4.7 Article

Phomoeuphorbins A-D, azaphilones from the fungus Phomopsis euphorbiae

期刊

PHYTOCHEMISTRY
卷 69, 期 13, 页码 2523-2526

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2008.07.013

关键词

Phomopsis euphorbiae; Trewia nudiflora; Euphorbiaceae; Azaphilone; Phomoeuphorbin; Anti-HIV

资金

  1. National Natural Science Foundation of China [30400038]
  2. Key Scientific and Technological Projects of Yunnan province [2004NG12]
  3. Chinese Academy of Sciences

向作者/读者索取更多资源

Four azaphilones, named phomoeuphorbins A-D (1-4) were isolated from cultures of Phomopsis euphorbiae, an endophytic fungus isolated from Trewia nudiflora. Structures of 1-4 were established on the basis of spectroscopic analyses, including application of 2D NMR spectroscopic techniques. Phomoeuphorbins A and C exhibited very weak inhibitory activities against HIV replication in C8166 cells in vitro. (c) 2008 Elsevier Ltd. All rights reserved.

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