Review
Agriculture, Dairy & Animal Science
Eleni Dovolou, Themistoklis Giannoulis, Ioannis Nanas, Georgios S. Amiridis
Summary: Global warming poses a significant threat to the dairy sector, affecting both tropical and temperate regions. High temperatures compromise the welfare and fertility of dairy cows, leading to economic losses for farmers. Dairy cows employ various adaptive mechanisms to cope with heat stress, but the disruption of hormone secretion has long-lasting effects on fertility. Mitigation measures can restore milk production, but summer fertility records remain low due to the multifaceted nature of sustaining high fertility and proper reproductive processes.
Review
Agriculture, Dairy & Animal Science
M. L. Rhoads
Summary: Heat stress has severe consequences for agricultural production, and its impact is exacerbated by global warming. Climate change is predicted to lead to reproductive problems, decreased milk production, and overall productivity losses. Development of technologies and management strategies to improve animal production capacity and efficiency during heat stress is urgently needed.
Article
Agriculture, Dairy & Animal Science
P. Maentysaari, J. Juga, M. H. Lidauer, J. Haeggman, T. Mehtioe, J. M. Christensen, E. A. Maentysaari
Summary: This study aimed to investigate the relationships between energy status indicators and fertility traits in dairy cows during different stages of lactation. The findings showed a higher correlation between energy status and fertility traits, especially in multiparous cows.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Reproductive Biology
Ali Husnain, Usman Arshad, Roney Zimpel, Eduardo Schmitt, Mackenzie J. Dickson, Milerky C. Perdomo, Mariana N. Marinho, Nadia Ashrafi, Stewart F. Graham, Jeanette Bishop, Thomas R. Hansen, Kwang C. Jeong, Angela M. Gonella-Diaza, Ricardo C. Chebel, I. Martin Sheldon, John J. Bromfield, Jose E. P. Santos
Summary: Endometrial inflammation in cows is associated with reduced pregnancy rates and increased pregnancy loss. Induced endometritis alters histotroph composition and induces inflammatory signatures on conceptus, compromising their development. Bacterial-induced endometritis impairs conceptus development by altering histotroph composition and conceptus gene expression in dairy cattle.
BIOLOGY OF REPRODUCTION
(2023)
Article
Agriculture, Dairy & Animal Science
J. J. Gross, R. Sturmlin, R. M. Bruckmaier
Summary: Short-term imbalances in dietary nutrients can affect metabolic and endocrine responses in dairy cows, which are crucial for precise feeding strategies.
Article
Cell Biology
E. O'Callaghan, J. M. Sanchez, M. B. Rabaglino, M. McDonald, H. Liu, T. E. Spencer, S. Fair, D. A. Kenny, P. Lonergan
Summary: The study found that conceptuses with high fertility status can stimulate multiple pathways involved in immune response, similar to IFNT treatment, while conceptuses with low fertility status apparently have no effect on these pathways.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Veterinary Sciences
Robert Mikula, Ewa Pruszynska-Oszmalek, Marcin Pszczola, Justyna Rzasinska, Maciej Sassek, Krzysztof W. Nowak, Leszek Nogowski, Pawel A. Kolodziejski
Summary: The study found that the concentration of spexin in dairy cows during the transition period from 21 days before parturition to 21 days postpartum showed a certain trend of change, being negatively correlated with NEFA, BHBA, and total ghrelin, and positively correlated with progesterone concentration. Additionally, mRNA expression of the spexin gene was detected in various bovine tissues.
BMC VETERINARY RESEARCH
(2021)
Article
Agriculture, Dairy & Animal Science
M. Spanghero, Z. M. Kowalski
Summary: Nitrogen balance experiments with lactating dairy cows tend to overestimate nitrogen retention, with losses of nitrogen from feces and urine being the most likely reason.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
R. S. Bisinotto, E. S. Ribeiro, L. F. Greco, D. Taylor-Rodriguez, A. D. Ealy, H. Ayres, F. S. Lima, N. Martinez, W. W. Thatcher, J. E. P. Santos
Summary: This study evaluated the effects of follicular wave and progesterone concentration on growth of the ovulatory follicle, conceptus elongation, uterine IFN-tau concentration, and transcriptome of conceptus and endometrium in pregnant cows. The results indicated that progesterone concentration had an impact on the growth of ovulatory follicle, but overall had minimal effects on the conceptus and endometrium transcriptome.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agricultural Engineering
Jinghui Li, Vinod Narayanan, Ermias Kebreab, Serdal Dikmen, James G. Fadel
Summary: A dynamic model was developed to predict the thermal balance of Holstein dairy cattle, showing sensitivity to heat production, surface area, respiration, and sweating parameters. The model accurately simulated body temperatures under typical summer conditions in California, providing insights for the use of cooling strategies in dairy facilities.
BIOSYSTEMS ENGINEERING
(2021)
Article
Biochemical Research Methods
Turner H. Swartz, Uzi Moallem, Hadar Kamer, Gitit Kra, Yishai Levin, Laman K. Mamedova, Barry J. Bradford, Maya Zachut
Summary: Negative energy balance in early lactation dairy cows is associated with metabolic disorders, leading to altered liver proteome characterized by shifts in hepatic protein abundance involved in fatty acid uptake, impaired anti-inflammatory responses, and mitochondrial dysfunction. Differentially abundant proteins identified in this study may serve as potential biological markers for disease or targets for improving metabolic adaptations in postpartum dairy cattle.
JOURNAL OF PROTEOMICS
(2021)
Article
Agriculture, Dairy & Animal Science
V. A. E. Becker, E. Stamer, G. Thaller
Summary: Efficiency of dairy cows is largely influenced by dry matter intake (DMI). Decreasing DMI may increase efficiency, but can also lead to negative energy balance and health issues, especially in early lactation. Multiparous cows are more likely to be susceptible to diseases compared to primiparous cows, with higher incidences of claw and leg diseases, followed by metabolic diseases and mastitis.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Reproductive Biology
C. B. Reed, S. Meier, L. A. Murray, C. R. Burke, J. L. Pitman
Summary: Our study compared the follicular microenvironment of heifers and cows with positive genetic merit for fertility, finding that cows with high genetic merit have higher quality cumulus cell-oocyte complexes and oocytes. Lower fertility value heifers had inconsistent sampling times, lower COC maturity, and differential gene expression associated with follicular maturation.
Article
Agriculture, Dairy & Animal Science
A. Guinguina, T. Yan, E. Trevisi, P. Huhtanen
Summary: Measurements of energy balance require the use of respiration chambers, but the GreenFeed system offers a less expensive alternative. This study used the GreenFeed system to estimate energy balance in early-lactating dairy cows and found good concordance with predicted energy balance from Finnish feeding standards. Further validation of the GreenFeed system is needed for a wider range of dietary conditions.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Veterinary Sciences
M. Tekin, D. R. Camara, T. M. Binz, R. M. Bruckmaier, H. Bollwein, K. Wagener
Summary: This study examined the dynamics of hair cortisol concentration (HCC) in diseased and healthy dairy cows from eight-week ante partum (AP) to eight-week post partum (PP). The results showed that HCC was not associated with peripartum diseases, but was correlated with body condition score loss, heat stress, and breed.
RESEARCH IN VETERINARY SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Fulin Liu, Christelle Simasotchi, Francoise Vibert, Wencan Zhu, Sophie Gil, Severine A. Degrelle, Thierry Fournier
Summary: This study investigated changes in gene expression in the placenta due to the rise in physiological oxygen tension, utilizing RNA sequencing to identify key genes and analyze enrichment patterns. The results provide insights into potential drug-targeted genes or pathways in the human placenta.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Infectious Diseases
Maellys Kevin, Guillaume Girault, Yvan Caspar, Moulay Ali Cherfa, Christiane Mendy, Max Maurin, Claire Ponsart, Nora Madani
Summary: Tularemia in Europe is predominantly caused by Francisella tularensis subsp. holarctica, affecting wildlife animals and humans sporadically. The classification of this species depends on canonical single nucleotide polymorphisms (canSNPs), with four main clades identified. Phylogeographic studies have shown that clade B.6 is predominant in Western Europe, while B.12 is predominant in Eastern and Central Europe. High-resolution melting (HRM) primers were designed for screening 109 canSNPs to analyze molecular epidemiology and track F. tularensis subsp. holarctica in Western Europe.
INFECTION GENETICS AND EVOLUTION
(2021)
Article
Veterinary Sciences
Viviane Henaux, Claire Ponsart, Justine Corre, Florence Etore, Henri-Jean Boulouis, Herve Morvan, Lionel Grisot, Carole Peroz
Summary: The study evaluated the effectiveness of bTB surveillance in high-risk areas in France, finding that increasing monitoring and preventive measures can significantly improve the detection fraction of infected herds.
PREVENTIVE VETERINARY MEDICINE
(2021)
Article
Microbiology
Luca Freddi, Vitomir Djokic, Fathia Petot-Bottin, Guillaume Girault, Ludivine Perrot, Acacia Ferreira Vicente, Claire Ponsart
Summary: Brucellosis is a worldwide zoonosis caused by bacteria from the genus Brucella. This study compared different swab types for sampling and diagnostics, and determined the optimal storage conditions and time frame for testing. Despite storage conditions, flocked swabs showed the highest capacity to preserve bacterial viability and DNA quality.
MICROBIOLOGY SPECTRUM
(2021)
Article
Microbiology
Guillaume Girault, Ludivine Perrot, Virginie Mick, Claire Ponsart
Summary: In this study, a high-resolution melting (HRM) method was developed for the rapid identification and classification of the Brucella genus based on 17 specific single nucleotide polymorphisms (SNPs) and SNP analysis. This genotyping tool provides a new and quick alternative for Brucella identification, significantly saving time for the diagnosis of brucellosis.
Article
Biology
Fulin Liu, Christine Rouault, Karine Clement, Wencan Zhu, Severine A. Degrelle, Marie-Aline Charles, Barbara Heude, Thierry Fournier
Summary: The study revealed a significant association between the C1431T variant of PPARγ and preeclampsia, while seven features including SNP variants, obesity, and smoking were identified as potential predictors of preeclampsia. Machine-learning algorithms, particularly the boost tree-based model, showed excellent predictive performance for preeclampsia, with high accuracy and AUC values in both training and testing sets.
Article
Environmental Sciences
Severine A. Degrelle, Ioana Ferecatu, Thierry Fournier
Summary: Aryl hydrocarbon receptor (AHR) is a crucial transcription factor involved in various biological processes. Two new reporter genes have been constructed to improve the study of AHR activity, and their capability to monitor AHR activity in different cell types has been demonstrated.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Gaelle Deval, Margaux Nedder, Severine Degrelle, Jasmina Rogozarski, Marie-Leone Vignaud, Audrey Chissey, Stacy Colzin, Christelle Laguillier-Morizot, Xavier Coumoul, Sonja Boland, Thierry Fournier, Amal Zerrad-Saadi, Ioana Ferecatu
Summary: Studying the impact of pollutants on the human placenta is crucial as they can accumulate in placental cells or pass into the fetal circulation. This study aimed to identify the signaling pathways modulated after exposure to benzo(a)pyrene (BaP) and cerium dioxide nanoparticles (CeO2 NP) individually or in combination. BaP, when bioactivated by xenobiotic metabolizing enzymes, leads to DNA damage and stress response in the placental cells. CeO2 NP, on the other hand, has an antioxidant effect. Co-exposure to these two pollutants modulates the genotoxic effect of BaP and reduces oxidative stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Endocrinology & Metabolism
Isabelle Hue, Encarnacion Capilla, Enrique Rosell-Moll, Sara Balbuena-Pecino, Valentine Goffette, Jean-Charles Gabillard, Isabel Navarro
Summary: Control of tissue metabolism and growth involves interactions between organs, tissues, and cell types, mediated by cytokines or direct communication through cellular exchanges. Many peptides produced by adipose tissue, skeletal muscle and bone have been identified in mammals playing key roles in organ/tissue development and function. Some of them have been identified in fish models, and this review summarizes their characteristics and interactions with different tissues.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Microbiology
Guillaume Girault, Vitomir Djokic, Fathia Petot-Bottin, Ludivine Perrot, Bourgoin Thibaut, Hoffmann Sebastien, Acacia Ferreira Vicente, Claire Ponsart, Luca Freddi
Summary: This paper describes the first two cases of Brucella suis biovar 2 (BSB2) infections in French dogs. The cases highlight the importance of adopting a One Health approach to control zoonotic bacteria in wildlife and prevent spillovers into domestic animals and potentially humans.
Article
Multidisciplinary Sciences
Severine A. Degrelle, Julian Buchrieser, Anne Dupressoir, Francoise Porrot, Laurence Loeuillet, Olivier Schwartz, Thierry Fournier
Summary: Interferon-induced transmembrane proteins (IFITMs) are restriction factors that block many viruses from entering cells. High levels of type I interferon (IFN) are associated with adverse pregnancy outcomes, and IFITMs have been shown to impair the formation of syncytiotrophoblast. Here, we examine whether IFITMs affect another critical step of placental development, extravillous cytotrophoblast (EVCT) invasion.
Article
Infectious Diseases
R. L. Vinueza, B. Durand, F. Ortega, F. Salas, A. Ferreira Vicente, L. Freddi, C. Ponsart, G. Zanella
Summary: A cross-sectional study was conducted on bovine brucellosis among 173 medium/small-scale cattle farmers in a tropical region of Ecuador. The study found a prevalence of 11.5% among farms, with higher prevalence in medium farms compared to small farms. The study also identified farm size as a risk factor for the occurrence of reproductive disorders.
TRANSBOUNDARY AND EMERGING DISEASES
(2023)
Meeting Abstract
Developmental Biology
Fulin Liu, Christine Rouault, Karine Clement, Vassilis Tsatsaris, Severine A. Degrelle, Barbara Heude, Thierry Fournier
Meeting Abstract
Developmental Biology
Severine Degrelle, Julian Buchrieser, Francoise Porrot, Olivier Schwartz, Thierry Fournier
Meeting Abstract
Developmental Biology
Camille Gosseaume, Thierry Fournier, Isabelle Jeru, Isabelle Missotte, Catherine Pienkowski, Bruno Guerci, Estelle Nobecourt, Xavier Debussche, Francoise Archambeaud, Jean-Paul Thissen, Olivier Lascols, Severine Degrelle, Corinne Vigouroux, Camille Vatier