期刊
VETERINARY MICROBIOLOGY
卷 175, 期 1, 页码 85-91出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.vetmic.2014.10.014
关键词
Extended spectrum beta lactamases (ESBLs); Plasmid-mediated resistance; Quinolone resistance; IncA/C
资金
- governmental founding of the multi-annual research project Protection of Animal and Human Health at the National Veterinary Research Institute (Ministry of Council Resolution) [244/2008]
Multidrug resistant Salmonella Kentucky strains have been isolated from turkeys in Poland since 2009. Multiple mutations within chromosomal genes gyrA and parC were responsible for high-level ciprofloxacin resistance. One of the isolates was extended spectrum f3-lactamase- (ESBL) positive: the strain 1643/2010 carried a conjugative 167,779 bps plasmid of IncA/C family. The sequence analysis revealed that it carried a blaox_m_25 gene and an integron with another f3-lactamase encoding gene blaoxA_21. This is the first known report of a CTX-M-25 encoding gene both in Poland and in Salmonella Kentucky world-wide, as well as in the IncA/C plasmid. Analysis of the integron showed a novel arrangement of gene cassettes aacA4, aacC-Al and bla0xA_21 where the latter might result from an intergeneric gene transfer. The study confirmed Salmonella Kentucky population isolated in Poland belongs to global epidemics of high level fluoroquinolone resistant clone ST198 that can carry rare 13-lactamase genes. 0 2014 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据