTURE

Molecular and structural effects of inverse agonistic mutations on signaling of the thyrotropin receptor – a basally active GPCR

(2008) G. Kleinau et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region

(2008) Tatsuro Shimamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On the Applicability of GPCR Homology Models to Computer-Aided Drug Discovery: A Comparison between In Silico and Crystal Structures of the β2-Adrenergic Receptor

(2008) Stefano Costanzi   JOURNAL OF MEDICINAL CHEMISTRY

Agonist-Induced Conformational Changes in Bovine Rhodopsin: Insight into Activation of G-Protein-Coupled Receptors

(2008) Supriyo Bhattacharya et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

Crystal structure of opsin in its G-protein-interacting conformation

(2008) Patrick Scheerer et al.   NATURE

Crystal structure of squid rhodopsin

(2008) Midori Murakami et al.   NATURE

Crystal structure of the ligand-free G-protein-coupled receptor opsin

(2008) Jung Hee Park et al.   NATURE

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

(2008) Deborah J. Smyth et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Heterozygous Mutation in the Third Transmembrane Domain Causes a Dominant-Negative Effect on Signalling Capability of the MC4R

(2008) Patrick Tarnow et al.   Obesity Facts

Improved yield of a ligand-binding GPCR expressed in E. coli for structural studies

(2008) Helen Attrill et al.   PROTEIN EXPRESSION AND PURIFICATION

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE

Understanding the structural and functional differences between mouse thyrotropin-releasing hormone receptors 1 and 2

(2007) Francesca Deflorian et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS