期刊
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
卷 369, 期 1954, 页码 4331-4351出版社
ROYAL SOC
DOI: 10.1098/rsta.2011.0139
关键词
benchmark; electrophysiology; cardiac; modelling; verification
资金
- Newton Institute
- UK Biotechnology and Biological Sciences Research Council
- Wellcome Trust
- UK Engineering and Physical Sciences Research Council [EP/F059361/1, EP/F043929/1, EP/G007527/1, EP/D048400/1]
- Medical Research Council
- Richard A. and Nora Eccles Fund for Cardiovascular Research
- Nora Eccles Treadwell Foundation
- British Heart Foundation [PG/08/019/24600]
- European Commission [22449, 224381]
- UK Medical Research Council
- Plan Nacional de Investigacion Cientifica
- Desarrollo e Innovacion Tecnologica del Ministerio de Ciencia e Innovacion, Spain [TEC2008-0290]
- National Science Foundation [0824399, 0926190, 1028261]
- Research Council of Norway
- Austria Science Fund [F3210-N18]
- National Institute of Health [1RO1 HL 10119601]
- EPSRC [EP/F043929/1, EP/F059361/1, EP/D048400/1, EP/G007527/1] Funding Source: UKRI
- MRC [G0701776] Funding Source: UKRI
- Austrian Science Fund (FWF) [F 3201] Funding Source: researchfish
- Engineering and Physical Sciences Research Council [EP/F043929/1, EP/H019898/1, EP/D048400/1, EP/F059361/1, EP/G007527/1] Funding Source: researchfish
- Medical Research Council [G0701776] Funding Source: researchfish
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [0824399] Funding Source: National Science Foundation
- Directorate For Engineering
- Div Of Civil, Mechanical, & Manufact Inn [1028261] Funding Source: National Science Foundation
- Division Of Computer and Network Systems
- Direct For Computer & Info Scie & Enginr [0926190] Funding Source: National Science Foundation
Ongoing developments in cardiac modelling have resulted, in particular, in the development of advanced and increasingly complex computational frameworks for simulating cardiac tissue electrophysiology. The goal of these simulations is often to represent the detailed physiology and pathologies of the heart using codes that exploit the computational potential of high-performance computing architectures. These developments have rapidly progressed the simulation capacity of cardiac virtual physiological human style models; however, they have also made it increasingly challenging to verify that a given code provides a faithful representation of the purported governing equations and corresponding solution techniques. This study provides the first cardiac tissue electrophysiology simulation benchmark to allow these codes to be verified. The benchmark was successfully evaluated on 11 simulation platforms to generate a consensus gold-standard converged solution. The benchmark definition in combination with the gold-standard solution can now be used to verify new simulation codes and numerical methods in the future.
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