标题
Biology of advanced uveal melanoma and next steps for clinical therapeutics
作者
关键词
-
出版物
Pigment Cell & Melanoma Research
Volume 28, Issue 2, Pages 135-147
出版商
Wiley
发表日期
2014-08-12
DOI
10.1111/pcmr.12304
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- A phase I trial of ipilimumab plus bevacizumab in patients with unresectable stage III or stage IV melanoma.
- (2017) F. S. Hodi et al. JOURNAL OF CLINICAL ONCOLOGY
- Activity of cabozantinib (XL184) in soft tissue and bone: Results of a phase II randomized discontinuation trial (RDT) in patients (pts) with advanced solid tumors.
- (2017) M. S. Gordon et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II study of selumetinib (sel) versus temozolomide (TMZ) in gnaq/Gna11 (Gq/11) mutant (mut) uveal melanoma (UM).
- (2017) Richard D. Carvajal et al. JOURNAL OF CLINICAL ONCOLOGY
- The Molecular Pathology of Melanoma: An Integrated Taxonomy of Melanocytic Neoplasia
- (2014) Boris C. Bastian Annual Review of Pathology-Mechanisms of Disease
- Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
- (2014) Xiaodong Feng et al. CANCER CELL
- Modulation of the Tumor Cell Phenotype by IFN- Results in Resistance of Uveal Melanoma Cells to Granule-Mediated Lysis by Cytotoxic Lymphocytes
- (2014) K. Hallermalm et al. JOURNAL OF IMMUNOLOGY
- Surrogate endpoints for overall survival in metastatic melanoma: a meta-analysis of randomised controlled trials
- (2014) Keith T Flaherty et al. LANCET ONCOLOGY
- The Phosphoinositide 3-Kinase Selective Inhibitor BYL719 Enhances the Effect of the Protein Kinase C Inhibitor AEB071 in GNAQ/GNA11-Mutant Uveal Melanoma Cells
- (2014) E. Musi et al. MOLECULAR CANCER THERAPEUTICS
- Ipilimumab in pretreated metastastic uveal melanoma patients. Results of the Dutch Working group on Immunotherapy of Oncology (WIN-O)
- (2013) Sander Kelderman et al. ACTA ONCOLOGICA
- Efficacy and safety of ipilimumab in patients with pre-treated, uveal melanoma
- (2013) M. Maio et al. ANNALS OF ONCOLOGY
- BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma
- (2013) Katie A Matatall et al. BMC CANCER
- Clinical activity of ipilimumab for metastatic uveal melanoma
- (2013) Jason J. Luke et al. CANCER
- Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy
- (2013) Felix Klug et al. CANCER CELL
- Inhibition of both BRAF and MEK in BRAFV600E mutant melanoma restores compromised dendritic cell (DC) function while having differential direct effects on DC properties
- (2013) Patrick A. Ott et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Kinase inhibitors and immune check-point blockade for the treatment of metastatic melanoma and advanced cancer: synergistic or antagonistic?
- (2013) Jason John Luke et al. EXPERT OPINION ON PHARMACOTHERAPY
- Hypoxia inducible factor pathway inhibitors as anticancer therapeutics
- (2013) Sarah K Burroughs et al. Future Medicinal Chemistry
- Selumetinib plus dacarbazine versus placebo plus dacarbazine as first-line treatment for BRAF-mutant metastatic melanoma: a phase 2 double-blind randomised study
- (2013) Caroline Robert et al. LANCET ONCOLOGY
- Inhibition of Mutant GNAQ Signaling in Uveal Melanoma Induces AMPK-Dependent Autophagic Cell Death
- (2013) G. Ambrosini et al. MOLECULAR CANCER THERAPEUTICS
- Crizotinib, a c-Met Inhibitor, Prevents Metastasis in a Metastatic Uveal Melanoma Model
- (2013) O. Surriga et al. MOLECULAR CANCER THERAPEUTICS
- Circulating immune cell and microRNA in patients with uveal melanoma developing metastatic disease
- (2013) Susan Achberger et al. MOLECULAR IMMUNOLOGY
- Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3
- (2013) Marcel Martin et al. NATURE GENETICS
- Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma
- (2013) J William Harbour et al. NATURE GENETICS
- Nivolumab plus Ipilimumab in Advanced Melanoma
- (2013) Jedd D. Wolchok et al. NEW ENGLAND JOURNAL OF MEDICINE
- SF3B1 Mutations Are Associated with Alternative Splicing in Uveal Melanoma
- (2013) S. J. Furney et al. Cancer Discovery
- Structure–activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway inhibitor and anti-cancer agent
- (2012) Jiyoung Mun et al. BIOORGANIC & MEDICINAL CHEMISTRY
- The MEK1/2 inhibitor, selumetinib (AZD6244; ARRY-142886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models
- (2012) S V Holt et al. BRITISH JOURNAL OF CANCER
- Arylsulfonamide KCN1 Inhibits In Vivo Glioma Growth and Interferes with HIF Signaling by Disrupting HIF-1 Interaction with Cofactors p300/CBP
- (2012) S. Yin et al. CLINICAL CANCER RESEARCH
- Combination Small Molecule MEK and PI3K Inhibition Enhances Uveal Melanoma Cell Death in a Mutant GNAQ- and GNA11-Dependent Manner
- (2012) J. S. Khalili et al. CLINICAL CANCER RESEARCH
- Identification of Unique MEK-Dependent Genes in GNAQ Mutant Uveal Melanoma Involved in Cell Growth, Tumor Cell Invasion, and MEK Resistance
- (2012) G. Ambrosini et al. CLINICAL CANCER RESEARCH
- New Strategies in Pleural Mesothelioma: BAP1 and NF2 as Novel Targets for Therapeutic Development and Risk Assessment
- (2012) M. Ladanyi et al. CLINICAL CANCER RESEARCH
- Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
- (2012) Y. Liu-Chittenden et al. GENES & DEVELOPMENT
- Design and in Vitro Activities of N-Alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, Novel, Small-Molecule Hypoxia Inducible Factor-1 Pathway Inhibitors and Anticancer Agents
- (2012) Jiyoung Mun et al. JOURNAL OF MEDICINAL CHEMISTRY
- c-Met, epidermal growth factor receptor, and insulin-like growth factor-1 receptor are important for growth in uveal melanoma and independently contribute to migration and metastatic potential
- (2012) Xinqi Wu et al. MELANOMA RESEARCH
- A pilot study of sunitinib malate in patients with metastatic uveal melanoma
- (2012) Amit Mahipal et al. MELANOMA RESEARCH
- Ipilimumab activity in advanced uveal melanoma
- (2012) Muhammad Adnan Khattak et al. MELANOMA RESEARCH
- Protein Kinase C Inhibitor AEB071 Targets Ocular Melanoma Harboring GNAQ Mutations via Effects on the PKC/Erk1/2 and PKC/NF- B Pathways
- (2012) X. Wu et al. MOLECULAR CANCER THERAPEUTICS
- A Genome-wide RNAi Screen Reveals a Trio-Regulated Rho GTPase Circuitry Transducing Mitogenic Signals Initiated by G Protein-Coupled Receptors
- (2012) Jose P. Vaqué et al. MOLECULAR CELL
- The Protein Kinase C Inhibitor Enzastaurin Exhibits Antitumor Activity against Uveal Melanoma
- (2012) Xinqi Wu et al. PLoS One
- KCN1, a Novel Synthetic Sulfonamide Anticancer Agent: In Vitro and In Vivo Anti-Pancreatic Cancer Activities and Preclinical Pharmacology
- (2012) Wei Wang et al. PLoS One
- Phase II Trial of Sorafenib in Combination with Carboplatin and Paclitaxel in Patients with Metastatic Uveal Melanoma: SWOG S0512
- (2012) Shailender Bhatia et al. PLoS One
- Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation
- (2012) A. Dey et al. SCIENCE
- Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor
- (2012) Qi Shi et al. ACS Medicinal Chemistry Letters
- Influence of CD8+ T regulatory cells on intraocular tumor development
- (2012) Kyle C. McKenna et al. Frontiers in Immunology
- Good news–bad news: the Yin and Yang of immune privilege in the eye
- (2012) John V. Forrester et al. Frontiers in Immunology
- Ocular Immune Privilege and Ocular Melanoma: Parallel Universes or Immunological Plagiarism?
- (2012) Jerry Y. Niederkorn Frontiers in Immunology
- Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors
- (2011) Chalet Tan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Histone Deacetylase Inhibitors Induce Growth Arrest and Differentiation in Uveal Melanoma
- (2011) S. Landreville et al. CLINICAL CANCER RESEARCH
- Aflibercept (VEGF Trap) in Inoperable Stage III or Stage IV Melanoma of Cutaneous or Uveal Origin
- (2011) A. A. Tarhini et al. CLINICAL CANCER RESEARCH
- Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers
- (2011) M. H. Abdel-Rahman et al. JOURNAL OF MEDICAL GENETICS
- Design and Synthesis of Novel Small-Molecule Inhibitors of the Hypoxia Inducible Factor Pathway
- (2011) Suazette Reid Mooring et al. JOURNAL OF MEDICINAL CHEMISTRY
- Germline mutations in BAP1 predispose to melanocytic tumors
- (2011) Thomas Wiesner et al. NATURE GENETICS
- Germline BAP1 mutations predispose to malignant mesothelioma
- (2011) Joseph R Testa et al. NATURE GENETICS
- Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma
- (2010) Jo Eyles et al. JOURNAL OF CLINICAL INVESTIGATION
- In Aged Mice, Outgrowth of Intraocular Melanoma Depends on Proangiogenic M2-Type Macrophages
- (2010) L. V. Ly et al. JOURNAL OF IMMUNOLOGY
- Phase 2 open-label study of weekly docosahexaenoic acid–paclitaxel in patients with metastatic uveal melanoma
- (2010) Jade Homsi et al. MELANOMA RESEARCH
- Mutations inGNA11in Uveal Melanoma
- (2010) Catherine D. Van Raamsdonk et al. NEW ENGLAND JOURNAL OF MEDICINE
- Influence of Immune Privilege on Ocular Tumor Development
- (2010) Kyle C. McKenna et al. OCULAR IMMUNOLOGY AND INFLAMMATION
- Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
- (2010) J. W. Harbour et al. SCIENCE
- Defining the Human Deubiquitinating Enzyme Interaction Landscape
- (2009) Mathew E. Sowa et al. CELL
- Guidelines for the Evaluation of Immune Therapy Activity in Solid Tumors: Immune-Related Response Criteria
- (2009) J. D. Wolchok et al. CLINICAL CANCER RESEARCH
- Receptors for the liver synthesized growth factors IGF-1 and HGF/SF in uveal melanoma: intercorrelation and prognostic implications
- (2008) Mario A. Economou et al. ACTA OPHTHALMOLOGICA
- O-Mel-Inib: A Cancéro-pôle Nord-Ouest multicenter phase II trial of high-dose Imatinib mesylate in metastatic uveal melanoma
- (2008) Nicolas Penel et al. INVESTIGATIONAL NEW DRUGS
- Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis
- (2008) Shu-Hong Chang et al. MELANOMA RESEARCH
- Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
- (2008) Catherine D. Van Raamsdonk et al. NATURE
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