Article
Materials Science, Multidisciplinary
Xiaoyu Ning, Si Chen, Yating Yang, Jangsun Hwang, Christian Wiraja, Chi Zhang, Wei Liu, Linbo Liu, Chenjie Xu
Summary: This research introduces a new technique using the frozen immersion method to load drugs on bubble-generating microneedles, which enhances drug delivery efficiency by producing bubbles to improve drug transportation, combined with sonophoresis to further increase the efficiency of transdermal drug delivery.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Fisheries
Yingli Gao, Lu Qiang, Liyuan Zhang, Ruiming Tan, Xingqiang Wang, Yongxiang Yu
Summary: This study investigated the mucosal and humoral immune responses of javelin goby to immersion vaccination with Vibrio vulnificus bacterin. The results showed that serum antibody titers increased gradually after vaccination, while mucosal antibody titers in the gill, skin, and intestine showed a faster response. Antigen uptake was significantly enhanced in mucosa-associated tissues compared to other organs. The histological results indicated an increase in mucous cell numbers in mucosa-associated tissues, with a shift in mucin components. These findings provide valuable information on mucosal immunity in fish and highlight the advantage of immersion vaccines in eliciting a high level of local immune response.
AQUACULTURE INTERNATIONAL
(2023)
Article
Agriculture, Dairy & Animal Science
Katarzyna Dziewulska, Lucyna Kirczuk, Robert Czerniawski, Monika Kowalska-Goralska
Summary: The study demonstrates that selenium supplementation of fertilized eggs can improve breeding outcomes in fish in selenium-poor areas. Adequate selenium intake benefits the health and growth of organisms, while overdose can be harmful. Selenium concentration should be adjusted based on the chemical compound, fish species, and selenium content in the yolk.
Article
Psychology, Psychoanalysis
Stacey L. Novack
Summary: The author responds to the critique of Milner's plunge metaphor by Corbett and Stephens, emphasizing that the movements inward and outward are central to creative life. She argues that creative experience emerges from transitionality rather than relationality, and clarifies the contributions of British Independent group theorists in this area.
PSYCHOANALYTIC DIALOGUES
(2021)
Article
Multidisciplinary Sciences
Junhua Xu, Hongwei Cai, Zhuhao Wu, Xiang Li, Chunhui Tian, Zheng Ao, Vivian C. Niu, Xiao Xiao, Lei Jiang, Marat Khodoun, Marc Rothenberg, Ken Mackie, Jun Chen, Luke P. Lee, Feng Guo
Summary: We have developed an active acoustic metamaterials-driven transdermal drug delivery method for rapid and on-demand management of acute diseases. This method integrates compact therapeutic patches with precise control of drug dosage and release kinetics, providing better delivery performance than subcutaneous injection. As a proof-of-concept, our method successfully reverses acute allergic reactions in a mouse model, demonstrating its potential for personalized medicine.
NATURE COMMUNICATIONS
(2023)
Article
Engineering, Chemical
Miaomiao Tian, Hellen De Coninck, Junyong Zhu, Yatao Zhang, Shushan Yuan, Brecht Van Hooreweder, Peter Van Puyvelde, Bart Van der Bruggen
Summary: The study explored the feasibility of using 3D printed membranes in membrane distillation for the first time, and results showed that coating polyamide membranes with poly(vinylidene fluoride) layers effectively reduced pore size. However, the relatively thick 3D printed membranes, despite their greater hydrophobicity compared to PVDF membranes, significantly affected membrane properties and MD performance.
Review
Pharmacology & Pharmacy
Olimpia Dumitriu Buzia, Ana Maria Paduraru, Claudia Simona Stefan, Monica Dinu, Dorin Ioan Cocos, Lawrence Chukwudi Nwabudike, Alin Laurentiu Tatu
Summary: In this work, various strategies to enhance transdermal drug delivery, such as iontophoresis, sonophoresis, electroporation and micron, are explored. A review on transdermal patches and their medical applications is also presented. The paper introduces new approaches for controlled drug release including niosomes, microemulsions, transfersomes, ethosomes, as well as hybrid approaches such as nanoemulsions and microns. The novelty of this review lies in the combination of strategies to improve transdermal drug administration with their applications in medicine, in the context of pharmaceutical technological advancements.
Article
Green & Sustainable Science & Technology
Chunxia Yang, Qian Li, Xueyuan Hu, Yuan Zheng, Jiawei Wu, Shengzhi Su, An Yu
Summary: This study evaluates the performance, efficiency, and fish-friendliness of ultra-low head undershot fixed-blade and flip-blade waterwheels through numerical simulations. The accuracy of the fixed-blade waterwheel simulation is verified, and the fish injury likelihood is predicted. The results show that the waterwheel is fish-friendly and the flip-blade waterwheel has higher efficiency under the same working conditions.
Article
Pharmacology & Pharmacy
Akeemat O. Tijani, Amruta A. Dandekar, Tanvi Karve, Ajay K. Banga, Ashana Puri
Summary: This study investigated the feasibility of using minimally invasive physical ablative techniques for delivering naloxone via the skin. These techniques reduced the lag time to naloxone delivery and significantly increased the amount of naloxone delivered in 1 h and over 24 h compared to passive delivery. Sonophoresis and laser showed the highest delivery in 1 h, followed by dermaplaning. However, there were inconsistencies in the in vitro permeation profile of naloxone with the ultrasound frequency used. With proper optimization, these techniques can potentially be applied for systemic naloxone delivery in opioid emergencies and disaccustoming purposes.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Multidisciplinary Sciences
Kaela Navarro, Katechan Jampachaisri, David Chu, Cholawat Pacharinsak
Summary: This study investigated the efficacy of using bupivacaine immersion for euthanasia of African Clawed frogs. The results showed that after 1-hour immersion, animals treated with Bupi-1.5 had decreased heart rates. After 5-hour immersion, animals treated with Bupi-1.5 and TMS-5 had comparable heart rates. We recommend 19-hour immersion with either TMS-5 or Bupi-1.5 for cessation of heart rate in African Clawed frogs.
Review
Health Care Sciences & Services
Francisco Javier Martin-Vega, Maria Jesus Vinolo-Gil, Veronica Perez-Cabezas, Manuel Rodriguez-Huguet, Cristina Garcia-Munoz, Gloria Gonzalez Medina
Summary: This study conducted a meta-analysis to compare the use of phonophoresis with corticosteroids to other non-surgical treatment methods for carpal tunnel syndrome. The results showed that phonophoresis with corticosteroids may be an effective treatment method for reducing pain and improving motor and sensory nerve conduction in mild to moderate cases of carpal tunnel syndrome.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Mohamed Emam, Khalil Eslamloo, Albert Caballero-Solares, Evandro Kleber Lorenz, Xi Xue, Navaneethaiyer Umasuthan, Hajarooba Gnanagobal, Javier Santander, Richard G. Taylor, Rachel Balder, Christopher C. Parrish, Matthew L. Rise
Summary: This study investigates the immunomodulatory effects of different levels of dietary omega-6/omega-3 fatty acids on Atlantic salmon. The results show that the dietary fatty acid profile can affect the salmon's antibacterial response to pathogens, and different dietary regimens may have an impact on the expression of immune-related genes. This research provides a new direction for studying the immune response of fish to pathogens using high omega-6/high omega-3 diets.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Geochemistry & Geophysics
Wei Chen, Hang Wang, Liuqing Yang, Xingye Liu, Yangkang Chen
Summary: This article introduces an improved slope estimation method based on the plane-wave destruction theory, which is more robust to noise and accurately calculates the first-order derivative in the space domain using forward-backward finite-difference calculation. Nonstationary smoothing is also introduced to enhance the robustness of slope estimation.
Article
Geochemistry & Geophysics
Shangsheng Yan, Xinming Wu
Summary: The method presented in this study offers an efficient algorithm for optimizing and extracting horizons in seismic images, allowing for more accurate tracking across faults and noise, and revealing more geological details.
Article
Microbiology
Eduarda Alexandra Goncalves de Oliveira Moura, Daniela Gomes da Silva, Caio Henrique Turco, Thainara Vitoria Carnevalli Sanches, Gabriel Yuri Storino, Henrique Meiroz de Souza Almeida, Marina Lopes Mechler-Dreibi, Isabela Peixoto Rabelo, Karina Sonalio, Luis Guilherme de Oliveira
Summary: This study aimed to evaluate the efficacy of vaccination with Salmonella Choleraesuis and Salmonella Typhimurium bacterins in pigs. The results showed that this vaccine partially protected the animals against experimental infection with Salmonella Typhimurium, reducing the excretion of bacteria in feces.
Article
Fisheries
Thao Thu Mai, Pattanapon Kayansamruaj, Suwimon Taengphu, Saengchan Senapin, Janina Z. Costa, Jorge del-Pozo, Kim D. Thompson, Channarong Rodkhum, Ha Thanh Dong
Summary: The study developed heat-killed and formalin-killed vaccines for prevention of Tilapia tilapinevirus disease, with both vaccines showing significant protection and different gene expressions in the immune response.
JOURNAL OF FISH DISEASES
(2021)
Review
Microbiology
Maria Chiara Cascarano, Orestis Stavrakidis-Zachou, Ivona Mladineo, Kim D. Thompson, Nikos Papandroulakis, Pantelis Katharios
Summary: Climate change will have a significant impact on global aquaculture, especially in the Mediterranean Sea. Rising temperatures will affect fish farming and potentially lead to an increase in disease outbreaks, resulting in severe economic losses for aquaculture systems.
Article
Fisheries
Sean J. Monaghan, Diana Chee, Alexandra Adams, Sven M. Bergmann, Shin M. Chong, Jing Chen, Kim D. Thompson
Summary: The study found that only 31% of koi from PCR-positive KHV fish groups were seropositive in ELISA testing. Furthermore, over 34% of seropositive but PCR-negative fish had titres of >1/400. These results highlight the concerns related to carp populations that have been screened for KHV using molecular methods alone and emphasize the need for serology to accompany molecular testing in carp for this notifiable virus.
Review
Fisheries
Matthijs Metselaar, Massimo Orioles, Marco Galeotti, Alexandra Adams, Kim D. Thompson
Summary: Red mark syndrome (RMS) is a skin condition affecting rainbow trout aquaculture, first reported in the United States and subsequently spreading to other parts of the world. It causes economic loss to the industry and has been associated with two pathogens, although the exact cause is still unknown.
Article
Biotechnology & Applied Microbiology
Ae Rin Lee, Seong Bin Park, Si Won Kim, Jae Wook Jung, Jin Hong Chun, Jaesung Kim, Young Rim Kim, Jassy Mary S. Lazarte, Ho Bin Jang, Kim D. Thompson, Myunghwan Jung, Min Woo Ha, Tae Sung Jung
Summary: The study demonstrates that membrane vesicles (MVs) from Gram-positive bacteria are capable of transferring beta-lactam antibiotic-resistant substances to antibiotic-sensitive Gram-negative bacteria, resulting in increased resistance to beta-lactam antibiotics.MVs play a role in transferring substances from Gram-positive to Gram-negative bacteria, shown by the release of MVs from RC85-T that were able to protect beta-lactam-susceptible bacteria from beta-lactam antibiotics.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Fisheries
R. Hoare, K. Shahin, K. McLean, A. Adams, K. D. Thompson
JOURNAL OF FISH DISEASES
(2022)
Article
Immunology
Thao Thu Mai, Pattanapon Kayansamruaj, Chayanit Soontara, Pattarawit Kerddee, Dinh-Hung Nguyen, Saengchan Senapin, Janina Z. Costa, Jorge del-Pozo, Kim D. Thompson, Channarong Rodkhum, Ha Thanh Dong
Summary: Immunization of tilapia broodstock with TiLV vaccines can induce antibody response and transfer maternal antibodies to fertilized eggs and larvae, providing protection against TiLV. HKV appears to be more promising than FKV for maternal vaccination.
Article
Fisheries
Ana Herrero, Oswaldo Palenzuela, Hamish Rodger, Chris Matthews, Mar Marcos-Lopez, James E. Bron, Mark P. Dagleish, Kim D. Thompson
Summary: The microsporidian D. lepeophtherii is difficult to detect in tissue sections, and this study developed an ISH protocol specific for D. lepeophtherii, which showed higher sensitivity compared to other methods.
JOURNAL OF FISH DISEASES
(2022)
Article
Microbiology
Seong Bin Park, Yon Kyoung Park, Min Woo Ha, Kim D. Thompson, Tae Sung Jung
Summary: Pathogenic typing, molecular typing, and antimicrobial susceptibility tests were conducted on 75 isolates of E. coli from stool samples of patients suffering from foodborne diseases in Busan, South Korea. The isolates showed high resistance to certain antibiotics but high susceptibility to others, indicating a high level of heterogeneity between the E. coli isolates.
Article
Microbiology
Ana Herrero, Hamish Rodger, Adam D. Hayward, Chris Cousens, James E. Bron, Mark P. Dagleish, Kim D. Thompson
Summary: Complex gill disorder (CGD) is an important condition in Atlantic salmon aquaculture, but the roles of the putative aetiological agents in the pathogenesis are uncertain. This study shows that the loads of certain pathogens are significantly associated with the severity of CGD, and water temperature and management factors also have an impact on gill lesions.
Review
Fisheries
Bei Wang, Kim D. Thompson, Eakapol Wangkahart, Jidapa Yamkasem, Melba G. Bondad-Reantaso, Puntanat Tattiyapong, Jianchang Jian, Win Surachetpong
Summary: In recent years, emerging and re-emerging diseases have had a significant economic impact on the tilapia industry. Without effective management and appropriate biosecurity measures, infectious diseases will continue to challenge the sustainability of global tilapia aquaculture. Enhancing immune response and improving husbandry management can help reduce the impact of diseases.
REVIEWS IN AQUACULTURE
(2023)
Article
Fisheries
Anurak Bunnoy, Kim D. Thompson, Patcharapong Thangsunan, Putita Chokmangmeepisarn, Teerapong Yata, Nopadon Pirarat, Sirikorn Kitiyodom, Pattanapong Thangsunan, Pimwarang Sukkarun, Pochara Prukbenjakul, Naphat Panthukumphol, Manami Morishita, Prapansak Srisapoome, Channarong Rodkhum
Summary: A new bivalent mucoadhesive nanovaccine was developed for immersion vaccination of tilapia against francisellosis and columnaris disease. It has the potential to improve innate and adaptive immunity in vaccinated fish, increasing survival rates.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Review
Immunology
Kim D. Thompson, Channarong Rodkhum, Anurak Bunnoy, Patcharapong Thangsunan, Sirikorn Kitiyodom, Pimwarang Sukkarun, Jakarwan Yostawornkul, Teerapong Yata, Nopadon Pirarat
Summary: Tilapia is extensively farmed and provides an important source of food and income for low-income families. However, disease outbreaks caused by bacteria and viruses have increased with the intensification of farming systems. Nanoparticle-based vaccines offer potential solutions to improve vaccine acceptance and uptake among tilapia farmers.
Article
Fisheries
Mariana Vaz, Damiana Pires, Pedro Pires, Marco Simoes, Ana Pombo, Paulo Santos, Beatriz do Carmo, Ricardo Passos, Janina Z. Costa, Kim D. Thompson, Teresa Baptista
Summary: The early host-pathogen interaction between European seabass and Betanodavirus was examined by infecting juvenile fish with RGNNV. The study found that the host's immune system was activated shortly after infection, and significant changes in hematological, antioxidant, and immunological responses were observed. Furthermore, the peak expression of certain immune markers coincided with disease symptoms and high levels of fish mortality.
Review
Food Science & Technology
Stacia Stetkiewicz, Rachel A. Norman, Edward Hugh Allison, Neil L. Andrew, Gulshan Ara, Gill Banner-Stevens, Ben Belton, Malcolm Beveridge, Jessica R. Bogard, Simon R. Bush, Pete Coffee, Margaret Crumlish, Peter Edwards, Mahmoud Eltholth, Lynne Falconer, Joao G. Ferreira, Angus Garrett, Iain Gatward, Faruk U. Islam, Alexander M. Kaminski, Marian Kjellevold, Froukje Kruijssen, William Leschen, Abdullah-Al Mamun, Bruce McAdam, Richard Newton, Birgitte Krogh-Poulsen, Alexandra Pounds, Belinda Richardson, Nanna Roos, Elin Roeoes, Andrea Schapper, Tori Spence-McConnell, Sharon K. Suri, Shakuntala Haraksingh Thilsted, Kim D. Thompson, Michael F. Tlusty, Max Fredrik Troell, Raffaele Vignola, James A. Young, Wenbo Zhang, David C. Little
Summary: This review assesses the representation of seafood in recent food security literature and finds that seafood is under-researched compared to terrestrial production systems. The study also reveals a lack of research on the interaction between terrestrial and aquatic systems. Therefore, there is a need for more attention to be given to the role of seafood in global food security and for its integration into interdisciplinary research.
FRONTIERS IN SUSTAINABLE FOOD SYSTEMS
(2022)
