4.4 Article

Bufavirus in fecal specimens of patients with and without diarrhea in Thailand

期刊

ARCHIVES OF VIROLOGY
卷 160, 期 7, 页码 1781-1784

出版社

SPRINGER WIEN
DOI: 10.1007/s00705-015-2441-z

关键词

Bufavirus; Diarrhea; NS1 gene; Phylogenetic analysis

类别

资金

  1. Ratchadaphisek Somphot Fund
  2. National Research Council of Thailand
  3. Higher Education Research Promotion and National Research University Project of Thailand Office of the Higher Education Commission [WCU-58-006-HR, WCU007-HR57, WCU 001-HR57]
  4. Center of Excellence in Clinical Virology, Chulalongkorn University
  5. Chulalongkorn University Centenary Academic Development Project [CU56-HR01]
  6. Ratchadaphiseksomphot Endowment Fund of Chulalongkorn University [RES560530093]
  7. Outstanding Professor of the Thailand Research Fund [DPG5480002]
  8. National Science and Technology Development Agency
  9. MK restaurant Company Limited
  10. Siam Cement Group PcL
  11. King Chulalongkorn Memorial Hospital

向作者/读者索取更多资源

Bufavirus (BuV) was initially discovered in fecal samples from children with acute diarrhea. In this study, we determined the prevalence, distribution, and genotype(s) of BuV in Thailand. A total of 1,495 diarrheal and 741 non-diarrheal stool specimens were collected and analyzed. A portion of the NS1 gene of BuV was amplified by nested RT-PCR. Phylogenetic analysis was performed to classify the BuV strains found. We detected bufavirus (BuV) in diarrheal (4/1495; 0.27 %) but not in non-diarrheal specimens (0/726). All four strains belonged to BuV genotype 1. BuV could be detected in adults and children, but its role in causing acute diarrhea remains unclear.

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