Article
Biochemistry & Molecular Biology
Fangying Liu, Hao Chen, Liu Yang, Liang You, Jianye Ju, Shujie Yang, Xiaolin Wang, Zhongsong Liu
Summary: In this study, a mapping population was constructed to identify QTL loci for seed color in rapeseed. Two QTL loci were identified, one major QTL on chromosome A09 and one minor QTL on chromosome C03. Differential expression analysis and coexpression network analysis identified candidate genes involved in flavonoid biosynthesis. This study provides a foundation for further understanding the genetic basis and regulatory mechanism of yellow seed formation in Brassica napus.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Javier Canales, Jose Verdejo, Gabriela Carrasco-Puga, Francisca M. Castillo, Anita Arenas-M, Daniel F. Calderini
Summary: This study conducted a transcriptomic analysis of the relationship between seed weight and number in two rapeseed genotypes, revealing that a reduction in the source-sink ratio induced the expression of specific gene groups related to sucrose transport, seed weight, and stress responses. Additionally, the research identified co-expression modules correlated with seed weight and negatively correlated with seed number, with a significant enrichment of transcription factors in one module. Network analysis predicted NAC transcription factors as key regulators of seed weight and number compensation in rapeseed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Multidisciplinary Sciences
Xiaorong Xing, Haidong Liu, Jingxiu Ye, Yanmei Yao, Kaixiang Li, Yanling Li, Dezhi Du
Summary: By constructing a genetic linkage map, researchers found that seed density in B. napus is associated with QTLs located on multiple chromosomes, with the cqSD-A9a QTL on chromosome A09 being stable across four environments and explaining the highest phenotypic variation. Additionally, QTL epistasis analysis revealed that seed density is controlled by both additive and epistatic effects, suggesting the importance of epistatic effects in spring B. napus. Furthermore, RNA-seq analysis of the candidate interval identified three potential candidate genes that may play a role in controlling seed density.
Article
Plant Sciences
Cuiping Zhang, Ruolin Gong, Hua Zhong, Chunyan Dai, Ru Zhang, Jungang Dong, Yangsheng Li, Shuai Liu, Jihong Hu
Summary: Rapeseed, an important source of vegetable oil and biofuel, has low yield compared to other major crops. This study identified 908 quantitative trait nucleotides related to rapeseed yield through genome-wide sequencing. Further validation of 79 candidate genes, including 12 genes affecting seed weight and seed per pod, was conducted.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Yuting Yang, Wenxiang Wang, Qiong Hu, Harsh Raman, Jia Liu
Summary: This study investigated the genetic variation and putative candidate genes of pod orientation in B. napus. Genome-wide association analysis identified two QTLs for angles of pedicel on raceme (APR) and two QTLs for angles of the pod on pedicel (APP). RNA-seq analysis revealed differentially expressed genes (DEGs) involved in pod orientation.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Lei Chen, Weixia Lei, Wangfei He, Yifan Wang, Jie Tian, Jihui Gong, Bing Hao, Xinxin Cheng, Yingjie Shu, Zhixiong Fan
Summary: Research on the flowering habit of rapeseed is important for breeding early maturing varieties. This study identified multiple quantitative trait loci (QTL) related to the days-to-flowering trait in rapeseed. Two major QTLs were identified, and several genes potentially related to flowering time were found. A marker closely linked to the flowering time trait was also developed.
Article
Plant Sciences
Jie Xiong, Kaining Hu, Nesma Shalby, Chenjian Zhuo, Jing Wen, Bin Yi, Jinxiong Shen, Chaozhi Ma, Tingdong Fu, Jinxing Tu
Summary: This study analyzed the leaf transcriptomes of strong and weak hybrid plants and their parents, and found differentially expressed genes related to plant hormone signaling and photosynthesis pathways, as well as genes related to cell size. The results suggest that these pathways play a role in regulating the dynamic changes and heterosis in hybrid plants.
Article
Agronomy
Wen Chu, Jia Liu, Hongtao Cheng, Chao Li, Li Fu, Wenxiang Wang, Hui Wang, Mengyu Hao, Desheng Mei, Kede Liu, Qiong Hu
Summary: In this study, an elite line OR88 with strong shatter resistance and a lignified-layer bridge (LLB) structure was identified in rapeseed. The LLB structure was controlled by a single recessive gene and the gene responsible for LLB was identified as BnTCP8.009. Genetic markers linked to the candidate gene were developed. This finding provides valuable insights for the development of shatter-resistant rapeseed cultivars.
Article
Genetics & Heredity
Yu Xu, Shunxian Tao, Yunlin Zhu, Qi Zhang, Ping Li, Han Wang, Yan Zhang, Aldiyar Bakirov, Hanming Cao, Mengfan Qin, Kai Wang, Yiji Shi, Xiang Liu, Lin Zheng, Aixia Xu, Zhen Huang
Summary: This study found that rapeseed line 2205 exhibited more tolerance to alkaline salt compared to line 1423, with lesser plasma membrane damage index, accumulated osmotic solute, and higher antioxidant enzyme activities contributing to its tolerance. Ultrastructure observation and transcriptome analysis revealed a more integrated mesophyll-cell structure and more genes responding to alkaline salt in line 2205. The high expression of specific-response genes enriched in carbohydrate metabolism, photosynthetic processes, ROS regulating, and response to salt stress pathways contributes to the alkaline salt tolerance. Twelve potential cross-differentially expressed genes were suggested for further analysis of the resistance mechanism of rapeseed.
Article
Agricultural Engineering
Mengna Yu, Rui Zhang, Yajun Liu, Yuan Gu, Guoxia Shang, Yonghai Fan, Miao Liu, Shengting Li, Yuqiao Tang, Chuanfang Wan, Xuli Wu, Cunmin Qu, Jiana Li, Kun Lu
Summary: This study identified a stem bending 1 (stb1) mutant in rapeseed with abnormal stem development and conducted phenotype characterization, genetic analysis, quantitative trait locus mapping, and transcriptome analysis to elucidate the molecular mechanisms involved. The down-regulated genes in the mutant were mainly related to auxin transport and coenzyme metabolism processes, suggesting defects in polar auxin transport as a potential cause for the phenotype of the stb1 mutant. These findings lay a foundation for further investigation into the molecular mechanisms of stem development in rapeseed.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Agricultural Engineering
Xiaohui Zhang, Huining Li, Jin Hu, Ying Liu, Qiyang Huang, Xiang Li, Pengfei Wang, Xianming Zhou, Guangsheng Yang
Summary: In this study, a doubled haploid population was used to identify 30 quantitative trait loci (QTLs) that affect oil content in rapeseed. One stable QTL (qOC.A10) with practical breeding significance was confirmed and used for improving oil content in rapeseed. Marker-assisted selection was successfully applied to improve the parent line, resulting in a significantly increased oil content in the improved line. Transcriptome analysis provided insights into the potential functional genes of qOC.A10. This study enhances our understanding of the genetic foundation of oil content in rapeseed and contributes to practical breeding efforts.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Agronomy
Shuangshuang Xin, Hongli Dong, Lei Yang, Dengwen Huang, Fajing Zheng, Yixin Cui, Shuang Wu, Jinghang Liao, Yajun He, Huafang Wan, Zhi Liu, Xiaorong Li, Wei Qian
Summary: Through genome-wide association analysis, the study identified SNPs and genes related to two components of seed yield in rapeseed, SNPP and SW, and found overlapping loci with the same direction of genetic effects on both components.
MOLECULAR BREEDING
(2021)
Article
Plant Sciences
Xiaohui Zhang, Xiang Li, Huining Li, Zhuanrong Wang, Rui Xia, Jin Hu, Pengfei Wang, Xianming Zhou, Lili Wan, Dengfeng Hong, Guangsheng Yang
Summary: Improving sclerotinia stem rot (SSR) resistance in rapeseed faces three challenges: limited investigation of breeding materials, linkage between SSR resistance and flowering time, and neglect of resistance loci in susceptible materials. This study mapped multiple QTLs for stem resistance, disease index, and flowering time in a doubled haploid population, and proposed a strategy for resistance improvement based on identified QTLs.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Agronomy
Yiren Qing, Yaoming Li, Lizhang Xu, Zheng Ma
Summary: The main reason for the massive loss of rapeseed in mechanized harvesting is due to the mismatch between harvester requirements and pod shatter resistance and plant characteristics. Screening varieties with higher shatter resistance and suitable features for mechanized harvesting can significantly reduce field harvest loss. This study provides valuable insights for both agronomic experts in improving rapeseed varieties and agricultural machinery experts in optimizing rapeseed harvesters.
Article
Plant Sciences
Yiran Ding, Shizhou Yu, Jia Wang, Maoteng Li, Cunmin Qu, Jiana Li, Liezhao Liu
Summary: A study comparing high-lignin and low-lignin content rapeseed offspring found correlations between lignin content and seed coat thickness, with significantly higher expression of lignin pathway genes in high-lignin seed coats. Additionally, some hormone synthesis genes and transcription factors were differentially expressed in high-lignin lines, and genes related to the flavonoid pathway were strongly expressed.
Article
Biochemistry & Molecular Biology
Jing Cai, Yue Wang, Xinfa Wang, Zihe Ai, Tianyuan Li, Xiaohong Pu, Xin Yang, Yixing Yao, Junping He, Steven Y. Y. Cheng, Tingting Yu, Chen Liu, Shen Yue
Summary: Medulloblastoma is a common malignant pediatric brain tumor, and metastasis and relapse are the leading causes of death in patients. This study reveals that AMPK inhibits the proliferation and metastasis of SHH-MB cells through the SHH-GLI1 and NF-kappa B signaling pathways. Blocking the NF-kappa B and Shh pathways together synergistically restrains the growth and invasion of SHH-MB cells, suggesting a potential molecular therapy target.
CELL AND BIOSCIENCE
(2023)
Article
Plant Sciences
Na Li, Dan Zhou, Nannan Li, Shengnan Kong, Jianli Shang, Wanting Zhu, Jiming Wang, Shuangwu Ma
Summary: In this study, it was found that at least two genes with inhibitory epistasis are responsible for the thin seed coat trait in egusi watermelon. Mapping of these genes and comparative transcriptome analysis provided valuable information for understanding the genetic mechanisms and potential candidate genes for the thin seed coat trait. These findings could also be useful for breeding purposes.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Jie Li, Yi Li, Jiangwei Qiao, Li Li, Xinfa Wang, Jian Yao, Guisheng Liao
Summary: A low-cost approach for counting rapeseed inflorescences using YOLOv5 with CBAM based on UAV RGB imagery was developed. Experimental results showed excellent counting ability and location accuracy, revealing the dynamic change in the number of rapeseed inflorescences over time. A significant positive correlation between actual crop yield and automatically obtained rapeseed inflorescence total number was identified, providing important support for breeding high-yield rapeseed varieties.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Xinfa Wang, Xianbo Zhou, Fang Wang, Nan Zhang, Yan Zhang, Zhen Ao, Fang He
Summary: This study found that long noncoding RNA (lncRNA) TPTEP1 is downregulated in diabetic retinopathy (DR). Overexpression of TPTEP1 can reduce cell viability and proliferation induced by high glucose and oxidative stress, and miR-489-3p and Nrf2 play regulatory roles in this process.
ACTA BIOCHIMICA POLONICA
(2023)
Article
Biotechnology & Applied Microbiology
Hongxia Zhu, Linfeng Hu, Tetiana Rozhkova, Xinfa Wang, Chengwei Li
Summary: This study used statistical approaches to optimize the environmental and nutritional parameters for improving the production of antifungal components by Streptomyces sp. HU2014. The results showed that two fractions, F6 and F8, from the cell-free filtrates of HU2014 culture broth were rich in antifungal compounds. Shake-flask experiments were used to evaluate and optimize different parameters, such as incubation time, temperature, agitation speed, inoculum size, initial pH, and medium composition. The validation experiment confirmed the increase in the inhibition of Rhizoctonia solani YL-3 when compared with the basal medium.
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
(2023)
Article
Immunology
Yi Xu, Jinmin Ma, Wenjie Ouyang, Rosary Sin Yu Yao, Wei Cao, Jiandong Li, Rongrong Zou, Chunxiao Fang, Fansen Zeng, Fengxia Yang, Xinfa Wang, Jing Yuan, Huimin Xia, Hui Wang, Sitang Gong, Yingxia Liu
Summary: Hand, foot, and mouth disease (HFMD) is a common children infectious disease caused by human enteroviruses. The immune response to the virus infection may lead to differences in disease severity. By studying the transcriptomes of peripheral blood mononuclear cells, it was found that immune pathways were up-regulated in patients with mild symptoms but down-regulated in patients with severe symptoms. Based on these findings, models for predicting severe HFMD were developed.
CLINICAL IMMUNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Jiang Ye, Huabing Liang, Xueyang Zhao, Na Li, Dongji Song, Jiepeng Zhan, Xinfa Wang, Jinxing Tu, Rajeev Kumar Varshney, Jiaqin Shi, Hanzhong Wang
Summary: Heterosis refers to the better performance of cross progeny compared with inbred parents, and its utilization contributes greatly to agricultural production. Several hypotheses have been proposed to explain heterosis mainly including dominance, over-dominance (or pseudo-overdominance) and epistasis. However, systematic dissection and verification of these hypotheses are rarely documented.
PLANT BIOTECHNOLOGY JOURNAL
(2023)
Article
Chemistry, Analytical
Xinfa Wang, Zhenwei Wu, Meng Jia, Tao Xu, Canlin Pan, Xuebin Qi, Mingfu Zhao
Summary: Due to the limitations of computer power and the complexity of the plant factory environment, the precision of small-target detection for tomatoes in real-world applications is inadequate. Therefore, an improved SM-YOLOv5 detection algorithm and model based on YOLOv5 are proposed for target detection by tomato-picking robots in plant factories. The improved model achieved a higher mAP and had a lighter weight compared to the YOLOv5 baseline model.
Article
Multidisciplinary Sciences
Tao Xu, Weishuo Zhao, Lei Cai, Xiaoli Shi, Xinfa Wang
Summary: This paper proposes a lightweight saliency detection algorithm for real-time localization of livestock meat bones. It constructs a lightweight feature extraction network based on multi-scale attention to extract more adequate salient object features. The fusion of jump connections is introduced to capture fine-grained semantics and coarse-grained semantics at full scale. Experimental results show that the proposed method achieves first-class detection accuracy with 40 times fewer parameters than the conventional model.
SCIENTIFIC REPORTS
(2023)
Article
Plant Sciences
Zhengshu Tian, Xinfa Wang, Xiaoling Dun, Ze Tian, Xiaoxue Zhang, Jinfeng Li, Lijun Ren, Jinxing Tu, Hanzhong Wang
Summary: In this study, it was found that high stem mechanical strength is the main factor determining the superior lodging resistance of the rapeseed variety ZS11. The anatomical analysis showed that ZS11 possessed thicker xylem layers and denser interfascicular fibrocytes, and the analysis of cell wall components revealed that ZS11 had more lignin and cellulose during stem secondary development. The comparative transcriptome analysis further revealed the increased expression of genes associated with lignin biosynthesis pathway in ZS11.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Oncology
Rui Zhang, Yanfang Peng, Zhe Gao, Jing Qian, Kang Yang, Xinfa Wang, Wenjing Lu, Yongjie Zhu, Dezhi Qiu, Tong Jin, Gang Wang, Junping He, Ning Liu
Summary: This study found that E twenty-six variant transcription factor 4 (ETV4) is significantly upregulated in multiple cancers and is associated with poor survival outcomes. ETV4 expression is also correlated with immune cell infiltration, tumor heterogeneity, mismatch repair gene expression, DNA methylation, and tumor stemness. Additionally, ETV4 expression seems to affect sensitivity to several anticancer drugs.
FRONTIERS IN ONCOLOGY
(2023)
Article
Multidisciplinary Sciences
Zhen-wei Wu, Ming-hao Liu, Cheng-xiu Sun, Xin-fa Wang
Summary: Plant factories are advanced facilities for efficient plant cultivation. Tomato cultivation in plant factories has economic and agricultural value, but manual operations are still needed. In order to address this issue, a tomato fruit dataset named TomatoPlantfactoryDataset was constructed for various tasks, and it is publicly available for research and communication purposes.
Article
Food Science & Technology
Xinfa Wang, Viktor Onychko, Vladislav Zubko, Zhenwei Wu, Mingfu Zhao
Summary: In recent years, innovative sustainable agricultural production technologies such as vertical farms and plant factories have been rapidly developing worldwide. However, the recognition and satisfaction from the government, producers, sales companies, and consumers are low due to various factors. This study conducted a questionnaire to understand the level of awareness, purchase intentions, and consumption expectations of respondents towards this new agricultural production system.
FRONTIERS IN SUSTAINABLE FOOD SYSTEMS
(2023)
Article
Horticulture
Na Li, Shengnan Kong, Dan Zhou, Nannan Li, Jianli Shang, Jiming Wang, Shuangwu Ma
Summary: This study constructed three segregation populations to locate and fine map a new quantitative trait locus (QTL) for fruit size in watermelon. It was found that fruit size in watermelon is controlled by a single recessive gene. Through high-density genetic linkage mapping and DNA sequencing, a significant QTL associated with fruit size was identified on chromosome 8. Candidate genes related to fruit size were successfully identified.
SCIENTIA HORTICULTURAE
(2023)
Article
Agricultural Engineering
Qihang Liu, Xinfa Wang, Mingfu Zhao, Tao Liu
Summary: This study investigated the influence of yellow, green, and proportional yellow-green light on the capture effect of western flower thrips. The results showed that the capture effect was optimal when the average night temperature was 27 degrees C. Green light intensified the sensitivity to yellow-green light, while yellow light inhibited it.
INTERNATIONAL JOURNAL OF AGRICULTURAL AND BIOLOGICAL ENGINEERING
(2023)
Article
Biotechnology & Applied Microbiology
Xue-Mei Yang, Jing-Hao Zhao, Xiao-Yu Xiong, Zhang-Wei Hu, Ji-Fen Sun, Hao Su, Yan-Jing Liu, Ling Xiang, Yong Zhu, Jin-Lu Li, Sadam Hussain Bhutto, Guo-Bang Li, Shi-Xin Zhou, Chi Li, Mei Pu, He Wang, Zhi-Xue Zhao, Ji-Wei Zhang, Yan-Yan Huang, Jing Fan, Wen-Ming Wang, Yan Li
Summary: The Arabidopsis RPW8.1 gene enhances disease resistance but compromises plant growth. It has been found that RPW8.1 constitutively enhances the expression of WRKY51 transcription factor and activates salicylic acid and ethylene signaling pathways. WRKY51, in turn, suppresses RPW8.1 expression, forming a feedback regulation loop.
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Hannes Claeys, Eveline Neyrinck, Lies Dumoulin, Anne Pharazyn, Arne Verstichele, Laurens Pauwels, Michael L. Nuccio, Frederic Van Ex
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Melanie Ormancey, Bruno Guillotin, Camille Ribeyre, Clemence Medina, Nathanael Jariais, Helene San Clemente, Patrice Thuleau, Serge Plaza, Martina Beck, Jean-Philippe Combier
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Edgar Perez-Matas, Diego Hidalgo-Martinez, Elisabeth Moyano, Javier Palazon, Mercedes Bonfill
Summary: In this study, the production of paclitaxel was enhanced by overexpressing the bottleneck genes BAPT and DBTNBT in Taxus baccata cells. The transgenic cells showed significantly higher expression of these genes and improved taxane production compared to the wild type. Transcriptional profiling revealed that the GGPPS, TXS, and DBAT genes were most responsive to DBTNBT overexpression and the dual elicitation treatment.
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Biying Dong, Dong Meng, Zhihua Song, Hongyan Cao, Tingting Du, Meng Qi, Shengjie Wang, Jingyi Xue, Qing Yang, Yujie Fu
Summary: This study identified the involvement of the citrate transporter CcMATE35 and the long noncoding RNA CcLTCS in aluminum stress response in pigeon pea. These findings suggest that the modules CcNFYB3-CcMATE35 and CcLTCS-CcCS jointly regulate the efflux and synthesis of citrate to enhance the resistance of pigeon pea under aluminum stress.
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Review
Biotechnology & Applied Microbiology
Tien V. Vu, Ngan Thi Nguyen, Jihae Kim, Jong Chan Hong, Jae-Yean Kim
Summary: Prime editing technology uses an extended guide RNA to direct a fusion peptide to a specific location in the genome, enabling precise gene editing. This groundbreaking tool has potential in improving crop varieties, but efficiency limitations exist in certain plants.
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Yan Xu, Jinyi Tan, Junxing Lu, Yuelin Zhang, Xin Li
Summary: Sclerotinia sclerotiorum causes white mold in economically important plants, and the discovery of SsGAP1 and SsRAS1/SsRAS2 genes as essential regulators of fungal development and virulence provides potential targets for controlling the disease.
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Xiaoyang Chen, Chen Liu, Hailin Wang, Qi Liu, Yaping Yue, Yuhang Duan, Zhaoyun Wang, Lu Zheng, Xiaolin Chen, Yaohui Wang, Junbin Huang, Qiutao Xu, Yuemin Pan
Summary: This study identified a secreted protein, Uv1809, as a key virulence factor in Ustilaginoidea virens-rice interactions. Uv1809 inhibits rice immunity and promotes infection by targeting and enhancing rice histone deacetylase OsSRT2-mediated histone deacetylation. CRISPR-Cas9 edited ossrt2 mutants showed broad-spectrum resistance to rice pathogens, indicating its potential as a genetic resource for breeding disease resistance.
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Weishuai Bi, Jing Liu, Yuanyuan Li, Ziwei He, Yongming Chen, Tingting Zhao, Xiangxiu Liang, Xiaodan Wang, Xiangzong Meng, Daolong Dou, Guangyuan Xu
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Shengjie You, Yu Wu, Wen Li, Xiaofeng Liu, Qinlan Tang, Fengkun Huang, Yan Li, Hsihua Wang, Mingchun Liu, Yang Zhang
Summary: In this study, a transcription factor called SlERF.G3-Like in tomato was found to play a role in regulating ethylene synthesis, cell wall degradation, and the flavonoid pathway. The researchers also discovered the interaction between SlERF.G3-Like and the master ripening regulator SlRIN, and increased the production of resveratrol derivatives through genetic manipulation. These findings provide insights into the coordination of fruit maturation and metabolic changes in tomatoes, and have implications for metabolic engineering.
PLANT BIOTECHNOLOGY JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Thomas R. Aalders, Mara de Sain, Fleur Gawehns, Nina Oudejans, Yoran D. Jak, Henk L. Dekker, Martijn Rep, Harrold A. van den Burg, Frank L. W. Takken
Summary: The TPL1 and TPL2 genes in tomato are closely associated with susceptibility to Fusarium wilt disease, and mutating these genes can enhance plant resistance to the disease.
PLANT BIOTECHNOLOGY JOURNAL
(2024)
