Organization, control and function of extrasynaptic NMDA receptors

d-Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain

(2014) Darrick T. Balu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Prefrontal Deficits in a Murine Model Overexpressing the Down Syndrome Candidate Gene Dyrk1a

(2014) A. Thomazeau et al.   JOURNAL OF NEUROSCIENCE

Involvement of the GluN2A and GluN2B Subunits in Synaptic and Extrasynaptic N -methyl-d-aspartate Receptor Function and Neuronal Excitotoxicity

(2013) Xianju Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Presynaptic NMDA Receptor Mechanisms for Enhancing Spontaneous Neurotransmitter Release

(2013) P. A. Kunz et al.   JOURNAL OF NEUROSCIENCE

Extrasynaptic Targeting of NMDA Receptors Following D1 Dopamine Receptor Activation and Cocaine Self-Administration

(2013) P. I. Ortinski et al.   JOURNAL OF NEUROSCIENCE

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

A  induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

(2013) M. Talantova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NMDA receptor-mediated excitotoxicity depends on the coactivation of synaptic and extrasynaptic receptors

(2013) X Zhou et al.   Cell Death & Disease

Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level

(2013) Yan Li et al.   Nature Communications

High glutamate permeability and distal localization of Best1 channel in CA1 hippocampal astrocyte

(2013) Hyungju Park et al.   Molecular Brain

Activation of extrasynaptic NMDA receptors induces LTD in rat hippocampal CA1 neurons

(2012) Dan-dan Liu et al.   BRAIN RESEARCH BULLETIN

TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation

(2012) Dong Ho Woo et al.   CELL

Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists

(2012) Thomas Papouin et al.   CELL

Tonic NMDA receptor-mediated current in prefrontal cortical pyramidal cells and fast-spiking interneurons

(2012) Nadezhda V. Povysheva et al.   JOURNAL OF NEUROPHYSIOLOGY

Synaptic NMDA Receptors Mediate Hypoxic Excitotoxic Death

(2012) C. M. Wroge et al.   JOURNAL OF NEUROSCIENCE

The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults

(2012) Marc-André Martel et al.   NEURON

Backpropagating Action Potentials Enable Detection of Extrasynaptic Glutamate by NMDA Receptors

(2012) Yu-Wei Wu et al.   Cell Reports

Protease Activated Receptor 1-induced glutamate release in cultured astrocytes is mediated by Bestrophin-1 channel but not by vesicular exocytosis

(2012) Soo-Jin Oh et al.   Molecular Brain

Extrasynaptic Glutamate Receptor Activation as Cellular Bases for Dynamic Range Compression in Pyramidal Neurons

(2012) Katerina D. Oikonomou et al.   Frontiers in Physiology

Immunogold Detection of L-glutamate and D-serine in Small Synaptic-Like Microvesicles in Adult Hippocampal Astrocytes

(2011) L.H. Bergersen et al.   CEREBRAL CORTEX

Molecular basis of NMDA receptor functional diversity

(2011) Pierre Paoletti   EUROPEAN JOURNAL OF NEUROSCIENCE

Alterations in protein metabolism and amino acid concentrations in rats fed by a high-protein (casein-enriched) diet – Effect of starvation

(2011) Milan Holecek et al.   FOOD AND CHEMICAL TOXICOLOGY

State-dependent changes in astrocyte regulation of extrasynaptic NMDA receptor signalling in neurosecretory neurons

(2011) Tiffany M. Fleming et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function

(2011) Clare M. Gladding et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Levels of d-serine in the brain and peripheral organs of serine racemase (Srr) knock-out mice

(2011) Mao Horio et al.   NEUROCHEMISTRY INTERNATIONAL

Bidirectional Neuron–Glia Interactions Triggered by Deficiency of Glutamate Uptake at Spinal Sensory Synapses

(2010) Hui Nie et al.   JOURNAL OF NEUROPHYSIOLOGY

Activation of Extrasynaptic, But Not Synaptic, NMDA Receptors Modifies Amyloid Precursor Protein Expression Pattern and Increases Amyloid-  Production

(2010) K. Bordji et al.   JOURNAL OF NEUROSCIENCE

Memantine Preferentially Blocks Extrasynaptic over Synaptic NMDA Receptor Currents in Hippocampal Autapses

(2010) P. Xia et al.   JOURNAL OF NEUROSCIENCE

Glutamate-mediated astrocyte-to-neuron signalling in the rat dorsal horn

(2010) Rita Bardoni et al.   JOURNAL OF PHYSIOLOGY-LONDON

Alterations in the hippocampal glycinergic system in an animal model of posttraumatic stress disorder

(2010) Shigeto Yamamoto et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Long-term potentiation depends on release of d-serine from astrocytes

(2010) Christian Henneberger et al.   NATURE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Do astrocytes really exocytose neurotransmitters?

(2010) Nicola B. Hamilton et al.   NATURE REVIEWS NEUROSCIENCE

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Organization of NMDA receptors at extrasynaptic locations

(2010) R.S. Petralia et al.   NEUROSCIENCE

Glycine and glycine receptor signaling in hippocampal neurons: Diversity, function and regulation

(2010) Tian-Le Xu et al.   PROGRESS IN NEUROBIOLOGY

NMDA- and  -Amyloid1-42-Induced Neurotoxicity Is Attenuated in Serine Racemase Knock-Out Mice

(2009) R. Inoue et al.   JOURNAL OF NEUROSCIENCE

Coagonist Release Modulates NMDA Receptor Subtype Contributions at Synaptic Inputs to Retinal Ganglion Cells

(2009) T. L. Kalbaugh et al.   JOURNAL OF NEUROSCIENCE

Extrasynaptic NMDA Receptors Couple Preferentially to Excitotoxicity via Calpain-Mediated Cleavage of STEP

(2009) J. Xu et al.   JOURNAL OF NEUROSCIENCE

Characteristics of glycine transport across the inner blood–retinal barrier

(2009) Masashi Okamoto et al.   NEUROCHEMISTRY INTERNATIONAL

Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors

(2008) F. Léveillé et al.   FASEB JOURNAL

Two Forms of Astrocyte Calcium Excitability Have Distinct Effects on NMDA Receptor-Mediated Slow Inward Currents in Pyramidal Neurons

(2008) E. Shigetomi et al.   JOURNAL OF NEUROSCIENCE

Which GABAA Receptor Subunits Are Necessary for Tonic Inhibition in the Hippocampus?

(2008) J. Glykys et al.   JOURNAL OF NEUROSCIENCE

Surface trafficking of N-methyl-d-aspartate receptors: Physiological and pathological perspectives

(2008) L. Groc et al.   NEUROSCIENCE

Morphological evidence for vesicular glutamate release from astrocytes

(2008) L.H. Bergersen et al.   NEUROSCIENCE

Recruiting Extrasynaptic NMDA Receptors Augments Synaptic Signaling

(2007) Alexander Z. Harris et al.   JOURNAL OF NEUROPHYSIOLOGY