Article
Chemistry, Medicinal
Antonella Delicato, Marco Masi, Francisco de Lara, Diego Rubiales, Ida Paolillo, Valeria Lucci, Geppino Falco, Viola Calabro, Antonio Evidente
Summary: This manuscript reports the isolation and identification of compounds from C. phelypaea and their potential applications in antioxidant activity and cell proliferation and differentiation. The results showed that these compounds have strong antioxidant potential and can preserve cell proliferation and stem cell characteristics, which are important for tissue engineering and regenerative medicine.
PHYTOTHERAPY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Miwa Kubo, Ryo Irimajiri, Mitsuki Kawata, Yuta Takahashi, Kana Hayashi, Michiyo Matsuno, Kenichi Harada, Norihito Ikui, Hajime Mizukami, Nobuo Kawahara, Yoshiyasu Fukuyama
Summary: A MeOH extract from Gmelina arborea Roxb. ex Sm. (Lamiaceae) stem showed neurite outgrowth-promoting activity in NGF-mediated PC12 cells. Eight previously undescribed prenylated coumarin compounds and nine known compounds were isolated through bioassay-guided fractionation. Structural elucidation of these compounds was achieved through extensive spectroscopic analysis, literature comparison, and chemical reactions. Prenylated coumarin compounds from G. arborea were discovered for the first time, among which N-methylflindersine and artanin showed neurite outgrowth-promoting activity in NGF-mediated PC12 cells.
Article
Construction & Building Technology
Stanley Emeka Iwuoha, Werner Seim, Jonathan C. Onyekwelu
Summary: The study conducted an extensive research on the mechanical properties of Gmelina arborea and found that its material properties compare well with those of European softwood species, showing good potential as a construction material.
CONSTRUCTION AND BUILDING MATERIALS
(2021)
Article
Chemistry, Organic
Yihan Yang, Yanan Wu, Yibin Zhuang, Tao Liu
Summary: In this study, three glycosyltransferases involved in the biosynthesis of a complex acylated phenolic glycoside in Ligustrum robustum were characterized. These enzymes expand the toolbox for synthesizing natural products with various sugar chains.
Article
Chemistry, Analytical
Jieying Lai, Lichuang Huang, Yini Bao, Lu Wang, Qiang Lyu, Haodan Kuang, Kuilong Wang, Xianan Sang, Qiao Yang, Qiyuan Shan, Gang Cao
Summary: Natural products are an important source for drug discovery, but their identification is challenging due to their complexity. In this study, a deep clustering-based MS data visualization strategy, integrated with an automatic MS annotation platform and in vivo and in vitro methods, was developed to screen and validate potential lead compounds from natural products. This approach not only accelerates the discovery of lead compounds, but also sheds light on traditional processing theories.
Article
Plant Sciences
Ludovico Formenti, Veronica Caggia, Jeremy Puissant, Tim Goodall, Gaetan Glauser, Robert Griffiths, Sergio Rasmann
Summary: This research found that while climatic conditions predominantly influenced plant growth, root-associated microbes (RAMs) could also affect biomass accumulation and chemical defence expression. In low elevation areas, RAMs enhanced both plant biomass accumulation and the production of toxic secondary metabolites.
JOURNAL OF ECOLOGY
(2021)
Article
Forestry
Samuel Oluyinka Olaniran, Sophie Loening, Andreas Buschalsky, Holger Militz
Summary: The research showed that liquid uptake and penetration in gmelina wood are low, making impregnation of chemicals into its microstructure next to impossible. Therefore, alternative treatment methods should be sought to enhance its durability.
Article
Multidisciplinary Sciences
Smitha Chandrasekharan, Gandhimathi Chinnasamy, Somika Bhatnagar
Summary: This study aimed to fabricate silver nanoparticles from Gmelina arborea logging residue and found that the resulting nanoparticles exhibited enhanced antibacterial, antibiofilm, antioxidant, and wound healing properties. The eco-friendly approach presents a novel alternative for antibacterial treatments.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Ozan Oztunc, Gaye Sumer Okkali, Sevda Zeinali, Ayse Nalbantsoy, Nazli Boke Sarikahya
Summary: Four new triterpene saponins and three new prosapogenins were isolated from Cephalaria speciosa. These compounds showed significant cytotoxicity and immunomodulatory potential on macrophage cells.
SCIENTIFIC REPORTS
(2023)
Article
Agricultural Engineering
Jin Huang, Yu Peng, Zhuofan Ji, Limin Guo, Jianxiong Hao, Zhentao Zhang, Dandan Zhao
Summary: This study evaluated the drying characteristics of Cistanche deserticola with different pretreatments and revealed the degradation mechanism of phenylethanoid glycoside during drying. The results showed that microwave pretreatment promoted the drying characteristics and inhibited the degradation of phenylethanoid glycoside.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Review
Chemistry, Medicinal
Xiu-Yu Tian, Mao-Xing Li, Tong Lin, Yan Qiu, Yu-Ting Zhu, Xiao-Lin Li, Wen-Di Tao, Peng Wang, Xiao-Xia Ren, Li-Ping Chen
Summary: Phenylethanoid glycosides are compounds consisting of phenylethyl alcohol, caffeic acid, and glycosyl moieties, with significant bioactivities such as antibacterial, antitumor, and antioxidant properties. Studies over the past few decades have focused on isolating, extracting, determining, and evaluating the pharmacological activities of these natural compounds.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Biology
Maged S. Abdel-Kader, Saleh I. Alqasoumi
Summary: Chronic liver disease is a significant global health issue, with most available drugs for improving liver conditions being of natural origin. More research is needed to discover more effective drugs. This study identified nine active molecules in the plant extract, including four new compounds.
Article
Biochemistry & Molecular Biology
Li Yang, Huang Zeng, Xiaoyi Xia, Huilei Wang, Boyuan Zhao, Junwei He
Summary: In this study, three new diuretic compounds were isolated from Lagopsis supina and their diuretic activities and mechanisms were explored. The compounds were found to have acute and prolonged diuretic effects without affecting urinary pH and electrolyte balance. They also reduced the levels of certain hormones and proteins and increased the level of atriopeptin. Molecular docking studies revealed the potential binding modes of these compounds with their target proteins.
BIOORGANIC CHEMISTRY
(2022)
Article
Acoustics
K. O. Olaoye
Summary: This study presents an appropriate timbre harmonic model for measuring sound harmony using sound timbre from Gmelina arborea wood. The longitudinal free vibration method and multiple frequency observations were used to establish an integrity and harmony evaluation model successfully.
Article
Biochemistry & Molecular Biology
Meng Yang, Zhiyou Hao, Xiaolan Wang, Shiqi Zhou, Denghui Zhu, Ying Yang, Junjun Wei, Meng Li, Xiaoke Zheng, Weisheng Feng
Summary: In this study, four previously undescribed iridoid glycosides were isolated from Cornus officinalis fruit. They were found to have significant antidiabetic activities in insulin-induced insulin-resistant HepG2 cells, with compounds 1, 3, and 7 exhibiting the most potent activity.
Review
Plant Sciences
Nilufar Z. Mamadalieva, Davlat Kh. Akramov, Ludger A. Wessjohann, Hidayat Hussain, Chunlin Long, Komiljon Sh. Tojibaev, Elham Alshammari, Mohamed L. Ashour, Michael Wink
Summary: The genus Lagochilus, native to Asia, has been used as herbal medicines for thousands of years with diverse traditional uses. More than 150 secondary metabolites have been reported from Lagochilus species, exhibiting various pharmacological activities.
Article
Chemistry, Applied
Binsheng Luo, Kunhui Huang, Xianjin Sui, Miaomiao Wang, Chunlin Long
Summary: Three new xanthone glycosides and three known compounds were isolated and identified from the ethanol extract of Canscora lucidissima. Among them, compound 6 was isolated for the first time. Five compounds showed moderate antioxidant and NO inhibitory activities, with significant effects observed in Canlucosides B and C for antioxidant activity and Canlucoside B for NO inhibitory effect.
NATURAL PRODUCT RESEARCH
(2022)
Article
Biodiversity Conservation
Mingjing Zhu, Binsheng Luo, Ben La, Ruijie Chen, Fenggui Liu, Chunlin Long
Summary: The Salar people, a Turkic-speaking Islamic ethnic group in China, are skilled in horticulture and maintain diverse plant species in their homegardens, contributing significantly to local livelihood and ecosystem services.
JOURNAL OF ETHNOBIOLOGY AND ETHNOMEDICINE
(2021)
Article
Plant Sciences
Qi-Yi Lei, Jiang-Ju Zhou, Yong Xiong, Wen-Hua Zhang, Jing Luo, Chun-Lin Long
Summary: The genetic diversity of rice germplasm is crucial for improving yield and quality, especially in underdeveloped indigenous areas. This study conducted in-depth evaluation of Kam fragrant glutinous rice germplasm resources in southeast Guizhou and found a wide variety of high-quality glutinous rice with good disease resistance and adaptability to harsh climates.
Article
Biodiversity Conservation
Zhuo Cheng, Xiaoping Lu, Fengke Lin, Abid Naeem, Chunlin Long
Summary: This study conducted a systematic investigation on the wild edible plants (WEPs) used by the Dulong people in China. The results showed that the Dulong people consume a diverse range of WEPs, some of which have economic potential. Further studies on the nutritional value, chemical composition, and biological activities of these plants are needed.
JOURNAL OF ETHNOBIOLOGY AND ETHNOMEDICINE
(2022)
Article
Green & Sustainable Science & Technology
Mingjing Zhu, Binsheng Luo, Ben La, Ruijie Chen, Fenggui Liu, Chunlin Long
Summary: Salar people in China are a Turkic-speaking ethnic group who are facing the extinction of their traditional wattled-wall house. A study was conducted to support cultural preservation efforts, including documenting traditional knowledge and evaluating the current status of the wattled-wall house. The study found that the knowledge is still passed down from generation to generation, but practical reasons have put the construction at risk.
Article
Plant Sciences
Peter J. Matthews, Van Du Nguyen, Qiong Fang, Chun-Lin Long
Summary: Colocasia spongifolia is a large herb found in forest edges on mountain slopes in southern China and central Vietnam. It is characterized by its distinct vegetative morphology with rubbery and spongy leaf blades, and it reproduces through direct sprouting of lateral buds without producing side-tubers or stolons.
Article
Agronomy
Yingjie Song, Zhuo Cheng, Yumei Dong, Dongmei Liu, Keyu Bai, Devra Jarvis, Jinchao Feng, Chunlin Long
Summary: The assessment of genetic diversity in Tartary buckwheat revealed high levels of diversity within morphological and molecular characteristics. The Tartary buckwheat accessions were divided into three categories, which align with folk nomenclature and taxonomy. The study also found that folk nomenclature, folk taxonomy, and sociocultural norms play a significant role in shaping diversity.
Article
Biology
Yanxiao Fan, Zhuo Cheng, Qing Zhang, Yong Xiong, Bingcong Li, Xiaoping Lu, Liu He, Xia Jiang, Qi Tan, Chunlin Long
Summary: The Bai people in Eryuan, Dali, Yunnan, China have a long history of consuming plums and have developed a meaningful plum-consuming culture. They cultivate plum trees and make various plum products, making the plum industry one of the economic pillars in Eryuan.
Article
Biology
Yanan Chu, Chen Lin, Zhuo Cheng, Xingcen Zhao, Yanxiao Fan, Binsheng Luo, Chunlin Long
Summary: This study investigates the biocultural diversity associated with Gaoligongshan pigs and finds that the local ethnic minorities have accumulated rich biocultural knowledge about these pigs, forming a cultural complex. The study also shows that the semi-wild and free-ranging management model of Gaoligongshan pigs is consistent with the local natural environment, traditional culture, and economic level.
Article
Biochemistry & Molecular Biology
Ruifei Zhang, Zhuo Cheng, Qiong Fang, Edward J. Kennelly, Chunlin Long
Summary: Hypericum species (Hypericaceae) are important plants with medicinal, edible, and ornamental values. A study on H. hengshanense led to the discovery and characterization of 25 monoterpenoid acylphloroglucinols (MAPs), including 10 undescribed compounds. The structures were determined using UV, HR-ESI-MS, and NMR, while the absolute configurations were determined through ECD analysis. Furthermore, several compounds exhibited broad-spectrum antiproliferative activities against various human cell lines.
Article
Plant Sciences
Zhuo Cheng, Xiaoping Lu, Xian Hu, Qing Zhang, Maroof Ali, Chunlin Long
Summary: The greatest global challenge is ensuring access to adequate and nutritious food for all. Wild edible plants, particularly those that serve as substitutes for staple foods, can enhance food security and provide a balanced diet in rural communities. This study investigated the traditional knowledge of Caryota obtusa, a staple food plant substitute for the Dulong people in Northwest Yunnan, China, and evaluated its chemical composition, properties, and distribution. The results showed that C. obtusa is a significant starch species with cultural significance and has a potential geographical distribution in southern China, northern Myanmar, southwestern India, and eastern Vietnam. Cultivating and processing C. obtusa could contribute to local food security and economic benefit, addressing long-term and hidden hunger in rural areas.
Article
Agriculture, Multidisciplinary
Fengke Lin, Edward J. Kennelly, Roger G. Linington, Chunlin Long
Summary: This study conducted a comprehensive metabolomic and bioactivity evaluation of different plant parts from Garcinia yunnanensis and Garcinia xanthochymus. Differences in metabolite profiles and bioactivity were observed among different plant parts. The seeds and latex of both species exhibited excellent cytotoxic and antibacterial activities, while the roots of G. xanthochymus and the arils of G. yunnanensis showed strong anti-inflammatory effects.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Denia Cai Shi, Chunlin Long, Ella Vardeman, Edward J. Kennelly, Michael A. Lawton, Rong Di
Summary: Vitamin B12 deficiency can cause oxidative stress, which is linked to neurodegenerative diseases such as Alzheimer's disease. Mogrosides, derived from plants, have anti-inflammatory and antioxidant activity. This study found that mogrosides can improve the lifespan and egg-laying rate of worms with vitamin B12 deficiency. Additionally, mogrosides delay paralysis in worms expressing amyloid-beta peptide. The protective effects of mogrosides may be due to their ability to modulate oxidative protective gene expression.
Article
Plant Sciences
Fengke Lin, Binsheng Luo, Zhuo Cheng, Ping Li, Chunlin Long
Summary: The genus Garcinia L. (Clusiaceae) has significant ethnobotanical and pharmacological importance globally, particularly in China where it has been used for various purposes including traditional medicine and food. Despite this long history of use, comprehensive ethnobotanical studies are limited. Chinese people have gained traditional knowledge regarding Garcinia plants, including their use in various aspects such as food, medicine, ornamental trees, construction, and culture. However, concerns arising from socio-economic changes have been identified, and strategies are needed for conservation of both traditional botanical knowledge and plants.
ACTA SOCIETATIS BOTANICORUM POLONIAE
(2021)
Article
Plant Sciences
Yi Zhu, Junlin Wang, Lu Tang, Yuxin Shang, Weiyi Zhao, Wei Zhang, Ping Hai, Yongbiao Zheng, Wenbo Li, Yanfang Su
Summary: One new iridoid glucoside and two new lignan glycosides, along with three known compounds, were isolated from the whole plants of Lancea tibetica. The structures were determined by spectroscopic methods and X-ray crystallographic analysis. One of the new iridoid glucosides and the known compounds exhibited moderate antioxidant activity.
PHYTOCHEMISTRY LETTERS
(2024)
Article
Plant Sciences
Yi Deng, Minghua Chen, Junming Yi, Yuguo Zheng
Summary: This study successfully designed and synthesized a series of quinazolinone derivatives containing purine molecules, and found that some compounds exhibited strong antiviral activity against tobacco mosaic virus. The findings have important implications for further development of antiviral drugs.
PHYTOCHEMISTRY LETTERS
(2024)
