Article
Chemistry, Multidisciplinary
Shohei Yamashita, Tatsuya Sudo, Hidehiro Kamiya, Yohei Okada
Summary: This study is important for understanding the effects of surface ligands on the colloidal stability of nanoparticles and proposes a method that can be applied to various surface ligands to maximize the colloidal stability of nanoparticles.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Physical
Congcong Liu, Haijun Su, Yu Pu, Min Guo, Peng Zhai, Zhike Liu, Zhuo Zhang
Summary: The addition of difluoromethyl phosphonic acid diethyl ester (2F-PAE) successfully alleviates the deep- and shallow-level defects in perovskite solar cells, resulting in improved performance and stability.
Article
Chemistry, Multidisciplinary
Sourav Biswas, Anish Kumar Das, Akashdeep Nath, Souradip Paul, M. Suheshkumar Singh, Sukhendu Mandal
Summary: This study investigates a newly synthesized silver cluster assembled material and demonstrates the correlation between its structure and properties, showing how a multifunctional surface protecting ligand is strategically attached to enhance solubility, structural stability, and charge transfer mechanism. The material exhibits high structural stability, sustainable photoresponsive character, and unprecedented water solubility, making it suitable for biomedical imaging applications. The material's ability to mimic blood vessels at a depth of approximately 3 mm inside chicken breast tissue was confirmed by measured photoacoustic signal strength.
Article
Green & Sustainable Science & Technology
Noufal Komby Abdulla, Sharf Ilahi Siddiqui, Bushra Fatima, Razia Sultana, Nusrat Tara, Athar Adil Hashmi, Razi Ahmad, Mohd Mohsin, Ranjeet Kumar Nirala, Nguyen Thuy Linh, Quang-Vu Bach, Saif Ali Chaudhry
Summary: The synthesis, characterization, adsorption, and antibacterial activities of a silver-based hybrid nanocomposite composed of silver, zirconium oxides, and an organic framework derived from Psidium guajava leaves were reported. The composite showed efficient adsorption of methylene blue dye from water, significant reusability, and antibacterial activity against Escherichia coli and Staphylococcus aureus.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Materials Science, Multidisciplinary
K. Karthikeyan, V. Mariappan, P. Kalidoss, R. Anish, P. Sarafoji, Janke Venkatanageswara Reddy, Tapas Kumar Satpathy
Summary: The capric-myristic acid binary eutectic mixture was prepared as a phase change material for building applications. Hybrid-nanocomposite PCMs were formed by adding silver-antimony tin oxide and silver-graphane nanoplatelets to the mixture. The HNCPCMs showed improved thermal conductivity and stability, making it a promising material for buildings.
Article
Engineering, Chemical
Nikos Kyriakou, Elmar Boorsma, Gert-Jan Aardema, Guido Ritsema van Eck, Martin Drobek, Sissi de Beer, Arian Nijmeijer, Louis Winnubst, Marie-Alix Pizzoccaro-Zilamy
Summary: Grafting oligomers into ceramic membranes represents an attractive strategy for wastewater treatment. However, achieving a homogeneous surface modification and high grafting yields is challenging with current approaches. In this study, a novel synthesis method using concentrated PEG organophosphonic acid oligomer solution was presented, which resulted in the formation of robust PEG-based membranes with controlled surface properties. The influence of solvent polarity on the conformation of the grafted PEG brush was observed and studied for the first time by molecular dynamic simulations. The as-prepared PEG-brush/ceramic membranes showed high efficiency in separating small organic dyes.
JOURNAL OF MEMBRANE SCIENCE
(2023)
Article
Chemistry, Inorganic & Nuclear
Gang-Mei Li, Fei Xu, Song-De Han, Jie Pan, Guo-Ming Wang
Summary: Hybrid photochromic materials with specific photoresponsive functionality have various applications. In this study, a new electron acceptor was introduced and a hybrid metal phosphonate with fascinating photoresponsive functionality was synthesized.
INORGANIC CHEMISTRY
(2022)
Article
Electrochemistry
Xinlin Shi, Xiaohui Chen, Wanying Zuo, Luyin Lin, Wenhuang Xiao, Haipeng Yang
Summary: In this study, an amperometric sarcosine biosensor was developed using an organic-inorganic hybrid mesoporous tungsten phosphonate material. The biosensor exhibited both anti-interference and electrocatalytic functions, with a wide linear detection range and good ability to exclude interference signals from common substances.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Environmental Sciences
Aline M. Z. de Medeiros, Latif U. Khan, Gabriela H. da Silva, Carlos A. Ospina, Oswaldo L. Alves, Vera Lucia de Castro, Diego Stefani T. Martinez
Summary: This study investigated the toxicity of graphene oxide-silver nanoparticle hybrid material in zebrafish embryos, considering factors such as natural organic matter and chorion membrane. The results demonstrated a dose-response acute toxicity of the nanohybrid, with significant impacts from the removal of chorion and presence of NOM. Raman spectroscopy confirmed the ingestion of graphene oxide by embryos, while silver nanoparticles played a role in mitigating toxicity effects. Understanding the influence of chorion membranes and NOM is crucial for standardizing testing in zebrafish embryo toxicity assessments.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Materials Science, Multidisciplinary
Xiaofeng Hao, Zhen Li, Min Xiao, Zhiheng Huang, Dongmei Han, Sheng Huang, Wei Liu, Shuanjin Wang, Yuezhong Meng
Summary: The challenge of optimizing and regulating the distribution of phosphoric acid in matrix and improving the performance and lifetime of high temperature proton exchange membrane (HT-PEMs) fuel cells is addressed by preparing and investigating bifunctional copolymers with tethered phosphonic acid (t-PA) and intrinsic tertiary amine base groups. The unique architecture of the copolymers enables rapid proton transport through both hydrogen bond networks and proton channels. The bifunctional copolymers with lower PA uptake levels demonstrate excellent proton conductivity, power density, and voltage stability, achieving a top leading result in the literature. The study highlights the importance of intermolecular acid-base-pairs in enhancing proton conductivity without sacrificing chemical stability or mechanical properties of HT-PEMs.
ENERGY & ENVIRONMENTAL MATERIALS
(2023)
Article
Materials Science, Textiles
Tiandong Huang, Fang Xu, Peiyi Zhao, Peng Wang, Fengxiu Zhang, Guangxian Zhang
Summary: A novel urea tetramethylene diphosphate dimethyl ammonium diphosphate (UTDDAD) flame retardant has been successfully synthesized, showing excellent flame retardancy and durability in cotton fabric while maintaining approximately 70% of the original tensile strength. Introduction of phosphonate groups in flame retardants proves to be an effective strategy for increasing the durability of flame retardant cotton products.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Chemistry, Organic
Nikoletta Harsagi, Csilla Bertha, Nora Zsuzsa Kiss, Reka Henyecz, Petra Regina Varga, Peter Abranyi-Balogh, Laszlo Drahos, Gyorgy Keglevich
Summary: In the microwave-assisted alcoholysis of dialkyl phenylphosphonates in the presence of suitable ionic liquids, it was found that the phosphonate function inevitably underwent fission to ester-acid or diacid moieties. Additionally, the presence of [emim][HSO4] led to a reaction with selectivities of 66% for phosphonic esteracid and 97% for diacid. The ester-acids produced by this new protocol may serve as valuable intermediates.
CURRENT ORGANIC CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Dajana Mikic, Helena Otmacic Curkovic, Saman Hosseinpour
Summary: The corrosion resistance of bronze surfaces was evaluated by modifying them with films of methyl, carboxyl, and amino terminated phosphonic acids. The impact of the terminal group and film thickness on corrosion resistance was assessed. It was found that films formed in 1 mM phosphonic acid solutions provided better corrosion protection, while carboxyl terminated phosphonic acid films exhibited the least protective film on bronze.
Article
Multidisciplinary Sciences
Joo Sung Kim, Jung-Min Heo, Gyeong-Su Park, Seung-Je Woo, Changsoon Cho, Hyung Joong Yun, Dong-Hyeok Kim, Jinwoo Park, Seung-Chul Lee, Sang-Hwan Park, Eojin Yoon, Neil C. Greenham, Tae-Woo Lee
Summary: This study reports the development of ultra-bright, efficient, and stable light-emitting diodes (PeLEDs) made of core/shell perovskite nanocrystals. The nanocrystals, obtained through in situ reaction of benzylphosphonic acid with polycrystalline perovskite films, demonstrate strong carrier confinement and maintain good charge-transport properties.
Article
Biochemistry & Molecular Biology
Guillem Ferreres, Silvia Perez-Rafael, Juan Torrent-Burgues, Tzanko Tzanov
Summary: Silver nanoparticles (Ag NPs) are considered promising antimicrobial materials to combat antibiotic resistance. This study found that the molecular weight of hyaluronic acid played a crucial role in the morphology, size, and antibacterial activity of the Ag NPs. Higher molecular weight polymers showed greater interaction with bacteria and better bactericidal effects, while lower molecular weight polymers had reduced antimicrobial efficacy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biotechnology & Applied Microbiology
Yann Thierry Le Guen, Tony Le Gall, Patrick Midoux, Philippe Guegan, Serge Braun, Tristan Montier
JOURNAL OF GENE MEDICINE
(2020)
Article
Biochemistry & Molecular Biology
Bazoly Rasolonjatovo, Nicolas Illy, Veronique Bennevault, Jerome Mathe, Patrick Midoux, Tony Le Gall, Thomas Haudebourg, Tristan Montier, Pierre Lehn, Bruno Pitard, Herve Cheradame, Cecile Huin, Philippe Guegan
MACROMOLECULAR BIOSCIENCE
(2020)
Article
Optics
D. Markina, E. Yu Tiguntseva, A. P. Pushkarev, M. A. Samsonov, M. Vengris, B. Munkhbat, T. Shegai, G. B. Hix, A. A. Zakhidov, S. Makarov
JOURNAL OF LUMINESCENCE
(2020)
Review
Pharmacology & Pharmacy
Rosy Ghanem, Veronique Laurent, Philippe Roquefort, Tanguy Haute, Sophie Ramel, Tony Le Gall, Thierry Aubry, Tristan Montier
Summary: The respiratory epithelium is susceptible to diseases like cystic fibrosis, which impact airway function. Artificial mucus models play a crucial role in evaluating gene transfer systems' effectiveness in reaching the epithelium.
Article
Medicine, General & Internal
Y. T. Le Guen, T. Le Gall, V Laurent, F. D'Arbonneau, S. Braun, T. Montier
Summary: Duchenne muscular dystrophy is a common type of muscular dystrophy caused by mutations in the dystrophin gene, leading to a lower life span and quality of life compared to the general population. New therapeutic approaches are being investigated to provide new perspectives and hope for the care of this severe disease.
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE
(2021)
Article
Medicine, Research & Experimental
Yann T. Le Guen, Chantal Pichon, Philippe Guegan, Kevin Pluchon, Tanguy Haute, Sandrine Quemener, Juliette Ropars, Patrick Midoux, Tony Le Gall, Tristan Montier
Summary: The study focuses on the enhanced nuclear import of plasmid DNA carrying 3NF sequences through interaction with NF-kappa B. Results show modest to substantial advantages for 3NF-equipped pDNA in both in vitro and in vivo gene transfer applications, emphasizing the potential of optimized nuclear import for efficient non-viral gene transfer.
MOLECULAR THERAPY-NUCLEIC ACIDS
(2021)
Article
Cell Biology
Rosy Ghanem, Philippe Roquefort, Sophie Ramel, Veronique Laurent, Tanguy Haute, Tony Le Gall, Thierry Aubry, Tristan Montier
Summary: The mucus in CF patients' airways is a yield stress fluid with unique rheological properties. Rheological analyses can provide biophysical markers for disease management. Treatment with rhDNAse appears to lower the apparent yield stress of CF sputum, which could be a predictive biomarker for prognosis and aid in the development of new mucolytic agents.
Article
Pharmacology & Pharmacy
Tony Le Gall, Mathieu Berchel, Lee Davies, Angelique Mottais, Rosy Ghanem, Alain Fautrel, Deborah Gill, Steve Hyde, Pierre Lehn, Jean-Marie Lehn, Loic Lemiegre, Thierry Benvegnu, Paul-Alain Jaffres, Bruno Pitard, Tristan Montier
Summary: Aerosol lung gene therapy using non-viral delivery systems shows promise as a therapeutic strategy for chronic respiratory diseases. This study demonstrates that lipidic aminoglycoside derivative-based formulations possess efficient lung transfection activity following aerosol delivery, suggesting their potential as alternatives to GL67A.
Review
Pharmacology & Pharmacy
Raphaelle Youf, Max Mueller, Ali Balasini, Franck Thetiot, Mareike Mueller, Alize Hascoet, Ulrich Jonas, Holger Schoenherr, Gilles Lemercier, Tristan Montier, Tony Le Gall
Summary: Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern therapeutics, with the ability to treat localized infections by combining various photosensitizers and other antimicrobial treatments. This review summarizes the latest advances in aPDT applications and discusses developments in photochemistry, photophysics, and carrier systems.
Article
Engineering, Biomedical
Zhiyuan Jia, Mareike Mueller, Tony Le Gall, Martijn Riool, Max Mueller, Sebastian A. J. Zaat, Tristan Montier, Holger Schoenherr
Summary: This study developed color-encoded chitosan hydrogels for rapid and sensitive detection of bacterial enzymes and differentiating bacterial strains. The hydrogels with three different colorimetric enzyme substrates can detect and differentiate alpha-glucosidase, beta-galactosidase, and beta-glucuronidase, showing potential for point-of-care microbiological diagnostics in food safety and medical settings.
BIOACTIVE MATERIALS
(2021)
Article
Immunology
Jiwar Al-Zawity, Faria Afzal, Aysha Awan, Daniela Nordhoff, Alexander Kleimann, Daniel Wesner, Tristan Montier, Tony Le Gall, Mareike Muller
Summary: This study investigates the influence of the steroid sex hormone estradiol (E-2) on biofilm formation of Pseudomonas aeruginosa in cystic fibrosis (CF) patients. The results show that E-2 treatment can increase the attached biofilm mass, remodel the biofilm ultrastructure, and potentially modulate the QS signaling in the biofilm.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Pharmacology & Pharmacy
Raphaelle Youf, Adeel Nasir, Mareike Mueller, Franck Thetiot, Tanguy Haute, Rosy Ghanem, Ulrich Jonas, Holger Schoenherr, Gilles Lemercier, Tristan Montier, Tony Le Gall
Summary: Antimicrobial photodynamic therapy (aPDT) is a treatment method that relies on various parameters. In this study, the application of Ruthenium(II) polypyridyl ([Ru(II)]) complexes in the airways of Cystic Fibrosis (CF) patients was investigated, and the influence of different parameters on their properties was studied. The results provide significant evidence for the clinical relevance of [Ru(II)]-based aPDT in CF lung airways.
Article
Pharmacology & Pharmacy
Rosy Ghanem, Mathieu Berchel, Tanguy Haute, Xavier Buin, Veronique Laurent, Raphaelle Youf, Amal Bouraoui, Tony Le Gall, Paul-Alain Jaffres, Tristan Montier
Summary: In cystic fibrosis gene therapy, aerosolization of genetic materials is the most relevant delivery strategy to reach the airway epithelium. This study compared the efficiency of gene delivery by aerosolization of two formulations: BSV163-based and b-PEI-based. Results showed that the DOPE ratio of the BSV163-based formulations influenced their ability to mediate high transfection efficacies.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Chemistry, Analytical
Hamid Pouran, Rosario Perez Colodrero, Shuang Wu, Gary Hix, Julia Zakharova, Hao Zhang
ANALYTICAL METHODS
(2020)
Article
Chemistry, Organic
Amal Bouraoui, Rosy Ghanem, Mathieu Berchel, Laure Deschamps, Veronique Vie, Gilles Paboeuf, Tony Le Gall, Tristan Montier, Paul-Alain Jaffres
ORGANIC & BIOMOLECULAR CHEMISTRY
(2020)
