Inhibition of mutant BRAF splice variant signaling by next-generation, selective RAF inhibitors
出版年份 2014 全文链接
标题
Inhibition of mutant BRAF splice variant signaling by next-generation, selective RAF inhibitors
作者
关键词
-
出版物
Pigment Cell & Melanoma Research
Volume 27, Issue 3, Pages 479-484
出版商
Wiley
发表日期
2014-01-15
DOI
10.1111/pcmr.12218
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- In Vivo MAPK Reporting Reveals the Heterogeneity in Tumoral Selection of Resistance to RAF Inhibitors
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- RASMutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors
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- RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
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- RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
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- Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
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- PLX4032, a selective BRAFV600E kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAFWT melanoma cells
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