Article
Chemistry, Multidisciplinary
Sebastian P. Schwaminger, David Bauer, Paula Fraga-Garcia
Summary: This study aimed to combine iron oxide nanoparticles with nanoscale gold for improved dye detection. By testing various approaches, the impact of colloidal stability of iron oxide nanoparticles on the properties of the hybrid material was explored. The optimized method showed enhanced Raman scattering capabilities, potentially expanding applications in diagnostics and environmental fields.
NANOSCALE ADVANCES
(2021)
Review
Engineering, Environmental
Qingsong Cheng, Hebing Pei, Qian Ma, Ruibin Guo, Nijuan Liu, Zunli Mo
Summary: This paper reviews the progress of chiral graphene materials for enantiomer separation, discussing their synthesis strategies, separation mechanism, and applications, as well as exploring related issues and future prospects.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Yun Guo, Ling Zhang, Kexuan Wang, Ajuan Yu, Shusheng Zhang, Gangfeng Ouyang
Summary: A rapid approach for the size/morphology-controlled synthesis of CuLBH was developed by adjusting the concentrations of 2-MI and copper ions. The nanosized CuLBH exhibited better selective potential towards NE and provided more fully exposed recognition sites. To further improve the enantioselectivity and avoid aggregation of MOF nanoparticles, the CC-CuLBH composite was designed, showing higher selectivity than pristine CC and nano CuLBH.
CHEMICAL COMMUNICATIONS
(2021)
Article
Engineering, Chemical
Graziano Frungieri, Marco Vanni
Summary: A new method combining Monte Carlo algorithm and Discrete Element Method is proposed for simulating aggregation and breakup processes in colloidal particle suspensions. It accurately reproduces the dynamic steady state observed in liquid-solid suspensions, characterizing the structural properties of aggregates and dynamics of the breakup phenomena in detail.
Article
Chemistry, Multidisciplinary
Naval Singh, Goran T. Vladisavljevic, Francois Nadal, Cecile Cottin-Bizonne, Christophe Pirat, Guido Bolognesi
Summary: The study investigates the effects of salt contrast and groove depth on the accumulation process of colloidal particles in microgrooves, and determines the experimental conditions that lead to high particle concentration peaks. The sufficient and necessary conditions for particle accumulation are derived. The controlled and enhanced accumulation of colloidal particles in dead-end structures by solute concentration gradients has potential applications in soft matter and living systems.
Review
Chemistry, Analytical
Li Zhang, Quan-Gen Tan, Jia-Qi Fan, Chen Sun, Yu-Ting Luo, Ru-Ping Liang, Jian-Ding Qiu
Summary: Microfluidic techniques including CE, CEC, and MEKC have been widely used for the chiral separation of biomolecules. Different strategies are employed in these techniques, such as CS-bonded stationary phase in CEC, addition of CS to the mobile phase in CE, and involvement of chiral surfactants and/or CS in pseudostationary phases of MEKC. Microfluidic techniques offer advantages of high selectivity, excellent separation efficiency, and low cost compared to conventional techniques. This review discusses innovations in detection systems, separation mechanism, CS, and chiral analytes of biomolecules, as well as the most applied CSs and the chiral separation of representative biomolecules. Prospects and future developments of microfluidics for chiral separation are also proposed.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Medicine, Research & Experimental
Akshay Narula, Rayan Sabra, Na Li
Summary: This study investigated the mechanisms and extent of enhanced passive permeation by drug particles using various model drugs. The results showed that flux enhancement by particles depended on particle size and the partitioning behavior of the drug. Mass transport models were used to calculate flux enhancement and good agreements were obtained between experimental and predicted values.
MOLECULAR PHARMACEUTICS
(2022)
Article
Chemistry, Multidisciplinary
Eric N. Donders, Kai V. Slaughter, Christian Dank, Ahil N. Ganesh, Brian K. Shoichet, Mark Lautens, Molly S. Shoichet
Summary: The pK(a) of colloid-forming drugs can be manipulated to achieve endosomal disruption while avoiding phospholipidosis and minimizing toxicity, leading to the design of drug-rich nanoparticles. By synthesizing ionizable derivatives of fulvestrant analogs, which are lipid-stabilized drug colloids, the pK(a) of these ionizable colloids influenced the mechanism of endosomal and lysosomal disruption. This study establishes a tunable and generalizable strategy for endosomal disruption by manipulating the pK(a) of colloid-forming drugs.
Article
Chemistry, Physical
Patrick T. Probst, Martin Mayer, Vaibhav Gupta, Anja Maria Steiner, Ziwei Zhou, Gunter K. Auernhammer, Tobias A. F. Koenig, Andreas Fery
Summary: This study introduces a scalable bottom-up approach to construct cross-stacked nanoparticle chain arrays with a circular dichroism of up to 11 degrees, showing enhanced sensitivity to chiral analytes. The research demonstrates full control over circular dichroism characteristics and opens up a new pathway towards actively controlled pixel arrays through strain-induced reconfiguration. Stacked elastomeric arrays containing plasmonic nanoparticles exhibit efficient chiral responses that can be fully controlled by mechanical compression and stack rotation, showcasing potential as useful modulators for photonic applications.
Review
Engineering, Environmental
Tianqi Liu, Zhan Li, Juanjuan Wang, Jia Chen, Ming Guan, Hongdeng Qiu
Summary: The separation of chiral compounds, especially enantiomers, is a topic of great interest due to their similar chemical properties and different pharmacological activities. Membrane separation technology, as an emerging method, shows great potential in this field due to its high efficiency, simplicity, low energy consumption, and continuous operation. Various types of chiral solid membranes have been developed from polymer, carbon nanomaterials, metal organic frameworks, and other inorganic materials, but systematic summaries are still lacking.
CHEMICAL ENGINEERING JOURNAL
(2021)
Review
Chemistry, Inorganic & Nuclear
Qingsong Cheng, Qian Ma, Hebing Pei, Hao Liang, Xuejiao Zhang, Xuening Jin, Nijuan Liu, Ruibin Guo, Zunli Mo
Summary: Chirality is a fascinating natural property involved in the origin and evolution of life. Pure enantiomers are crucial for the safety and health of organisms. Chiral metal-organic frameworks have shown great potential in racemic resolution.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Engineering, Chemical
Bangyu Fan, Fujian Li, Yanyan Cheng, Zhongzhi Wang, Nian Zhang, Qingrong Wu, Lu Bai, Xiangping Zhang
Summary: The separation of rare earth elements has always been challenging due to their similar chemical and physical properties. A potential alternative method called magnetic separation, which utilizes the difference in magnetic moment, has shown efficient separation of rare earth elements at room temperature and pressure.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Engineering, Chemical
Bangyu Fan, Fujian Li, Yanyan Cheng, Zhongzhi Wang, Nian Zhang, Qingrong Wu, Lu Bai, Xiangping Zhang
Summary: The separation of rare earth elements has been a challenge due to their chemical and physical similarities. A new method using magnetic field-enhanced crystallization has been developed to efficiently separate these elements at room temperature and pressure.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Physics, Multidisciplinary
Daniel Grober, Ivan Palaia, Mehmet Can Ucar, Edouard Hannezo, Andela Saric, Jeremie Palacci
Summary: The structure and mechanical properties of colloidal aggregates can be controlled by an active bath of swimming Escherichia coli. Passive beads immersed in this bath form unconventional clusters and gels, driven by the activity of the bacteria. The rotation of the aggregates, directed by the chirality of the E. coli flagella, and the internal activity control the phase diagram and structure of the aggregates.
Article
Chemistry, Multidisciplinary
Wesley Flavell, Andreas Neophytou, Angela Demetriadou, Tim Albrecht, Dwaipayan Chakrabarti
Summary: This article presents a method for programmed self-assembly of single colloidal gyroid crystals using rationally designed patchy spheres. The single colloidal gyroid has a wide photonic bandgap and rich chiroptical properties, making it an attractive chiral photonic crystal.
ADVANCED MATERIALS
(2023)
Article
Multidisciplinary Sciences
Mattia Morandi, Monika Kluzek, Jean Wolff, Andre Schroder, Fabrice Thalmann, Carlos M. Marques
Summary: Research has shown that the growth of plastic waste in the natural environment poses a credible and systemic threat to eukaryotic cells, affecting the mechanical properties and thermodynamics of membrane transitions. However, the fundamental mechanisms of interaction between oligomers and polymers with cell components remain unclear.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Chemistry, Multidisciplinary
Vivien Walter, Celine Ruscher, Olivier Benzerara, Fabrice Thalmann
Summary: MLLPA is a Python 3 module that utilizes machine learning tools to analyze lipid membrane phase domains, capable of reading various formats and models of simulation data, and suitable for studying membranes of different geometries.
JOURNAL OF COMPUTATIONAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Helena Junqueira, Andre P. Schroder, Fabrice Thalmann, Andrey Klymchenko, Yves Mely, Mauricio S. Baptista, Carlos M. Marques
Summary: Through experiments and simulations, it was found that organic hydroperoxides migrate to the surface and interior of phospholipid bilayers with different levels of hydroperoxidized lipids. This suggests that lipid peroxidation alters the polarity of biomembranes, thereby significantly impacting the activity of transmembrane proteins and the biomedical efficiency of membrane active molecules.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2021)
Article
Chemistry, Multidisciplinary
Vaibhav Sharma, Carlos M. Marques, Antonio Stocco
Summary: This experiment investigates the interaction between Janus colloids and giant lipid vesicles, demonstrating that external forces can force contact between the particles and the membranes, resulting in partial engulfment. The surface properties of the Janus colloids play a crucial role in this process.
Article
Chemistry, Physical
Yangyang Zhang, Donghui Liu, Yiyang Zhang, Yachong Guo, Wenfei Li, Fabrice Thalmann
Summary: This article describes a coarse-grained model of POPC and DOPC lipid peroxides and discusses their predicted structure and the influence of hydration. In addition, electron and neutron scattering length density profiles of the simulated bilayers are provided.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Miguel Paez-Perez, Aurimas Vysniauskas, Ismael Lopez-Duarte, Eulalie J. J. Lafarge, Raquel Lopez-Rios De Castro, Carlos M. M. Marques, Andre P. Schroder, Pierre Muller, Christian D. D. Lorenz, Nicholas J. J. Brooks, Marina K. K. Kuimova
Summary: Lipid peroxidation plays a crucial role in cell signaling, diseases, and therapy. The authors employed advanced microscopy, X-ray diffraction, and molecular simulations to directly measure the changes in bilayer structure and viscoelastic properties upon peroxidation of lipid membranes.
COMMUNICATIONS CHEMISTRY
(2023)
Article
Physics, Multidisciplinary
Othmene Benazieb, Lisa Berezovska, Fabrice Thalmann
Summary: This paper introduces the Einstein-Sutherland relation in the theory of Brownian motion and the similar Einstein-Helfand relation in classical linear response transport coefficients. By adequately generalizing the Einstein relation, we demonstrate how to derive the interleaflet friction coefficient of lipid bilayers. It is crucial to pay attention to the constraints on the system center of mass position when coupling the system to a thermostat in practical cases.
JOURNAL OF PHYSICS COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Eulalie J. Lafarge, Pierre Muller, Andre P. Schroder, Ekaterina Zaitseva, Jan C. Behrends, Carlos M. Marques
Summary: This paper investigates the electropermeability of model lipid membranes containing different fractions of hydroperoxidized POPC. The results show that the energy barrier to pore formation is linearly related to the absolute value of the electric field, contrary to the predictions of the standard model.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Chemistry, Physical
Vaibhav Sharma, Florent Fessler, Fabrice Thalmann, Carlos M. Marques, Antonio Stocco
Summary: Measuring the rotational and translational Brownian motion of single spherical particles can reveal dissipations due to particle-environment interaction. The experiments conducted in this article demonstrate the measurement of in-plane translational and rotational drag coefficients for a single spherical Brownian particle. These drag coefficients are influenced by particle size, particle-wall distance, and viscous dissipations. Measurements on Janus particles close to solid walls and lipid bilayer membranes reveal that particle-wall distance and size can be determined by hydrodynamic models for particles close to walls. For particles partially wrapped by lipid membranes, when there is no strong binding interaction, translational and rotational drags are significantly larger compared to non-wrapped particles. The dissipations in the deformed membrane cap region also contribute strongly to the drag coefficients.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Physics, Fluids & Plasmas
Dmytro Kushnir, Celine Ruscher, Eckhard Bartsch, Fabrice Thalmann, Pascal Hebraud
Summary: The mechanical nonlinear response of dense Brownian suspensions of polymer gel particles is investigated experimentally and through numerical simulations. The response of the suspension depends on its previous history, including flow starting from a static state and flow reversal. Numerical simulations reveal a delay between the anisotropy of the local microstructure and the macroscopic stress.
Article
Physics, Fluids & Plasmas
Friedrich Walzel, Alice Requier, Kevin Boschi, Jean Farago, Philippe Fuchs, Fabrice Thalmann, Wiebke Drenckhan, Pierre Muller, Thierry Charitat
Summary: Minimal surface problems are important in soft matter systems dominated by surface or interface energies. This study investigates the influence of nonaxisymmetric parallel frame shapes on the shapes, stability, and mechanical properties of minimal surfaces using a perturbation approach. The predictions are validated against experiments and simulations, showing good agreement. The study also reveals the intriguing capacity of minimal surfaces between nonaxisymmetric frames to transmit a mechanical torque despite being completely liquid, indicating potential applications in mechanical self-assembly and force captors.
Article
Chemistry, Physical
Meriem Er-Rafik, Khalid Ferji, Jerome Combet, Olivier Sandre, Sebastien Lecommandoux, Marc Schmutz, Jean-Francois Le Meins, Carlos M. Marques
Summary: Recently, there has been increasing concern about the health risks associated with nanotechnologies, as it has been discovered that nanoparticles can reach the interior of cells and potentially disrupt cell membranes. This study reveals that small nanoparticles can tear lipid membranes, providing insight into the mechanisms by which nanoparticles can compromise membrane integrity.
Article
Physics, Fluids & Plasmas
Othmene Benazieb, Claire Loison, Fabrice Thalmann
Summary: Investigated the friction properties of DSPC lipid bilayer under longitudinal shear, finding significant dependence of membrane mechanical response on physical state, with evidence of linear response in fluid region but not in gel region. Transient viscoelastic response of sheared bilayer accessed, with validity domain of linear response established and timescales discussed.
Article
Chemistry, Physical
Vaibhav Sharma, Elise Azar, Andre P. Schroder, Carlos M. Marques, Antonio Stocco
Summary: The study reveals that active particles exhibit persistent orbital motion around giant lipid vesicles, independent of the sizes of the particles and vesicles. Additionally, force and torque transfers between the active particles and vesicles are described in the experimental investigation. These findings differ from recent reports on interactions between active particles and solid spheres or liquid drops, and may have implications for understanding the interactions of swimming particles with cells in biology or with microplastics in environmental science.
