☆ 4.4 Article

Efficient Singlet Oxygen Generation by Luminescent 2-(2′-Thienyl)Pyridyl Cyclometalated Platinum(II) Complexes and Their Calixarene Derivatives

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2010)

期刊

PHOTOCHEMISTRY AND PHOTOBIOLOGY

卷 86, 期 6, 页码 1414-1420

出版社

WILEY

DOI: 10.1111/j.1751-1097.2010.00809.x

关键词

-

类别

Biochemistry & Molecular Biology Biophysics

资金

Research Grant Council of the Hong Kong SAR, China [HKU 7030/06P]
University of Hong Kong
Chinese Academy of Sciences-Croucher Foundation
National Natural Science Foundation of China/Research Grants Council [N_HKU 752/08]
NIH-NIGMS [SC1GM084776]
NSF CREST [NSF HRD-0932421]

向作者/读者索取更多资源

Protocol

Reagent

摘要

Luminescent cyclometalated platinum(II) complexes, namely [Pt(Thpy)(PPh3)X]n+ (HThpy = 2-(2'-thienyl)pyridine; X = Cl- (1), n = 0; X = CH3CN (2), pyridine (3), n = 1) and [Pt(Thpy)(HThpy)Y]n+ (Y = Cl- (4), n = 0; Y = pyridine (5), n = 1), exhibit structured emission with peak maximum at similar to 556 and 598 nm in degassed acetonitrile and with emission quantum yield and lifetime of up to 0.38 and 26 mu s, respectively. These complexes are efficient photosensitizers of singlet oxygen with yields up to > 90%. Complex 5 exhibited photocytotoxicity towards cancer cells and fluorescence microscopic images of cells incubated with 5 reveal substantial uptake at the nucleus and mitochondria.

作者

我是这篇论文的作者

点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4

评分不足

次要评分

新颖性

-

重要性

-

科学严谨性

-

评价这篇论文

推荐

Article Chemistry, Inorganic & Nuclear

Luminescent 2-phenylbenzothiazole cyclometalated PtII and IrIII complexes with chelating P∧O ligands

David Gomez de Segura, Rebeca Lara, Monica Martinez-Junquera, Elena Lalinde, M. Teresa Moreno

Summary: This study presents the synthesis, structural characterization, and photophysical properties of cyclometalated Pt-II and Ir-III complexes with different functionalized phosphine ligands. The Pt complexes exhibit higher photoluminescence quantum yields in PS films compared to the Ir complexes and the precursor. The higher quantum yield of Pt complexes can be explained by the calculated energy gap between the metal-centered triplet and the ligand-centered triplet/metal-to-ligand charge transfer states.

DALTON TRANSACTIONS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

A Panchromatic Cyclometalated Iridium Dye Based on 2-Thienyl-Perimidine

Paulina Kalle, Marina A. Kiseleva, Sergei Tatarin, Daniil E. Smirnov, Alexander Y. Zakharov, Viktor V. Emets, Andrei Churakov, Stanislav Bezzubov

Summary: The study investigates the structural, electronic, and optical properties of N-unsubstituted and N-methylated 2-(2-thienyl)perimidines using DFT/TDDFT calculations. The results show that these ligands have the potential to be used in the construction of light-harvesting iridium(III) complexes. The resulting iridium(III) dye exhibited panchromatic absorption up to 1000 nm and performed well in dye-sensitized solar cells.

MOLECULES (2022)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Exploring the potential of N?C?N cyclometalated Pt(II) complexes bearing 1,3-di(2-pyridyl)benzene derivatives for imaging and photodynamic therapy

Giulia De Soricellis, Francesco Fagnani, Alessia Colombo, Claudia Dragonetti, Dominique Roberto

Summary: This review summarizes the potential of the family of cyclometalated Pt(II) complexes in bio-imaging and photodynamic therapy, and highlights their advantages and features.

INORGANICA CHIMICA ACTA (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Theoretical investigation on orange-emitting cyclometalated platinum (II) complexes containing organosilyl/organocarbon-substituted 2-(2-thienyl)pyridine ligands

Hadj Mezouar, Houari Brahim

Summary: In this study, a theoretical investigation of the structural, optical, and phosphorescence properties of four cyclometalated Pt(II) complexes containing substituted 2-(2-thienyl)pyridine ligands was conducted using DFT and TD-DFT methods. The results were compared with available experimental data, and the main normal modes involved in phosphorescence bands were analyzed and assigned.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2022)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

The intriguing effect of thiolates as co-ligands in platinum(II) complexes bearing a cyclometalated 1,3-di(2-pyridyl)benzene

Francesco Fagnani, Alessia Colombo, Claudia Dragonetti, Dominique Roberto, Daniele Marinotto

Summary: This study focuses on the substitution of the chlorido ligand in a cyclometalated complex with thioacetate, resulting in a thiolato complex. The photophysical properties of this complex were investigated in different states, revealing changes in phosphorescence spectra, lifetime decays, and quantum yield with increasing complex concentration. The tuning of emission spectra was found to depend on the competition between monomeric and aggregate emissive states.

INORGANICA CHIMICA ACTA (2022)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Luminescent cyclometalated alkynylplatinum(ii) complexes with 1,3-di(pyrimidin-2-yl)benzene ligands: synthesis, electrochemistry, photophysics and computational studies

Mariia Hruzd, Nicolas le Poul, Marie Cordier, Samia Kahlal, Jean-Yves Saillard, Sylvain Achelle, Sebastien Gauthier, Francoise Robin-le Guen

Summary: In this article, a series of cyclometalated platinum(ii) complexes with various tridentate N^C^N-cyclometalated ligands derived from 1,3-bis(pyrimidin-2-yl)benzene were reported. The optical properties of these complexes in solution and solid state were found to be dependent on the substituents. In addition, the DFT calculations correlated well with the experimental data.

DALTON TRANSACTIONS (2022)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

New members of a class of cyclometalated 1,3-di-(2-pyridyl)benzene platinum(II) complexes bearing a tetrazole-thiolate ancillary ligand

Francesco Fagnani, Alessia Colombo, Claudia Dragonetti, Dominique Roberto, Daniele Marinotto

Summary: Substituting the chloride ligand of the cyclometalated complexes [Pt(5-R-dpyb)Cl] (R = methyl, 2-thienyl; dpyb = 1,3-di(2-pyridyl)benzene) with 1-phenyl-1H-tetrazole-5-thiolate leads to the thiolato complexes [Pt(5-R-dpyb)(1-phenyl-1H-tetrazole-5-thiolate)], which have been fully characterized. The photophysical properties of these complexes were determined in degassed dichloromethane solution at room temperature. It was found that the emission color can be controlled by the substituents on the benzene ring, with the introduction of a donor group such as 2-thienyl resulting in a significant red-shift.

INORGANICA CHIMICA ACTA (2023)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Phosphorescent 2-phenylbenzothiazole PtIV bis-cyclometalated complexes with phenanthroline-based ligands

Andrea Corral-Zorzano, David Gomez de Segura, Elena Lalinde, M. Teresa Moreno

Summary: We have investigated a range of dicationic heteroleptic complexes with two cyclometalating 2-phenylbenzothiazole (pbt) groups and a phenanthroline-based ligand. The photophysical and electrochemical properties of these complexes were studied, and different emissive states were observed depending on the medium and excitation wavelength. Theoretical calculations supported these findings and provided insights into the luminescence of these PtIV complexes.

DALTON TRANSACTIONS (2023)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Supramolecular luminescent Pt(ii) tweezers: aggregation studies and O-1(2) production

Guillermo Romo-Islas, Rosa M. Gomila, Antonio Frontera, Laura Rodriguez

Summary: Four series of Pt(ii) tweezer compounds were designed and synthesized to investigate their ability to form luminescent supramolecular assemblies. The compounds have a general chemical structure of (diphos)Pt(N<^>N<^>N), where diphos is a diphosphane that imparts a tweezer structure to the complexes. The four series differ in the substituents of the N<^>N<^>N ligands, which affect their electronic and bulk properties. Spectroscopic analysis and DFT calculations revealed the presence of intra- and intermolecular Pt•••Pt, Pt•••π, and π•••π interactions, leading to aggregates with varying stabilities. The aggregation process was analyzed in both solution and solid state, showing that emission properties are influenced by aggregation, as demonstrated by enhanced phosphorescence emission in the absence of chloride substituents.

INORGANIC CHEMISTRY FRONTIERS (2023)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Luminescent Re(I) scorpionates supported by tris(2-pyridyl)phosphine and its derivatives

Maxim Yu Petyuk, Alexey S. Berezin, Artem L. Gushchin, Irina Yu Bagryanskaya, Andery Yu Baranov, Alexander Artem'ev

Summary: A series of luminescent Re(I) scorpoinates have been successfully synthesized, exhibiting solid state phosphorescence at ambient temperature and thermochromic luminescence upon cooling. The compounds also display interesting spectral and electrochemical properties.

INORGANICA CHIMICA ACTA (2021)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

A new family of luminescent [Pt( pbt)(2)(C6F5)L](n+) (n=1, 0) complexes: synthesis, optical and cytotoxic studies

David Gomez de Segura, Nora Gimenez, David Rincon-Monton, M. Teresa Moreno, Jose G. Pichel, Iciar P. Lopez, Elena Lalinde

Summary: A new family of luminescent heteroleptic pentafluorophenyl-bis(2-phenylbenzothiazolyl) Pt-IV derivatives were designed and their photophysical properties were systematically studied. The cationic complexes 1-3 exhibited remarkable efficacy against lung carcinoma and cervix carcinoma cell lines. The neutral complex 6 showed low cytotoxicity and high photocytotoxicity when irradiated with blue light.

DALTON TRANSACTIONS (2023)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Phosphorescent Tris-cyclometalated Pt(IV) Complexes with Mesoionic N-Heterocyclic Carbene and 2-Arylpyridine Ligands

Angela Vivancos, Delia Bautista, Pablo Gonzalez-Herrero

Summary: This study reports the synthesis, structure, photophysical properties, and electrochemistry of the first series of Pt(IV) tris-chelates bearing cyclometalated aryl-NHC ligands. The complexes exhibit significant photostability, long-lived phosphorescence, and potential application for Pt(IV) emitters with tunable properties.

INORGANIC CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Luminescent halido(aryl) Pt(iv) complexes obtained via oxidative addition of iodobenzene or diaryliodonium salts to bis-cyclometalated Pt(ii) precursors

Juan-Carlos Lopez-Lopez, Delia Bautista, Pablo Gonzalez-Herrero

Summary: The synthesis and photophysical properties of bis-cyclometalated halido(aryl) Pt(iv) complexes are reported. The introduction of aryl ligands through different methods and the comparison of chlorido and fluorido derivatives in terms of emission lifetimes and radiative rate constants are discussed. The study also highlights the role of radical species in the activation of solvents during the oxidative addition reaction.

DALTON TRANSACTIONS (2021)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Luminescent Anionic Cyclometalated Organoplatinum (II) Complexes with Terminal and Bridging Cyanide Ligand: Structural and Photophysical Properties

Mina Sadeghian, David Gomez de Segura, Mohsen Golbon Haghighi, Nasser Safari, Elena Lalinde, M. Teresa Moreno

Summary: This study presents the synthesis and characterization of two series of mononuclear and symmetrical binuclear cycloplatinated(II) complexes. The structures of these complexes were determined by single-crystal X-ray diffraction. One of the complexes showed a high quantum yield of up to 21% in the solid state. Density functional theory (DFT) and time-dependent DFT calculations were used to interpret the absorption and emission properties of these complexes.

INORGANIC CHEMISTRY (2023)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Polymorphism and Mechanochromism in 2-Phenylbenzothiazole Cyclometalated PtII Complexes with Chelating N⊥O Ligands

David Gomez de Segura, Elena Lalinde, M. Teresa Moreno

Summary: New cyclometalated PtII complexes with different picolinate ligands were synthesized, and the solid-state packing and photophysical properties were modulated through donor-acceptor H-bonding interactions and stacking interactions. Theoretical calculations and experimental studies revealed the influence of metal-metal contacts and chelate stacking on the charge transfer character.

INORGANIC CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands: Thiol Switch-on Fluorescent Probes and Anti-Cancer Agents

Taotao Zou, Ching Tung Lum, Stephen Sin-Yin Chui, Chi-Ming Che

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

A gold(III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells

Ching Tung Lum, Alice Sze-Tsai Wong, Marie C. M. Lin, Chi-Ming Che, Raymond Wai-Yin Sun

CHEMICAL COMMUNICATIONS (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Luminescent organoplatinum(II) complexes containing bis(N-heterocyclic carbene) ligands selectively target the endoplasmic reticulum and induce potent photo-toxicity

Taotao Zou, Chun-Nam Lok, Yi Man Eva Fung, Chi-Ming Che

CHEMICAL COMMUNICATIONS (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

[RuIV(F20-TPP)Cl2] efficiently catalysed inter- and intra-molecular nitrene insertion into sp3 C-H bonds of hydrocarbons using phosphoryl azides as nitrene sources

Wenbo Xiao, Jinhu Wei, Cong-Ying Zhou, Chi-Ming Che

CHEMICAL COMMUNICATIONS (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Deubiquitinases as potential anti-cancer targets for gold(III) complexes

Jing-Jing Zhang, Kwan-Ming Ng, Chun-Nam Lok, Raymond Wai-Yin Sun, Chi-Ming Che

CHEMICAL COMMUNICATIONS (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nonheme Iron-Mediated Amination of C(sp3)-H Bonds. Quinquepyridine-Supported Iron-Imide/Nitrene Intermediates by Experimental Studies and DFT Calculations

Yungen Liu, Xiangguo Guan, Ella Lai-Ming Wong, Peng Liu, Jie-Sheng Huang, Chi-Ming Che

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

添加到收藏夹

Article Optics

Efficient red organic electroluminescent devices by doping platinum(II) Schiff base emitter into two host materials with stepwise energy levels

Liang Zhou, Chi-Chung Kwok, Gang Cheng, Hongjie Zhang, Chi-Ming Che

OPTICS LETTERS (2013)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Luminescent Pincer-Type Cyclometalated Platinum(II) Complexes with Auxiliary Isocyanide Ligands: Phase-Transfer Preparation, Solvatomorphism, and Self-Aggregation

Yong Chen, Wei Lu, Chi-Ming Che

ORGANOMETALLICS (2013)

添加到收藏夹

Review Multidisciplinary Sciences

Light-induced catalytic and cytotoxic properties of phosphorescent transition metal compounds with a d8 electronic configuration

Wai-Pong To, Taotao Zou, Raymond Wai-Yin Sun, Chi-Ming Che

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

An ytterbium(III) porphyrin induces endoplasmic reticulum stress and apoptosis in cancer cells: cytotoxicity and transcriptomics studies

Wai-Lun Kwong, Raymond Wai-Yin Sun, Chun-Nam Lok, Fung-Ming Siu, Suk-Yu Wong, Kam-Hung Low, Chi-Ming Che

CHEMICAL SCIENCE (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Light-emitting platinum(II) complexes supported by tetradentate dianionic bis(N-heterocyclic carbene) ligands: towards robust blue electrophosphors

Kai Li, Gang Cheng, Chensheng Ma, Xiangguo Guan, Wai-Ming Kwok, Yong Chen, Wei Lu, Chi-Ming Che

CHEMICAL SCIENCE (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

A dinuclear cyclometalated gold(III)-phosphine complex targeting thioredoxin reductase inhibits hepatocellular carcinoma in vivo

Raymond Wai-Yin Sun, Chun-Nam Lok, Tommy Tsz-Him Fong, Carrie Ka-Lei Li, Zhen Fan Yang, Taotao Zou, Annie Fung-Ming Siu, Chi-Ming Che

CHEMICAL SCIENCE (2013)

添加到收藏夹

Article Chemistry, Physical

Enantioselective Intramolecular Carbene C-H Insertion Catalyzed by a Chiral Iridium(III) Complex of D4-Symmetric Porphyrin Ligand

Jing-Cui Wang, Yan Zhang, Zhen-Jiang Xu, Vanessa Kar-Yan Lo, Chi-Ming Che

ACS CATALYSIS (2013)

添加到收藏夹

Article Infectious Diseases

A Universal LC-MS/MS Method for Simultaneous Detection of Antibiotic Residues in Animal and Environmental Samples

Chak-Lun Chan, Hogan Kok-Fung Wai, Peng Wu, Siu-Wai Lai, Olivia Sinn-Kay Chan, Hein M. Tun

Summary: This study presents a methodology for simultaneous extraction and detection of antibiotic residues in animal and environmental samples. It can qualitatively detect 30 different antibiotics and has the potential for quantification of antibiotic residues.

ANTIBIOTICS-BASEL (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Metal-coding assisted serological multi-omics profiling deciphers the role of selenium in COVID-19 immunity

Ying Zhou, Shuofeng Yuan, Fan Xiao, Hongyan Li, Ziwei Ye, Tianfan Cheng, Cuiting Luo, Kaiming Tang, Jianpiao Cai, Jianwen Situ, Siddharth Sridhar, Wing-Ming Chu, Anthony Raymond Tam, Hin Chu, Chi-Ming Che, Lijian Jin, Ivan Fan-Ngai Hung, Liwei Lu, Jasper Fuk-Woo Chan, Hongzhe Sun

Summary: Understanding how host metal(loid)s regulate immune response is crucial for understanding the mechanism of infectious diseases. This study established a metal-coding system to analyze the links between metallome and COVID-19 pathogenesis and immunity. COVID-19 patients showed distinct metallome features compared to non-infected individuals, which could serve as biomarkers for disease diagnosis. Selenium was found to be strongly associated with interleukin-10 (IL-10), and selenium supplementation enhanced IL-10 expression in B cells while reducing proinflammatory cytokines in B and CD4+ T cells. Additionally, selenium supplementation alleviated lung damage in SARS-CoV-2-infected mice.

CHEMICAL SCIENCE (2023)

添加到收藏夹

暂无数据

© Peeref 2019-2024. All rights reserved.