期刊
PLANTA MEDICA
卷 79, 期 3-4, 页码 295-300出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0032-1328188
关键词
antioxidative activity; Coreopsis lanceolata; Compositae; phenolics; chalcones
资金
- Korean Institute of Science and Technology, Gangneung Institute [2Z03480]
Three new chalcones, 3,2'-dihydroxy-4,3'-dimethoxychalcone-4'-glucoside (1), 4'-O-(2'''-O-caffeoyl) 2',3',3,4-tetrahydroxychalcone (2), and 2',4',3-trihydroxy-3',4-dimethoxychalcone (3), along with five known phenolics, were isolated from Coreopsis lanceolata flowers. The structures of the new compounds were elucidated by extensive spectroscopic methods including NMR and MS. The three new chalcones showed a good in vitro HepG2 cell protecting effect against tert-butylhydroperoxide-induced oxidative stress.
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