Article
Immunology
Akashdeep Singh Chauhan, Isha Kapoor, Saroj Kumar Rana, Dilesh Kumar, Madhu Gupta, Jacob John, Gagandeep Kang, Shankar Prinja
Summary: Introduction of TCV in urban areas of India is a cost-saving strategy, with significant prevention of typhoid cases and deaths. However, due to low incidence of typhoid infection, introducing TCV in rural settings of India may not be cost-effective.
Article
Immunology
Dean Langsam, Dor Kahana, Erez Shmueli, Dan Yamin
Summary: The study suggests that adjusting the vaccination schedule can reduce pertussis incidence and healthcare visits, increasing maternal vaccination coverage is cost-effective, while the contribution of the second booster dose is limited.
Article
Immunology
Theresa Ryckman, Arun S. Karthikeyan, Dilesh Kumar, Yanjia Cao, Gagandeep Kang, Jeremy D. Goldhaber-Fiebert, Jacob John, Nathan C. Lo, Jason R. Andrews
Summary: The study suggests that implementing routine and campaign typhoid vaccination strategies in India is cost-saving and highly cost-effective. Combining catch-up campaigns with routine vaccination can prevent millions of cases and save billions of dollars over a 10-year period.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Immunology
Esperanca Lourenco Guimaraes, Assucenio Chissaque, Clint Pecenka, Andrew Clark, Basilia Vaz, Arlindo Banze, Neide Canana, Clesio Romao, Maria do Rosario Oliveira Martins, Nilsa de Deus, Frederic Debellut
Summary: This study aims to evaluate the cost-effectiveness of the ROTARIX vaccine in Mozambique and compare it with other vaccines. The results show that the ROTARIX vaccine had a substantial public health impact between 2016 and 2020.
Review
Immunology
Yoshiyuki Sugishita, Tamie Sugawara
Summary: For elderly individuals with low incidence of influenza, calculating the credible vaccine effectiveness (VE) can be challenging. Current research shows that influenza vaccination for elderly individuals may be cost-effective, but its precise efficacy remains unclear. Studies are ongoing to determine whether influenza vaccination has a high VE for all influenza virus types, and the decreasing effect of repeated vaccination is still debated. Long-term monitoring and analysis are required to evaluate the cost-effectiveness of influenza vaccination for elderly people.
Article
Public, Environmental & Occupational Health
Stephen Okoboi, Barbara Castelnuovo, Jean-Pierre Van Geertruyden, Oucul Lazarus, Lung Vu, Sam Kalibala, Yvonne Kamara, Perez N. Ochanda, Rachel King, Andrew Mujugira
Summary: Distribution of HIV self-testing kits through MSM peer networks is a cost-effective strategy to increase HIV testing coverage in high-risk populations, leading to the identification of more undiagnosed HIV infections. The cost per new HIV diagnosis and cost per transmission averted were lower for the intervention approach compared to standard-of-care hotspot testing, making it a more efficient option for HIV testing in sub-Saharan Africa.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Huixuan Zhou, Ningxin Ding, Xueyan Han, Hanyue Zhang, Zeting Liu, Xiao Jia, Jingjing Yu, Wei Zhang
Summary: This study evaluates the cost-effectiveness of the current COVID-19 vaccination strategy among the general population in mainland China. The findings show that vaccination reduces infection and death rates, saves healthcare costs, and is considered a cost-effective strategy.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Immunology
Arnold Hagens, Ahmet Cagkan Inkaya, Kasirga Yildirak, Mesut Sancar, Jurjen van der Schans, Aylin Acar Sancar, Serhat Unal, Maarten Postma, Selen Yegenoglu
Summary: The study indicates that COVID-19 vaccination in Turkey is highly cost-effective or even cost-saving from both healthcare and societal perspectives. The minimum required vaccine uptake for cost-effectiveness is at least 30%, with sensitivity and scenario analyses showing robust results.
Article
Immunology
Coralei E. Neighbors, Evan R. Myers, Nayani P. Weerasinghe, Gaya B. Wijayaratne, Champica K. Bodinayake, Ajith Nagahawatte, L. Gayani Tillekeratne, Christopher W. Woods
Summary: Influenza vaccination is cost-effective for the Sri Lankan population, reducing cases, hospitalizations, and deaths caused by influenza. The most influential factors are vaccine coverage and effectiveness in different age groups. Providing influenza vaccines is highly cost-effective compared to not vaccinating. However, more large-scale national studies are needed to improve data and assess the impact of vaccination implementation.
Article
Multidisciplinary Sciences
Krishna P. Reddy, Kieran P. Fitzmaurice, Justine A. Scott, Guy Harling, Richard J. Lessells, Christopher Panella, Fatma M. Shebl, Kenneth A. Freedberg, Mark J. Siedner
Summary: Cost, supply, and logistics are challenges for COVID-19 vaccine rollout in low and middle-income countries. Modeling a vaccination program in South Africa, the study demonstrates the importance of a rapid vaccine rollout in preventing infections and deaths, even with moderately efficacious vaccines. Implementing prompt vaccination procurement, distribution, and rollout could provide high value and decrease both deaths and healthcare costs across a wide range of assumptions.
NATURE COMMUNICATIONS
(2021)
Article
Economics
Pieter T. de Boer, Lisa Nagy, Franklin C. K. Dolk, Jan C. Wilschut, Richard Pitman, Maarten J. Postma
Summary: The study concludes that introducing pediatric influenza vaccination in the Netherlands is cost-saving and significantly reduces the burden of influenza-related diseases. The model suggests that adding pediatric vaccination for 2-17-year-olds to the current vaccination program for elderly and high-risk groups could lead to substantial reductions in symptomatic infections and deaths.
Review
Immunology
Giuseppe Santoli, Mario Cesare Nurchis, Giovanna Elisa Calabro, Gianfranco Damiani
Summary: SARS-CoV-2 vaccination has proven highly effective in preventing COVID-19, reducing global deaths and hospitalizations. While vaccine distribution remains unequal, it is crucial to organize mass vaccination campaigns worldwide to control the spread of the virus. This systematic review confirms that COVID-19 vaccination campaigns are cost-effective and sustainable public health measures in fighting the pandemic.
Article
Public, Environmental & Occupational Health
Ryan R. Thompson, Talemwa Nalugwa, Denis Oyuku, Austin Tucker, Mariam Nantale, Annet Nakaweesa, Johnson Musinguzi, Tania F. Reza, Alexandra J. Zimmer, Olivia Ferguson, Stavia Turyahabwe, Moses Joloba, Adithya Cattamanchi, Achilles Katamba, David W. Dowdy, Hojoon Sohn
Summary: This study evaluated the cost and cost-effectiveness of a multicomponent strategy including decentralised molecular testing for tuberculosis in Uganda. The results showed that the strategy facilitated higher rates of tuberculosis testing and had a modest incremental cost.
LANCET GLOBAL HEALTH
(2023)
Article
Immunology
Holly Burrows, Marina Antillon, Jillian S. Gauld, Jong-Hoon Kim, Vittal Mogasale, Theresa Ryckman, Jason R. Andrews, Nathan C. Lo, Virginia E. Pitzer
Summary: Mathematical models compared different strategies for typhoid vaccination and predicted the expected outcomes. The results showed that routine vaccination and catch-up campaigns can reduce the incidence of typhoid in high burden areas and are cost-effective.
Article
Economics
Ryan R. Thompson, Alex Kityamuwesi, Alice Kuan, Denis Oyuku, Austin Tucker, Olivia Ferguson, Lynn Kunihira Tinka, Rebecca Crowder, Stavia Turyahabwe, Adithya Cattamanchi, David W. Dowdy, Achilles Katamba, Hojoon Sohn
Summary: This study evaluated the cost and cost-effectiveness of implementing the digital adherence technology 99DOTS in a high-TB-burden setting. The results showed that the costs and cost-effectiveness of 99DOTS were influenced by the scale of infrastructure over time. If sustained and scaled up, 99DOTS can be a cost-effective option for TB treatment adherence support in high-TB-burden settings.