Article
Biochemistry & Molecular Biology
Angelo Antonio Barbosa de Moraes, Celeste de Jesus Pereira Franco, Oberdan Oliveira Ferreira, Everton Luiz Pompeu Varela, Lidiane Diniz do Nascimento, Marcia Moraes Cascaes, Dehon Ricardo Pereira da Silva, Sandro Percario, Mozaniel Santana de Oliveira, Eloisa Helena de Aguiar Andrade
Summary: This study reports the productivity, chemical composition, and antioxidant profile of the essential oil of Myrcia paivae, a species from the Myrtaceae family in the Amazon. The essential oil showed a production rate of 1.69% and predominantly consisted of hydrocarbon monoterpenes. It exhibited good antioxidant capacity, attributed to its high monoterpene content.
Article
Immunology
Andreza Larissa do Nascimento, Joyce Bezerra Guedes, Wendeo Kennedy Costa, Bruno Oliveira de Veras, Julio Cesar Ribeiro de Oliveira Farias de Aguiar, Daniela Maria do Amaral Ferraz Navarro, Maria Tereza dos Santos Correia, Thiago Henrique Napoleao, Alisson Macario de Oliveira, Marcia Vanusa da Silva
Summary: This study is the first to identify the components of Eugenia pohliana essential oil and evaluate its antinociceptive and anti-inflammatory activities. The major components of the oil are (E)-beta-caryophyllene, delta-cadinene, and alpha-cadinol. The results showed that the essential oil has significant antinociceptive and anti-inflammatory effects, acting through the activation of opioid receptors.
INFLAMMOPHARMACOLOGY
(2022)
Article
Plant Sciences
Leidiana Lima dos Santos, Felix Forest, Duane Fernandes Lima, Margareth F. Sales, Thais Nogales Vasconcelos, Vanessa G. Staggemeier, Eve Lucas
Summary: This study examines phylogenetic relationships and biogeographic patterns in Myrcia sect. Myrcia based on molecular data for the first time. The results show that the section is monophyletic as morphologically circumscribed, but the widespread M. splendens is polyphyletic. Lineages from Central America and the Amazon are sister to multiple dispersals to disparate biomes and colonization of the Cerrado. The mean estimated age for Myrcia sect. Myrcia is 22.4 million years ago, with the four clades of focus originating in the Miocene.
INTERNATIONAL JOURNAL OF PLANT SCIENCES
(2021)
Article
Plant Sciences
Scheila Iria Kraus, Jeane Bachi Ferreira, Jhonatan Augusto Ribeiro, Kelly Cattelan Bonorino, Vinicius Alexandre Wippel, Michele Debiasi Alberton, Andreia Caroline Fernandes Salgueiro, Carlos Henrique Lemos Soares, Morgana Duarte da Silva
Summary: This study evaluated the toxicological effects of Eugenia brasiliensis and its antinociceptive and anti-inflammatory activity. The results showed that the extract did not have significant toxic effects and exhibited important antinociceptive, anti-inflammatory, and antioxidant potential.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Plant Sciences
Leidiana Lima Dos Santos, Thais Nogales DA Costa Vasconcelos, Margareth Ferreira DE Sales, Eve Lucas
Summary: Three new species of Myrcia are described, illustrated and compared based on their different characteristics such as leaf apex shape, fruit surface features, and flower bud size.
Article
Chemistry, Applied
Pamela Pacassa Borges, Larissa Benvenutti, Aline Lana Schneider, Marcelo Rodrigo Franke Echterhoff, Bruna Goncalves Lopes, Diogo Alexandre Siebert, Gustavo Amadeu Micke, Luciano Vitali, Michele Debiasi Alberton, Nara Lins Meira Quintao, Jose Roberto Santin, Isabel Daufenback Machado
Summary: We investigated the anti-inflammatory activity of Myrcia pubipetala's crude hydroalcoholic extract (CHE-MP) and found that it significantly reduced the levels of nitric oxide, interleukin-1 beta, interleukin-6, and tumor necrosis factor in inflammatory cells. It also decreased neutrophil migration, indicating its potential as an anti-inflammatory agent.
NATURAL PRODUCT RESEARCH
(2023)
Article
Plant Sciences
Natalia de Matos Balsalobre, Elisangela Dos Santos, Sidney Mariano Dos Santos, Arielle Cristina Arena, Elisabete Castelon Konkiewitz, Edward Benjamin Ziff, Anelise Samara Nazari Formagio, Candida Aparecida Leite Kassuya
Summary: The aim of this study was to investigate the analgesic and anti-arthritic properties of EOAE and viridiflorol using in vivo models.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Angelo Antonio Barbosa de Moraes, Oberdan Oliveira Ferreira, Leonardo Souza da Costa, Lorena Queiroz Almeida, Everton Luiz Pompeu Varela, Marcia Moraes Cascaes, Celeste de Jesus Pereira Franco, Sandro Percario, Lidiane Diniz do Nascimento, Mozaniel Santana de Oliveira, Eloisa Helena de Aguiar Andrade
Summary: This study analyzed the essential oils of Myrciaria floribunda and Myrcia sylvatica obtained by hydrodistillation and assessed their toxicity and antioxidant capacity. The results showed that Myrciaria floribunda essential oil contained high levels of hydrocarbon and oxygenated monoterpenes, while Myrcia sylvatica essential oil contained hydrocarbon and oxygenated sesquiterpenes. Myrciaria floribunda essential oil exhibited moderate toxicity against Artemia salina, while Myrcia sylvatica essential oil was highly toxic. Additionally, both essential oils showed significant inhibitory effects against the DPPH radical.
Article
Plant Sciences
Valquiria Bruna Guimaraes Silva, Beatriz Meyruze Barros da Fonseca, Julio Cesar Ribeiro de Oliveira Farias de Aguiar, Daniela Maria do Amaral Ferraz Navarro, Alisson Macario de Oliveira, Thiago Henrique Napolea, Maria Tereza dos Santos Correia, Vera Lucia de Menezes Lima, Wendeo Kennedy Costa, Marcia Vanusa da Silva
Summary: The aim of this study was to evaluate the antinociceptive and anti-inflammatory potential of Psidium cattleyanum leaves essential oil. Gas chromatography-mass spectrometry (GC/MS) was used to analyze the oil. The results showed that the essential oil has significant antinociceptive and anti-inflammatory effects, and has potential for application in the pharmaceutical and food industry.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Jose Nabor Haro-Gonzalez, Gustavo Adolfo Castillo-Herrera, Moises Martinez-Velazquez, Hugo Espinosa-Andrews
Summary: Clove is an aromatic plant rich in volatile compounds and antioxidants. Clove essential oil, with its major compound eugenol, has diverse biological activities beneficial for human health. Different extraction methods can affect the concentration of volatile compounds in clove essential oil, influencing its chemical composition and applications.
Article
Biochemistry & Molecular Biology
Celeste de Jesus Pereira Franco, Oberdan Oliveira Ferreira, Angelo Antonio Barbosa de Moraes, Everton Luiz Pompeu Varela, Lidiane Diniz do Nascimento, Sandro Percario, Mozaniel Santana de Oliveira, Eloisa Helena de Aguiar Andrade
Summary: Essential oils were extracted from Eugenia patrisii, E. punicifolia, and Myrcia tomentosa using hydrodistillation, with major volatile constituents identified by GC/MS. The antioxidant capacity of the oils was determined through DPPH and TEAC assays, showing variation between different specimens and collection periods. The EOs, especially from E. punicifolia, exhibited higher antioxidant activity in DPPH assays compared to TEAC.
Article
Chemistry, Applied
Marcia M. Cascaes, Giselle M. S. P. Guilhon, Maria das Gracas Zoghbi, Eloisa Helena A. Andrade, Lourivaldo S. Santos, Joyce Kelly R. da Silva, Ana Paula Trovatti Uetanabaro, Isabella S. Araujo
Summary: This study presents the first chemical investigation of the methanol extract of Myrcia rufipila leaves collected in Maracana Municipality, Para, Brazil, revealing the presence of flavonoids, triterpenoids, and other compounds with antioxidant capacity and antimicrobial effects. The findings suggest that Myrcia rufipila is a potential source of bioactive compounds with potential health benefits.
NATURAL PRODUCT RESEARCH
(2021)
Article
Plant Sciences
Laura C. De lannoy, Ayrton I. De Oliveira, Renato Goldenberg, Duane F. Lima
Summary: Myrtaceae is one of the largest families in terms of species within the order Myrtales, and is particularly diverse in Brazil. Myrcia, the fourth largest genus in Myrtaceae, has 770 species distributed across Central and South America. This study focuses on the taxonomic treatment of Myrcia species in Parana state, Brazil, identifying 53 species in total, none of which are endemic to the region. The state serves as both the southern and northern distribution limits for certain species.
Article
Integrative & Complementary Medicine
Monalisa Martins Montalvao, Franciel Batista Felix, Edmilson William Propheta dos Santos, Jileno Ferreira Santos, Waldecy de Lucca Junior, Atenilton Santos Farias, Adauto de Souza Ribeiro, Carlos Cavaleiro, Samisia Maria Fernandes Machado, Ricardo Scher, Cristiane Bani Correa
Summary: In this study, the essential oil from M. splendens leaves was analyzed and its cytotoxic effect on A549 lung cancer cells was evaluated. The results showed that the essential oil exhibited cytotoxic activity against the lung cancer cells and inhibited their colony formation and migratory capacity. This study provides valuable compounds for further investigation of lung cancer treatment.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2023)
Article
Plant Sciences
Rayza Helen Graciano dos Santos, Maira Honorato de Moura Silva, Julio Cesar Ribeiro de Oliveira Farias de Aguiar, Daniela Maria do Amaral Ferraz Navarro, Antonio Fernando Morais de Oliveira, Maria Tereza dos Santos Correia
Summary: The chemical composition of Myrcia loranthifolia leaf essential oil from Atlantic Forest and Dry Forest of Brazil was evaluated. Qualitative and quantitative differences were found depending on the geographical origin of the plant, possibly due to abiotic factors or genetic characteristics.
BRAZILIAN JOURNAL OF BOTANY
(2023)
Article
Chemistry, Applied
Aurelio de Oliveira Monteiro, Jarbas Lima de Carvalho, Horlando Carlota da Silva, Gerlan Oliveira do Nascimento, Ana Maria Amaral Silva, Maria Teresa Salles Trevisan, Gilvandete Maria Pinheiro Santiago
Summary: Phytochemical investigation of the stems of B. pulchella resulted in the isolation of various known compounds, some of which exhibited antioxidant and enzyme inhibitory activities. The study also revealed the first-time isolation of compounds 11 and 12 from this genus.
NATURAL PRODUCT RESEARCH
(2022)
Article
Chemistry, Applied
Victor de Carvalho Martins, Manuela Cristina Pessanha de Araujo Santiago, Sidney Pacheco, Renata Galhardo Borguini, Marcelo da Costa Souza, Mario Geraldo de Carvalho, Ronoel Luiz de Oliveira Godoy
Summary: This study for the first time revealed the chemical composition of Myrcia eriopus fruit, showing high levels of anthocyanins and antioxidant potential. It demonstrates the fruit's potential as a new source of bioactive anthocyanins.
NATURAL PRODUCT RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Matheus Andrade Rocha Costa, Simone Andrade Gualberto, Polyany Cabral Oliveira, Iasnaia Maria de Carvalho Tavares, Nivio Batista Santana, Danilo Junqueira Leao, Debora Cardoso da Silva, Dhiessica Dos Santos Ribeiro, Neura Mendes da Silva, Pedro Henrique Santos, Mario Geraldo de Carvalho, Marcelo Franco
Summary: This study evaluated enzymatic pretreatment and hydrodistillation to increase the extraction efficiency of essential oil from Croton argyrophyllus leaves. The results showed that enzymatic pretreatment increased essential oil yield by 9.35% for fresh leaves and 6.77% for dry leaves under optimal experimental conditions. This approach holds promise for obtaining essential oil for therapeutic purposes without altering its composition.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
(2022)
Article
Entomology
Gracieli Gomes Nonato Bressanin, Caio Marcio de Oliveira Monteiro, Paula Marchesini, Tatiane Pinheiro Lopes Novato, Francisco Eduardo Aragao Catunda Junior, Sabrina Rita Da Fonseca Rezende, Emerson Guedes Pontes, Mario Geraldo de Carvalho, Andreia Lima Tome Melo, Wendell Marcelo de Souza Perinotto
Summary: The study found that the essential oil from Curcuma zedoaria exhibited good acaricidal activity against Rhipicephalus microplus, while the oil from Alpinia zerumbet had a lesser effect. The major components in Curcuma zedoaria oil, such as 1,8-cineole, curzerenone and camphor, may contribute to its efficacy.
INTERNATIONAL JOURNAL OF ACAROLOGY
(2022)
Article
Entomology
Juliana Aparecida Diniz, Paula Marchesini, Viviane Zeringota, Renata da Silva Matos, Tatiane Pinheiro Lopes Novato, Diego Melo, Leticia Vale, Welber Daniel Zanetti Lopes, Geovany Amorim Gomes, Caio Monteiro
Summary: The study revealed variations in the chemical composition of essential oils from Siparuna guianensis in different regions, with chemotypes rich in alpha-bisabolol showing greater acaricidal activity against Rhipicephalus microplus.
INTERNATIONAL JOURNAL OF ACAROLOGY
(2022)
Article
Endocrinology & Metabolism
Tassiana Cristina Talpo, Bruno Pereira Motta, Juliana Oriel de Oliveira, Ingrid Delbone Figueiredo, Camila Graca Pinheiro, Carlos Henrique Correa dos Santos, Mario Geraldo de Carvalho, Iguatemy Lourenco Brunetti, Amanda Martins Baviera
Summary: The study showed that Siolmatra brasiliensis extract has antiobesogenic effects, improves insulin sensitivity and glucose tolerance, reduces total cholesterol levels, decreases levels of glycoxidative stress biomarkers, and improves endogenous antioxidant defenses.
OBESITY RESEARCH & CLINICAL PRACTICE
(2022)
Article
Infectious Diseases
Vinicius de Queiroz Albuquerque, Maria Janeila Carvalho Soares, Maria Nagila Carneiro Matos, Rafaela Mesquita Bastos Cavalcante, Jesus Alberto Perez Guerrero, Tigressa Helena Soares Rodrigues, Geovany Amorim Gomes, Rodrigo Fonseca de Medeiros Guedes, Debora de Souza Collares Maia Castelo-Branco, Isaac Neto Goes da Silva, Victor Alves Carneiro
Summary: This study evaluated the phytochemical composition of Cinnamomum zeylanicum essential oil (CZEO) and its antimicrobial and antibiofilm activity against Staphylococcus strains isolated from dogs with otitis. The results showed that CZEO contains (E)-cinnamaldehyde, eugenol, and (E)-cinnamyl acetate as the main compounds, and it exhibited antimicrobial and antibiofilm effects against the tested strains.
Article
Chemistry, Medicinal
Rafaela Oliveira Ferreira, Jessica Colodette Galo, Paula Monteiro Lopes, Daniela Sales Alviano Moreno, Tania Maria Sarmento da Silva, Mario Geraldo de Carvalho
Summary: This study isolated and identified bioactive compounds from Clusia nemorosa fruits and investigated their antimicrobial and antioxidant activities. The compounds, except for one, were described for the first time in this species, and showed potential in the treatment of diseases related to oxidative stress.
NATURAL PRODUCTS JOURNAL
(2022)
Article
Plant Sciences
Gisely de Lima Oliveira, Helena Regina Pinto Lima, Bruno Couto da Silva, Mario Geraldo de Carvalho, Rosane Nora de Castro, Heber dos Santos Abreu, Alexandre Monteiro de Carvalho
Summary: This study characterized the lignin in the cell wall of Euterpe oleracea Mart., finding that the stem samples had high lignin content, which decreased after treatment with NaOH. Spectroscopic and chromatographic analysis revealed the composition and structural units of GS-type lignin.
Article
Biochemistry & Molecular Biology
Francisco Erivaldo Freitas da Silva, Francisco das Chagas Lima Pinto, Otilia Deusdenia Loiola Pessoa, Aluisio Marques da Fonseca, Jose Galberto Martins da Costa, Gilvandete Maria Pinheiro Santiago
Summary: In this study, twelve campesterol derivatives were prepared and evaluated for their antibacterial activity against various bacteria. Four compounds were discovered for the first time. Molecular docking simulations were conducted to investigate the binding site of the target proteins.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Food Science & Technology
Jonathas de Souza Vieira, Vanessa Sales de Oliveira, Mara Junqueira Carneiro, Tatiana Labre da Silva, Ivanilda Maria Augusta, Mario Geraldo de Carvalho, Alexandra Christine Helena Frankland Sawaya, Tatiana Saldanha
Summary: This review comprehensively describes the phenolic compounds in pink pepper, mainly phenolic acids and flavonoids. The rich phenolic composition contributes to the extensively reported antioxidant capacity of pink pepper. The application of pink pepper fruit as a natural antioxidant has been investigated through extracts, direct addition, and the use of residues, showing promising results in reducing harmful compounds and lipid oxidation in various food matrices. Pink pepper is highlighted as an alternative to synthetic antioxidants in processed food.
Article
Biochemistry & Molecular Biology
Frances Regiane dos Santos, Sabrina Rita da Fonseca Rezende, Luan Valim dos Santos, Elaine R. M. Nery da Silva, Matheus Silva Caiado, Marco Andre Alves de Souza, Emerson Guedes Pontes, Mario Geraldo de Carvalho, Raimundo Braz Filho, Rosane Nora Castro
Summary: This study aimed to extract and characterize essential oils from Myrtaceae species and evaluate their larvicidal and fungicidal effects. The results showed that the composition and biological activities of the essential oils varied among different species.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Agronomy
Thaisa de Oliveira Silveira, Mayara de Mello Marques, Gustavo Torres dos Santos Amorim, Mario Geraldo de Carvalho, Pedro Correa Damasceno
Summary: This study characterized and classified a germplasm collection of bitter melon to assess its genetic diversity and identify genotypes of agronomic interest. The study found that the genotypes could be grouped into different clusters, with variations in fruit and seed production as well as sizes. The population showed high diversity, with higher intra-group diversity among small fruit genotypes.
Article
Agronomy
Edson Cardoso Teixeira, Almir Ribeiro de Carvalho Jr, Mario Geraldo de Carvalho, Sonia Pereira Cabrera, Tania Maria Sarmento da Silva, Rafaela Oliveira Ferreira
Summary: Leaves of Caryocar brasiliense are used in folk medicine to treat respiratory diseases. An analysis of the leaves revealed high levels of phenols and flavonoids, as well as antioxidant activity. The use of ultra-high-performance liquid chromatography and mass spectrometry allowed for the identification of several compounds, with 21 being discovered for the first time in C. brasiliense. These findings suggest that C. brasiliense may serve as a potential source of bioactive substances with antioxidant properties.
EMIRATES JOURNAL OF FOOD AND AGRICULTURE
(2022)
Article
Chemistry, Multidisciplinary
Mario Geraldo de Carvalho, Fernanda Cristina M. Rondon, Daniela Santos Carneiro-Torres, Patricia Fampa, Claudia Maria L. Bevilaqua, Paulo Nogueira Bandeira, Geovany Amorim Gomes
Summary: This study chemically characterized and tested the anti-Leishmania infantum activity of essential oils from two plant species. The results showed that these oils have potential as leishmanicidal agents.
REVISTA VIRTUAL DE QUIMICA
(2022)