期刊
PHYSIOLOGY
卷 25, 期 6, 页码 357-363出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00030.2010
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Ca+-dependent Cl- channels (CaCCs) play a variety of physiological roles in different organs and tissues, including transepithelial Cl- secretion, smooth muscle contraction, regulation of neuronal excitability, and transduction of sensory stimuli. The recent identification of TMEM16A protein as an important component of CaCCs should allow a better understanding of their physiological role, structure-function relationship, and regulatory mechanisms.
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