期刊
VACCINE
卷 33, 期 25, 页码 2917-2921出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2015.04.063
关键词
A(H1N1)pdm09 influenza; Influenza vaccines; Vaccine effectiveness; Children; Prior vaccination
资金
- Guangdong Provincial Department of Science and Technology [2012B091100045]
In 2012-2013, we examined 1729 laboratory-confirmed A(H1N1)pdm09 influenza cases matched 1:1 with healthy controls and estimated influenza vaccine effectiveness (VE) for trivalent inactivated influenza vaccine (IIV3) to be 67% (95% confidence interval = 58-74%) for ages 8 months to 6 years old. Among children aged 8-35 months old, VE for fully vaccinated children (73%, 60-81%) was significantly higher than VE for partially vaccinated children (55%, 33-70%). Significant cross-season protection from prior IIV3 was noted, including VE of 31% (8-48%) from IIV3 received in 2010-2011 against influenza illness in 2012--2013 without subsequent boosting doses. Published by Elsevier Ltd.
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