期刊
PLANTA MEDICA
卷 74, 期 4, 页码 422-426出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2008-1034327
关键词
Erythrino abyssinica; Leguminosae; chalcones; cytotoxic activity
Four new chalcones 1-4, named abyssinones A-D, were isolated from the stem bark of the plant Erythrina abyssinica and their structures were elucidated on the basis of spectroscopic analyses. The compounds 1, 3, and 4 were found to exhibit moderate cytotoxic activity against the human colorectal cancer cell line (Caco2) with IC50 values of 13.3,15.1, and 11.1 mu M, respectively.
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