期刊
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
卷 13, 期 21, 页码 9978-9981出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cp02832k
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资金
- ETH [ETH-09 10-1]
Lipid domains in supported lipid layers serve as a popular model to gain insight into the processes associated with the compartmentalization of biological membranes into so-called lipid rafts. In this paper, we present reproducible tip-enhanced Raman spectra originating from a very small number of molecules in a lipid monolayer on a gold surface, probed by the apex of a nanometer-sized silver tip. For the first time, we show large (128 x 128 pixels), high-resolution (<50 nm) tip-enhanced Raman images of binary lipid mixtures with full spectral information at each pixel.
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