期刊
PHYSIOLOGY
卷 29, 期 2, 页码 122-132出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00045.2013
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类别
资金
- National Heart, Lung, and Blood Institute [HL-074927, HL-51971]
- American Heart Association [12POST11980021]
- Norman Siegel Research Scholar Grant for the American Society of Nephrology (ASN)
The Developmental Origins of Health and Disease (DOHaD) proposes that adverse events during early life program an increased risk for cardiovascular disease. Experimental models provide proof of concept but also indicate that insults during early life program sex differences in adult blood pressure and cardiovascular risk. This review will highlight the potential mechanisms that contribute to the etiology of sex differences in the developmental programming of cardiovascular disease.
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