Article
Virology
Yeeun Kim, Kyung Min Lee, Guehwan Jang, Changhee Lee
Summary: This study reports the genome sequence and molecular characterization of a novel PHEV strain, GNU-2113, identified in diarrheic neonates in South Korea. The strain shows low similarity to existing PHEV genotypes, indicating significant evolution under endemic pressure.
ARCHIVES OF VIROLOGY
(2022)
Article
Virology
Se Eun Kim, Davaajargal Igori, Suk-Yoon Kwon, Jae Sun Moon
Summary: The complete genome sequence of a putative new virus isolate, provisionally named Fagopyrum esculentum endornavirus 2 (FeEV2), shows low nucleotide and amino acid sequence identity with other known endornaviruses. FeEV2 is likely a new species within the Alphaendornavirus genus.
ARCHIVES OF VIROLOGY
(2022)
Article
Virology
Yang Chan Park, Kwang-Kyu Kim, Hyun Jeong Jun, Eun-Ha Kang, Su-Rim Lee, Jun Ki Ahn, Han Kyu Seo, Su-Heon Lee, Kwang-Lae Hoe
Summary: We identified a novel virus, named cnidium polerovirus 1 (CnPV1), that infects Cnidium officinale. The complete genome sequence of CnPV1 is 6,090 nucleotides long and shows similarity to other poleroviruses. Phylogenetic analysis suggests that CnPV1 belongs to a new species within the genus Polerovirus.
ARCHIVES OF VIROLOGY
(2023)
Article
Infectious Diseases
Jonghyun Park, Hye-Ryung Kim, Jong-Min Kim, Kyoung-Ki Lee, Won-Il Kim, Young S. Lyoo, Oh-Deog Kwon, Choi-Kyu Park, Seung-Chun Park
Summary: Porcine respirovirus 1 (PRv1) is an emerging pig respiratory virus that has been found to be widely distributed in Korean pig herds. Genetic analysis suggests that the Korean PRv1 strains are closely related to strains from Hong Kong, Germany and Poland.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Virology
Davaajargal Igori, Seungmo Lim, Hye Sun Cho, Hyun-Soon Kim, Jeong Mee Park, Hyo-Jun Lee, Kee-Jong Hong, Suk-Yoon Kwon, Jae Sun Moon
Summary: The complete genome sequence of a new polerovirus, ArtVB, infecting Artemisia princeps was determined. It shares nucleotide sequence identity with another virus, IxYMaV-1, but differs in amino acid sequences from other poleroviruses. Phylogenetic analysis suggests that ArtVB should be classified as a new species within the genus Polerovirus.
ARCHIVES OF VIROLOGY
(2021)
Article
Veterinary Sciences
Wei Zhao, Jialei Shi, Yongxiu Yao, Hongxia Shao, Aijian Qin, Kun Qian
Summary: This study successfully isolated and molecularly characterized two strains of Chicken astrovirus (CAstV), and observed their effect on hatchability. The genetic analysis showed that these two strains had typical characteristics of avian astroviruses, with high similarity among Chinese strains and a common origin with strains from the UK.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Virology
Sook-Young Lee, Jong-Ho Kim, Yoon-Ji Kim, Young-Sik Kim, Su-Gwon Roh, Kyung-Hyun Lee, Heui-Jin Kim, Jae-Ho Shin, Jae-Ku Oem
Summary: A neuroinvasive astrovirus (BoAstV 20B05) was discovered in a Korean native cattle with neurological symptoms, showing lymphocyte infiltration and high viral genome concentration in the brain tissues. Evolutionary analysis revealed its classification into the NeuroS1 sub-lineage and independent evolution from BoAstV KagoshimaSR28-462, suggesting its first introduction in Korea.
Article
Agriculture, Dairy & Animal Science
Seon Young Park, In Hwang Kim, Hyun Jin Yu, Hyoung Rok Paik, Jee Soo Son, Ji Hyung Kim
Summary: The study analyzed the genome of Streptococcus suis strain INT-01 isolated from a domestic pig in Korea, revealing that its capsular polysaccharide synthesis locus is almost identical to a strain from China, suggesting they can be classified as serotype 3. This genotype, an epf(-)/mrp(+)/sly(-) S. suis, is the most prevalent in Korea, and contains virulence-related genes linked to the pathogenicity of S. suis.
JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY
(2021)
Article
Infectious Diseases
Duri Lee, Sangjune Shin, Guehwan Jang, Yunhee Gim, Hyun-Kyoung Son, Sang Chul Kang, Yongjoon Eo, Young-Gook Chae, Phil-Ok Koh, Hu-Jang Lee, Changhee Lee
Summary: This study isolated a novel porcine deltacoronavirus (PDCoV) strain that caused a severe diarrhea outbreak with a high mortality rate among neonatal piglets in South Korea. Experimental infection showed that the virulence of the novel strain was enhanced compared to previous strains, causing severe clinical symptoms and high mortality in piglets.
TRANSBOUNDARY AND EMERGING DISEASES
(2023)
Article
Virology
Rachelle Bester, Leonidas Lotos, Abraham Vermeulen, Gerhard Pietersen, Varvara I. Maliogka, Hans J. Maree
Summary: High-throughput sequencing was utilized to analyze the virome profile of a grapevine infected with grapevine leafroll disease, revealing a virus sequence similar to those of the genus Badnavirus. The complete genome sequence of this virus, a divergent variant of grapevine Roditis leaf discoloration-associated virus (GRLDaV), was identified with 90% nucleotide sequence identity to an isolate from South African variant.
ARCHIVES OF VIROLOGY
(2021)
Article
Microbiology
Tuvshinzaya Damdintogtokh, In-Tae Cha, Myung Kyum Kim
Summary: Two novel strains BT594(T) and BT646(T) of the genus Hymenobacter, isolated from soil in South Korea, show a high similarity in their 16S rDNA sequences and can be suggested as two new species, named Hymenobacter guriensis and Hymenobacter duratus, respectively, based on polyphasic analysis.
CURRENT MICROBIOLOGY
(2021)
Article
Microbiology
Qinghe Zhu, Yan Miao, Jun Wang, Wenfei Bai, Xu Yang, Shiping Yu, Donghua Guo, Dongbo Sun
Summary: Since November 2016, severe infectious diseases characterized by gout and kidney swelling caused by goose astrovirus (GoAstV) have affected goslings in major goose-producing areas in China. In 2021, a similar outbreak occurred in commercial goose farms in Heilongjiang Province, China. A strain named HLJ2021 was successfully isolated, and it belongs to GoAstV-2 (G2). This strain showed high pathogenicity in goslings, leading to a high mortality rate.
VETERINARY MICROBIOLOGY
(2022)
Article
Veterinary Sciences
Junqin Zhang, Yunzhen Huang, Linlin Li, Jiawen Dong, Ruihuan Kuang, Ming Liao, Minhua Sun
Summary: A novel duck astrovirus, designated as DAstV-5 JM strain, was identified in a fatal disease outbreak in domestic ducks. This DAstV represents a new genotype species of avastrovirus, with low sequence similarities to other known avastroviruses.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Plant Sciences
Zhengying Cao, Linyi Yang, Yaxuan Xin, Wenbin Xu, Qishao Li, Haorong Zhang, Yuxiang Tu, Yu Song, Peiyao Xin
Summary: This study conducted comparative genomic and phylogenetic analyses on seven Neocinnamomum taxa, revealing the genetic structure and evolutionary characteristics of these species. The chloroplast genome of Neocinnamomum has a size range of 150,753-150,956 bp and contains 128 annotated genes. The study identified 31 preferred codons and three highly variable regions. The results of this study will serve as a reference for molecular marker development and phylogenetic research in Neocinnamomum.
FRONTIERS IN PLANT SCIENCE
(2023)
Review
Infectious Diseases
Gyoungsik Kang, Won-Sik Woo, Kyung-Ho Kim, Ha-Jeong Son, Min-Young Sohn, Ju-Won Kim, Chan-Il Park
Summary: Decapod iridescent virus 1 (DIV1) is a dangerous virus that causes mortality in shrimp and crayfish. It has been reported in China, a major exporter of decapods to South Korea and neighboring countries. South Korea has conducted emergency quarantine for DIV1 since 2020 based on import risk analysis, following international and domestic laws and regulations.
TRANSBOUNDARY AND EMERGING DISEASES
(2023)
Article
Virology
Sunhee Lee, Youngnam Kim, Changhee Lee
Article
Immunology
Pil-Soo Baek, Hwan-Won Choi, Sunhee Lee, In-Joong Yoon, Young Ju Lee, Du Sik Lee, Seungyoon Lee, Changhee Lee
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
(2016)
Article
Microbiology
Seung-Chul Lee, Hwan-Won Choi, Eeuri Nam, Yun-Hee Noh, Sunhee Lee, Yoo Jin Lee, Gun-Seok Park, Jae-Ho Shin, In-Joong Yoon, Shien-Young Kang, Changhee Lee
VETERINARY MICROBIOLOGY
(2016)
Article
Microbiology
Sunhee Lee, Kyu-Yeol Son, Yun-Hee Noh, Seung-Chul Lee, Hwan-Won Choi, In-Joong Yoon, Changhee Lee
VETERINARY MICROBIOLOGY
(2017)
Article
Veterinary Sciences
Seung-Chul Lee, Sunhee Lee, Gun-Woo Yoo, Hwan-Won Choi, Yun-Hee Noh, Chang Eon Park, Jae-Ho Shin, In-Joong Yoon, Shien-Young Kang, Changhee Lee
JOURNAL OF VETERINARY SCIENCE
(2018)
Article
Infectious Diseases
Sunhee Lee, Changhee Lee
TRANSBOUNDARY AND EMERGING DISEASES
(2018)
Article
Infectious Diseases
Sunhee Lee, Changhee Lee
TRANSBOUNDARY AND EMERGING DISEASES
(2019)
Article
Infectious Diseases
Sunhee Lee, Dong-Uk Lee, Yun-Hee Noh, Seung-Chul Lee, Hwan-Won Choi, Hyoung-Seok Yang, Jun-Ho Seol, Seong Hwan Mun, Won-Myoung Kang, Hyekyung Yoo, Changhee Lee
TRANSBOUNDARY AND EMERGING DISEASES
(2019)
Review
Biotechnology & Applied Microbiology
Dae-Gyun Ahn, Hye-Jin Shin, Mi-Hwa Kim, Sunhee Lee, Hae-Soo Kim, Jinjong Myoung, Bum-Tae Kim, Seong-Jun Kim
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
(2020)
Article
Virology
Dae-Gyun Ahn, Gun Young Yoon, Sunhee Lee, Keun Bon Ku, Chonsaeng Kim, Kyun-Do Kim, Young-Chan Kwon, Geon-Woo Kim, Bum-Tae Kim, Seong-Jun Kim
Summary: Recent outbreaks of zoonotic coronaviruses, such as MERS-CoV and SARS-CoV-2, have caused significant casualties and economic shock. A novel compound, KCB261770, has been identified to effectively inhibit MERS-CoV frameshifting, showing potential as a drug candidate for interfering with pan-coronavirus frameshifting.
Article
Veterinary Sciences
Guehwan Jang, Sunhee Lee, Changhee Lee
Summary: The study constructed an assessment model to evaluate the biosecurity, herd immunity, and virus circulation status in PEDV-infected farms. Results indicated a risk of recurrent outbreaks in these farms due to lax biosecurity, incomplete immunity in sows, and virus circulation, highlighting the importance of proactive measures to reduce the risk of recurrence.
JOURNAL OF VETERINARY SCIENCE
(2021)
Article
Virology
Sunhee Lee, Changhee Lee
ARCHIVES OF VIROLOGY
(2017)
Article
Biochemistry & Molecular Biology
Hye Jin Shin, Keun Bon Ku, Hae Soo Kim, Hyun Woo Moon, Gi Uk Jeong, Insu Hwang, Gun Young Yoon, Sunhee Lee, Sumin Lee, Dae-Gyun Ahn, Kyun-Do Kim, Young-Chan Kwon, Bum-Tae Kim, Seong-Jun Kim, Chonsaeng Kim
Summary: COVID-19, caused by the novel coronavirus SARS-CoV-2, poses a serious global threat and there is an urgent need to develop treatments. Research has shown that the receptor-binding domains (RBDs) in the spike protein of SARS-CoV and MERS-CoV have antiviral activity, and now recombinant SARS-CoV-2 RBD proteins are found to have potential antiviral efficacy for prevention and treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Immunology
Sunhee Lee, Gun Young Yoon, Jinjong Myoung, Seong-Jun Kim, Dae-Gyun Ahn
EMERGING MICROBES & INFECTIONS
(2020)