Selenoproteins: Molecular Pathways and Physiological Roles

Selenocysteine Confers Resistance to Inactivation by Oxidation in Thioredoxin Reductase: Comparison of Selenium and Sulfur Enzymes

(2013) Gregg W. Snider et al.   BIOCHEMISTRY

Contribution of Selenocysteine to the Peroxidase Activity of Selenoprotein S

(2013) Jun Liu et al.   BIOCHEMISTRY

The Intrinsically Disordered Membrane Protein Selenoprotein S Is a Reductase in Vitro

(2013) Jun Liu et al.   BIOCHEMISTRY

Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W

(2013) Yeong Ha Jeon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Disruption of Thioredoxin Reductase 1 Protects Mice from Acute Acetaminophen-Induced Hepatotoxicity through Enhanced NRF2 Activity

(2013) Andrew D. Patterson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The PACAP-Regulated Gene Selenoprotein T Is Abundantly Expressed in Mouse and Human β-Cells and Its Targeted Inactivation Impairs Glucose Tolerance

(2013) Gaëtan Prevost et al.   ENDOCRINOLOGY

Maternal-fetal transfer of selenium in the mouse

(2013) Raymond F. Burk et al.   FASEB JOURNAL

Stereospecific oxidation of calmodulin by methionine sulfoxide reductase A

(2013) Jung Chae Lim et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification

(2013) Sonya V. Iverson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selenium and diabetes—Evidence from animal studies

(2013) Jun Zhou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Different Forms of Selenoprotein M Differentially Affect Aβ Aggregation and ROS Generation

(2013) Ping Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The central role of selenium in the biochemistry and ecology of the harmful pelagophyte, Aureococcus anophagefferens

(2013) Christopher J Gobler et al.   ISME Journal

Deletion of Selenoprotein M Leads to Obesity without Cognitive Deficits

(2013) Matthew W. Pitts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High Error Rates in Selenocysteine Insertion in Mammalian Cells Treated with the Antibiotic Doxycycline, Chloramphenicol, or Geneticin

(2013) Ryuta Tobe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Long D-stem of the Selenocysteine tRNA Provides Resilience at the Expense of Maximal Function

(2013) Tetsu M. Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Translational Redefinition of UGA Codons Is Regulated by Selenium Availability

(2013) Michael T. Howard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reconstitution of Selenocysteine Incorporation Reveals Intrinsic Regulation by SECIS Elements

(2013) Nirupama Gupta et al.   JOURNAL OF MOLECULAR BIOLOGY

MsrB1 and MICALs Regulate Actin Assembly and Macrophage Function via Reversible Stereoselective Methionine Oxidation

(2013) Byung Cheon Lee et al.   MOLECULAR CELL

UGA codon position-dependent incorporation of selenocysteine into mammalian selenoproteins

(2013) A. A. Turanov et al.   NUCLEIC ACIDS RESEARCH

Tertiary structure of bacterial selenocysteine tRNA

(2013) Y. Itoh et al.   NUCLEIC ACIDS RESEARCH

SECISearch3 and Seblastian: new tools for prediction of SECIS elements and selenoproteins

(2013) Marco Mariotti et al.   NUCLEIC ACIDS RESEARCH

Methionine oxidation activates a transcription factor in response to oxidative stress

(2013) Adrian Drazic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-  receptor tyrosine kinase signaling

(2013) M. Dagnell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decameric SelAbullettRNASec Ring Structure Reveals Mechanism of Bacterial Selenocysteine Formation

(2013) Y. Itoh et al.   SCIENCE

Role of Reactive Oxygen Species-Mediated Signaling in Aging

(2012) Vyacheslav M. Labunskyy et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenoprotein W promotes cell cycle recovery from G2 arrest through the activation of CDC25B

(2012) Yong Hwan Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis

(2012) Bradley A. Carlson et al.   CARCINOGENESIS

Post-translational modification and regulation of actin

(2012) Jonathan R Terman et al.   CURRENT OPINION IN CELL BIOLOGY

A high-selenium diet induces insulin resistance in gestating rats and their offspring

(2012) Min-Shu Zeng et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Human Selenoprotein VCP-interacting Membrane Protein (VIMP) Is Non-globular and Harbors a Reductase Function in an Intrinsically Disordered Region

(2012) Lea Cecilie Christensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into Interaction between Mammalian Methionine Sulfoxide Reductase B1 and Thioredoxin

(2012) Olena Dobrovolska et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Supranutritional selenium induces alterations in molecular targets related to energy metabolism in skeletal muscle and visceral adipose tissue of pigs

(2012) Antonio Pinto et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Selenium and human health

(2012) Margaret P Rayman   LANCET

Disruption of the Selenocysteine Lyase-Mediated Selenium Recycling Pathway Leads to Metabolic Syndrome in Mice

(2012) L. A. Seale et al.   MOLECULAR AND CELLULAR BIOLOGY

A Novel Protein Kinase-Like Domain in a Selenoprotein, Widespread in the Tree of Life

(2012) Małgorzata Dudkiewicz et al.   PLoS One

Composition and Evolution of the Vertebrate and Mammalian Selenoproteomes

(2012) Marco Mariotti et al.   PLoS One

Biochemical Discrimination between Selenium and Sulfur 1: A Single Residue Provides Selenium Specificity to Human Selenocysteine Lyase

(2012) Ruairi Collins et al.   PLoS One

Selenocysteine Insertion Sequence Binding Protein 2L Is Implicated as a Novel Post-Transcriptional Regulator of Selenoprotein Expression

(2012) Jesse Donovan et al.   PLoS One

Knockout of the 15 kDa Selenoprotein Protects against Chemically-Induced Aberrant Crypt Formation in Mice

(2012) Petra A. Tsuji et al.   PLoS One

Selenium Regulation of the Selenoprotein and Nonselenoprotein Transcriptomes in Rodents

(2012) Roger A. Sunde et al.   Advances in Nutrition

Both Maximal Expression of Selenoproteins and Selenoprotein Deficiency Can Promote Development of Type 2 Diabetes-Like Phenotype in Mice

(2011) Vyacheslav M. Labunskyy et al.   ANTIOXIDANTS & REDOX SIGNALING

Comparative Genomics of Thiol Oxidoreductases Reveals Widespread and Essential Functions of Thiol-based Redox Control of Cellular Processes

(2011) Dmitri E. Fomenko et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of selenocysteine tRNA[Ser]Sec aminoacylation provides evidence that aminoacylation is required for regulatory methylation of this tRNA

(2011) Jin Young Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Drosophila selenophosphate synthetase 1 regulates vitamin B6 metabolism: prediction and confirmation

(2011) Kwang Hee Lee et al.   BMC GENOMICS

Enhancement of Carboplatin-Mediated Lung Cancer Cell Killing by Simultaneous Disruption of Glutathione and Thioredoxin Metabolism

(2011) M. A. Fath et al.   CLINICAL CANCER RESEARCH

Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress

(2011) Peter M. Scarbrough et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gorilla genome structural variation reveals evolutionary parallelisms with chimpanzee

(2011) M. Ventura et al.   GENOME RESEARCH

Reduced Utilization of Selenium by Naked Mole Rats Due to a Specific Defect in GPx1 Expression

(2011) Marina V. Kasaikina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of the 15-kDa Selenoprotein (Sep15) in Redox Homeostasis and Cataract Development Revealed by the Analysis of Sep 15 Knockout Mice

(2011) Marina V. Kasaikina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenoprotein K Binds Multiprotein Complexes and Is Involved in the Regulation of Endoplasmic Reticulum Homeostasis

(2011) Valentina A. Shchedrina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenoprotein K Knockout Mice Exhibit Deficient Calcium Flux in Immune Cells and Impaired Immune Responses

(2011) S. Verma et al.   JOURNAL OF IMMUNOLOGY

Selenium Levels Affect the IL-4–Induced Expression of Alternative Activation Markers in Murine Macrophages

(2011) Shakira M. Nelson et al.   JOURNAL OF NUTRITION

Mammalian Selenocysteine Lyase Is Involved in Selenoprotein Biosynthesis

(2011) Suguru KUROKAWA et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Increased Muscle Stress-Sensitivity Induced by Selenoprotein N Inactivation in Mouse: A Mammalian Model for SEPN1-Related Myopathy

(2011) Mathieu Rederstorff et al.   PLoS One

Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide

(2011) D. E. Fomenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Redox Regulation of F-Actin Assembly and Disassembly by Mical

(2011) R.-J. Hung et al.   SCIENCE

Mutations Disrupting Selenocysteine Formation Cause Progressive Cerebello-Cerebral Atrophy

(2010) Orly Agamy et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Impacts of Dietary Selenium Deficiency on Metabolic Phenotypes of Diet-Restricted GPX1-Overexpressing Mice

(2010) Matthew P. Pepper et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

(2010) Edith Lubos et al.   ANTIOXIDANTS & REDOX SIGNALING

Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain

(2010) Jazmin Chiu-Ugalde et al.   BIOCHEMICAL JOURNAL

Methaneseleninic Acid Is a Substrate for Truncated Mammalian Thioredoxin Reductase: Implications for the Catalytic Mechanism and Redox Signaling

(2010) Gregg Snider et al.   BIOCHEMISTRY

Deficiency in the 15-kDa Selenoprotein Inhibits Tumorigenicity and Metastasis of Colon Cancer Cells

(2010) R. Irons et al.   Cancer Prevention Research

Loss of Thioredoxin Reductase 1 Renders Tumors Highly Susceptible to Pharmacologic Glutathione Deprivation

(2010) P. K. Mandal et al.   CANCER RESEARCH

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

(2010) Hirofumi Misu et al.   Cell Metabolism

Selenoproteins—What unique properties can arise with selenocysteine in place of cysteine?

(2010) Elias S.J. Arnér   EXPERIMENTAL CELL RESEARCH

Polymorphisms in the selenoprotein S and 15-kDa selenoprotein genes are associated with altered susceptibility to colorectal cancer

(2010) Alison Sutherland et al.   Genes and Nutrition

Satellite cell loss and impaired muscle regeneration in selenoprotein N deficiency

(2010) Perrine Castets et al.   HUMAN MOLECULAR GENETICS

Insights into Function, Catalytic Mechanism, and Fold Evolution of Selenoprotein Methionine Sulfoxide Reductase B1 through Structural Analysis

(2010) Finn L. Aachmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methionine Sulfoxide Reductase B1 (MsrB1) Recovers TRPM6 Channel Activity during Oxidative Stress

(2010) Gang Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reaction Mechanism and Molecular Basis for Selenium/Sulfur Discrimination of Selenocysteine Lyase

(2010) Rie Omi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenoprotein-Related Disease in a Young Girl Caused by Nonsense Mutations in theSBP2Gene

(2010) Monalisa Ferreira Azevedo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mutations in the selenocysteine insertion sequence–binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

(2010) Erik Schoenmakers et al.   JOURNAL OF CLINICAL INVESTIGATION

The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration

(2010) Monica Dentice et al.   JOURNAL OF CLINICAL INVESTIGATION

Interaction of Selenoprotein W with 14-3-3 Proteins: A Computational Approach

(2010) Francesco Musiani et al.   JOURNAL OF PROTEOME RESEARCH

Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine

(2010) Shiho Chiba et al.   MOLECULAR CELL

Mical links semaphorins to F-actin disassembly

(2010) Ruei-Jiun Hung et al.   NATURE

C-terminal domain of archaeal O -phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNA Sec

(2010) R. Lynn Sherrer et al.   NUCLEIC ACIDS RESEARCH

Nucleolin binds to a subset of selenoprotein mRNAs and regulates their expression

(2010) Angela C. Miniard et al.   NUCLEIC ACIDS RESEARCH

Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery

(2010) X.-M. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

(2010) M. Conrad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress inSEPN1-related myopathy: From pathophysiology to treatment

(2009) Sandrine Arbogast et al.   ANNALS OF NEUROLOGY

Regulation of Selenoproteins and Methionine Sulfoxide Reductases A and B1 by Age, Calorie Restriction, and Dietary Selenium in Mice

(2009) Sergey V. Novoselov et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenoproteins and Protection against Oxidative Stress: Selenoprotein N as a Novel Player at the Crossroads of Redox Signaling and Calcium Homeostasis

(2009) Sandrine Arbogast et al.   ANTIOXIDANTS & REDOX SIGNALING

The Neuroprotective Functions of Selenoprotein M and its Role in Cytosolic Calcium Regulation

(2009) Mariclair A. Reeves et al.   ANTIOXIDANTS & REDOX SIGNALING

Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer's Disease

(2009) Min-Hyuk Yoo et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenium and the Selenoprotein Thioredoxin Reductase in the Prevention, Treatment and Diagnostics of Cancer

(2009) Markus Selenius et al.   ANTIOXIDANTS & REDOX SIGNALING

Sep15, a Thioredoxin-like Selenoprotein, Is Involved in the Unfolded Protein Response and Differentially Regulated by Adaptive and Acute ER Stresses

(2009) Vyacheslav M. Labunskyy et al.   BIOCHEMISTRY

Selenoprotein T deficiency alters cell adhesion and elevates selenoprotein W expression in murine fibroblast cells

(2009) Aniruddha Sengupta et al.   Biochemistry and Cell Biology

Selenoproteins that function in cancer prevention and promotion

(2009) Dolph L. Hatfield et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Functions and evolution of selenoprotein methionine sulfoxide reductases

(2009) Byung Cheon Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium

(2009) Lutz Schomburg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The labour pains of biochemical selenology: The history of selenoprotein biosynthesis

(2009) Leopold Flohé   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Identification of Proteins Interacting with Selenocysteine Lyase

(2009) Ryuta TOBE et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Evolutionary history of selenocysteine incorporation from the perspective of SECIS binding proteins

(2009) Jesse Donovan et al.   BMC EVOLUTIONARY BIOLOGY

Selenoprotein S (SEPS1) gene -105G>A promoter polymorphism influences the susceptibility to gastric cancer in the Japanese population

(2009) Tomoyuki Shibata et al.   BMC GASTROENTEROLOGY

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Comparative Genomics of Trace Elements: Emerging Dynamic View of Trace Element Utilization and Function

(2009) Yan Zhang et al.   CHEMICAL REVIEWS

Mitochondrial glutathione peroxidase 4 disruption causes male infertility

(2009) Manuela Schneider et al.   FASEB JOURNAL

Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver

(2009) Jun Lu et al.   FASEB JOURNAL

Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration

(2009) Eva K. Wirth et al.   FASEB JOURNAL

CUG Start Codon Generates Thioredoxin/Glutathione Reductase Isoforms in Mouse Testes

(2009) Maxim V. Gerashchenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Short Form Glutathione Peroxidase 4 Is the Essential Isoform Required for Survival and Somatic Mitochondrial Functions

(2009) Hanyu Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevation of Glutamine Level by Selenophosphate Synthetase 1 Knockdown Induces Megamitochondrial Formation in Drosophila Cells

(2009) Myoung Sup Shim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

General Trends in Trace Element Utilization Revealed by Comparative Genomic Analyses of Co, Cu, Mo, Ni, and Se

(2009) Yan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutathione Peroxidase-1 Regulates Mitochondrial Function to Modulate Redox-dependent Cellular Responses

(2009) Diane E. Handy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proximity-based Protein Thiol Oxidation by H2O2-scavenging Peroxidases

(2009) Marcus Gutscher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical and Molecular Characterization of a Novel Selenocysteine Insertion Sequence-Binding Protein 2 (SBP2) Gene Mutation (R128X)

(2009) Caterina Di Cosmo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Low Exchangeability of Selenocysteine, the 21st Amino Acid, in Vertebrate Proteins

(2009) S. Castellano et al.   MOLECULAR BIOLOGY AND EVOLUTION

Eukaryotic Initiation Factor 4a3 Is a Selenium-Regulated RNA-Binding Protein that Selectively Inhibits Selenocysteine Incorporation

(2009) Michael E. Budiman et al.   MOLECULAR CELL

Structural and kinetic analysis of an MsrA-MsrB fusion protein fromStreptococcus pneumoniae

(2009) Young Kwan Kim et al.   MOLECULAR MICROBIOLOGY

Crystal structure of human selenocysteine tRNA

(2009) Yuzuru Itoh et al.   NUCLEIC ACIDS RESEARCH

A short motif in Drosophila SECIS Binding Protein 2 provides differential binding affinity to SECIS RNA hairpins

(2009) Akiko Takeuchi et al.   NUCLEIC ACIDS RESEARCH

Novel structural determinants in human SECIS elements modulate the translational recoding of UGA as selenocysteine

(2009) Lynda Latrèche et al.   NUCLEIC ACIDS RESEARCH

Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon

(2009) A. A. Turanov et al.   SCIENCE

The Human SepSecS-tRNASec Complex Reveals the Mechanism of Selenocysteine Formation

(2009) S. Palioura et al.   SCIENCE

Genetic association of preeclampsia to the inflammatory response gene SEPS1

(2008) Eric K. Moses et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The Catalytic Site of Glutathione Peroxidases

(2008) Silvio C. E. Tosatto et al.   ANTIOXIDANTS & REDOX SIGNALING

Evolutionary and Structural Insights Into the Multifaceted Glutathione Peroxidase (Gpx) Superfamily

(2008) Stefano Toppo et al.   ANTIOXIDANTS & REDOX SIGNALING

Thioredoxin as a reducing agent for mammalian methionine sulfoxide reductases B lacking resolving cysteine

(2008) Hwa-Young Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination inSepp-knockout mice

(2008) Kostja Renko et al.   BIOCHEMICAL JOURNAL

Selenium in Thioredoxin Reductase: A Mechanistic Perspective†

(2008) Brian M. Lacey et al.   BIOCHEMISTRY

Selenium status highly regulates selenoprotein mRNA levels for only a subset of the selenoproteins in the selenoproteome

(2008) Roger A. Sunde et al.   BIOSCIENCE REPORTS

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation

(2008) Jeffrey R. Erickson et al.   CELL

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism

Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice

(2008) X. D. Wang et al.   DIABETOLOGIA

Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling1

(2008) Balázs Gereben et al.   ENDOCRINE REVIEWS

Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion

(2008) Luca Grumolato et al.   FASEB JOURNAL

Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers

(2008) Scott M. Lippman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mammals Reduce Methionine-S-sulfoxide with MsrA and Are Unable to Reduce Methionine-R-sulfoxide, and This Function Can Be Restored with a Yeast Reductase

(2008) Byung Cheon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Protein Domain Induces High Affinity Selenocysteine Insertion Sequence Binding and Elongation Factor Recruitment

(2008) Jesse Donovan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin Reductase-1 Negatively Regulates HIV-1 Transactivating Protein Tat-dependent Transcription in Human Macrophages

(2008) Parisa Kalantari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure and Catalysis of the Selenoprotein Thioredoxin Reductase 1

(2008) Qing Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MsrB1(Methionine-R-sulfoxide Reductase 1) Knock-out Mice

(2008) Dmitri E. Fomenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Megalin Mediates Selenoprotein P Uptake by Kidney Proximal Tubule Epithelial Cells

(2008) Gary E. Olson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Analysis of Free Methionine-R-sulfoxide Reductase fromSaccharomyces cerevisiae

(2008) Dung Tien Le et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle

(2008) M. J. Jurynec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The selenoproteome ofClostridiumsp. OhILAs: Characterization of anaerobic bacterial selenoprotein methionine sulfoxide reductase A

(2008) Hwa-Young Kim et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Reduced reliance on the trace element selenium during evolution of mammals

(2008) Alexey V Lobanov et al.   GENOME BIOLOGY