期刊
PLACENTA
卷 31, 期 12, 页码 1116-1119出版社
W B SAUNDERS CO LTD
DOI: 10.1016/j.placenta.2010.09.012
关键词
Histiocyte; Monocyte; Placenta pathology; Chronic histiocytic intervillositis; Massive perivillous histiocytosis; Assisted reproduction therapy
Chronic histiocytic intervillositis of the placenta (CHI) is a rare and poorly understood pathology which may occur in all trimesters. The most conspicuous feature is a histiocytic infiltration of the intervillous space without involvement of the villous parenchyma. In this report on CHI, we re-evaluate a series of four cases and focus on histological, immunohistological and fluorescence in situ hybridisation-derived findings, fetal status and clinical data for previously unrecognised CHI-associated features. Our approach revealed that assisted reproduction-induced pregnancy had been performed in 2 of 4 CHI cases, but other factors and comorbidities are likely to contribute to CHI. (C) 2010 Elsevier Ltd. All rights reserved.
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