期刊
PLANTA MEDICA
卷 75, 期 4, 页码 367-370出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0028-1112211
关键词
Vitex trifolia; Verbenaceae; fruits; diterpenoids; antiproliferation; cell cycle
Two new labdane-type diterpenoids vitetrifolin H (1) and vitetrifolin 1 (2), and one new monoterpenoid vitexoid (3), were isolated from the fruits of Vitex trifolia L., together with seven known diterpenoids. Structures of all compounds were elucidated by extensive spectroscopic methods. All these compounds exhibited inhibition of Hela cell proliferation, with IC50 values in the range of 4-28 mu M. In addition, vitetrifolin 1 (2) induced cell cycle G(0)/G(1) phase arrest and apoptosis of Hela cells.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据