Kava and Kava Hepatotoxicity: Requirements for Novel Experimental, Ethnobotanical and Clinical Studies Based on a Review of the Evidence

Herbal hepatotoxicity by kava: Update on pipermethystine, flavokavain B, and mould hepatotoxins as primarily assumed culprits

(2011) Rolf Teschke et al.   DIGESTIVE AND LIVER DISEASE

Simultaneous determination of aflatoxins B1, B2, G1, G2, M1 and M2 in peanuts and their derivative products by ultra-high-performance liquid chromatography–tandem mass spectrometry

(2010) Baifen Huang et al.   ANALYTICA CHIMICA ACTA

Development and validation of a LC–MS/MS method for the simultaneous determination of aflatoxins, dyes and pesticides in spices

(2010) C. Ferrer Amate et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Kava: A Comprehensive Review of Efficacy, Safety, and Psychopharmacology

(2010) Jerome Sarris et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Kava, the anxiolytic herb: back to basics to prevent liver injury?

(2010) Rolf Teschke et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways

(2010) Ping Zhou et al.   FASEB JOURNAL

Risk of Kava Hepatotoxicity and the FDA Consumer Advisory

(2010) Rolf Teschke et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

ORIGINAL ARTICLE: Kava hepatotoxicity: comparative study of two structured quantitative methods for causality assessment

(2010) R. Teschke et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Determination of aflatoxins B1, B2, G1, G2 and ochratoxin A in animal feed by ultra high-performance liquid chromatography-tandem mass spectrometry

(2010) Sergio José López Grío et al.   JOURNAL OF SEPARATION SCIENCE

Kava hepatotoxicity: pathogenetic aspects and prospective considerations

(2010) Rolf Teschke   LIVER INTERNATIONAL

FT-IR Spectroscopy for Rapid Differentiation of Aspergillus flavus, Aspergillus fumigatus, Aspergillus parasiticus and Characterization of Aflatoxigenic Isolates Collected from Agricultural Environments

(2010) David Garon et al.   MYCOPATHOLOGIA

Kava hepatotoxicity solution: A six-point plan for new kava standardization

(2010) Rolf Teschke et al.   PHYTOMEDICINE

Does inflammation play a role in kava hepatotoxicity?

(2010) Lillian Yuan Zhang et al.   PHYTOTHERAPY RESEARCH

Re-introduction of Kava(Piper methysticum)to the EU: Is There a Way Forward?

(2010) Jerome Sarris et al.   PLANTA MEDICA

Regulatory causality evaluation methods applied in kava hepatotoxicity: Are they appropriate?

(2010) Rolf Teschke et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Mycotoxins and human disease: a largely ignored global health issue

(2009) C. P. Wild et al.   CARCINOGENESIS

Time for a reassessment of the use of Kava in anxiety?

(2009) J. Sarris et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Kava hepatotoxicity: Regulatory data selection and causality assessment

(2009) R. Teschke et al.   DIGESTIVE AND LIVER DISEASE

Gene expression profiling in male B6C3F1 mouse livers exposed to kava identifies – Changes in drug metabolizing genes and potential mechanisms linked to kava toxicity

(2009) Lei Guo et al.   FOOD AND CHEMICAL TOXICOLOGY

Development of a Novel Immunoaffinity Column for Aflatoxin Analysis Using an Organic Solvent-Tolerant Monoclonal Antibody

(2009) Mikiko Uchigashima et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Kava and St. John's Wort: Current Evidence for Use in Mood and Anxiety Disorders

(2009) Jerome Sarris et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Determination of aflatoxins in cereal flours by solid-phase microextraction coupled with liquid chromatography and post-column photochemical derivatization-fluorescence detection

(2009) M. Quinto et al.   JOURNAL OF CHROMATOGRAPHY A

Kava hepatotoxicity: Comparison of aqueous, ethanolic, acetonic kava extracts and kava–herbs mixtures

(2009) Rolf Teschke et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Kava Anxiety Depression Spectrum Study (KADSS): a randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticum

(2009) J. Sarris et al.   PSYCHOPHARMACOLOGY

Causality assessment in hepatotoxicity by drugs and dietary supplements

(2008) Rolf Teschke et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Nekrotisierende Hepatitis nach Einnahme pflanzlicher Heilmittel

(2008) S. Strahl et al.   DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT

Kava hepatotoxicity: a clinical survey and critical analysis of 26 suspected cases

(2008) Rolf Teschke et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

High dose of commercial products of kava (Piper methysticum) markedly enhanced hepatic cytochrome P450 1A1 mRNA expression with liver enlargement in rats

(2008) Yuko Yamazaki et al.   FOOD AND CHEMICAL TOXICOLOGY

Development and Application of Solvent-free Extraction for the Detection of Aflatoxin M1in Dairy Products by Enzyme Immunoassay

(2008) Laura Anfossi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Quantification of Kavalactones and Determination of Kava (Piper methysticum) Chemotypes Using Near-Infrared Reflectance Spectroscopy for Quality Control in Vanuatu

(2008) Privat Lasme et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL

Hepatocellular toxicity of kava leaf and root extracts

(2007) Saskia Lüde et al.   PHYTOMEDICINE