Article
Food Science & Technology
Sarah Auguste, Bing Yan, Maolin Guo
Summary: Polyphenols found in tea can induce mitophagy in human fibroblast cells, and the induction of mitophagy may play an important role in the anti-aging mechanism of tea.
Article
Food Science & Technology
Qingping Ma, Laichao Song, Zhanhai Niu, Ziyuan Qiu, Haiwei Sun, Zhihong Ren, Huanhuan Wu, Yu Wang, Huiling Mei, Xinghui Li, Zhaotang Ding
Summary: This study elucidated the mechanism of how pea-tea intercropping affects tea quality through transcriptome and metabolome analyses. The results showed that pea intercropping led to a decrease in catechins and an increase in amino acids in tea leaves. Additionally, there were significant differences in gene expression related to amino acid metabolism and flavonoid biosynthesis.
Article
Plant Sciences
YunFei Li, YiQin Chen, JiaHao Chen, ChengWen Shen
Summary: In the context of global climate change, understanding the stress response of tea plants and its underlying mechanisms is crucial. Over the past two decades, research in this field has thrived, highlighting the importance of flavonoid metabolites in tea plant stress response and quality maintenance.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Food Science & Technology
Ronimara A. Santos, Emmanuele D. S. Andrade, Mariana Monteiro, Eliane Fialho, Jerson L. Silva, Julio B. Daleprane, Danielly C. Ferraz da Costa
Summary: This study demonstrates the potential efficacy of green tea extract in chemoprevention of breast cancer, showing selective effects on breast tumor cells without cytotoxicity on non-tumoral cells. The mechanism involves regulation of p53 and p21 gene expression to induce apoptosis and inhibit cell migration in breast tumor cells.
Article
Plant Sciences
Golam Jalal Ahammed, Xin Li
Summary: This article discusses the health benefits of tea and the role of plant hormones in improving the levels of beneficial compounds in tea. The biosynthesis of polyphenols, catechins, theanine, and caffeine in tea is strongly influenced by environmental conditions. Optimal hormone combinations may help maintain tea quality, benefiting both consumers and producers.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2022)
Article
Food Science & Technology
Zihao Wang, Bingsong Ma, Cunqiang Ma, Chengqin Zheng, Binxing Zhou, Guiyi Guo, Tao Xia
Summary: Through metabolomics analysis, significant differences were found in Xinyang Maojian teas from different production places, which could be identified through 63 differential metabolites.
JOURNAL OF FOOD SCIENCE
(2021)
Review
Chemistry, Multidisciplinary
Iyyakkannu Sivanesan, Judy Gopal, Manikandan Muthu, Sechul Chun, Jae-Wook Oh
Summary: Matcha, a traditional Japanese tea, is known for its high levels of bioactive components and polyphenols. Despite being less researched compared to green tea, the future potential of matcha relies on increased scientific awareness and research attention.
APPLIED SCIENCES-BASEL
(2021)
Review
Food Science & Technology
Ramkumar Samynathan, Muthu Thiruvengadam, Shivraj Hariram Nile, Mohammad Ali Shariati, Maksim Rebezov, Raghvendra Kumar Mishra, Baskar Venkidasamy, Sureshkumar Periyasamy, Ill-Min Chung, Mirian Pateiro, Jose M. Lorenzo
Summary: Tea, made from the shoots of Camellia sinensis (L.) O. Kuntze, is the most commonly consumed nonalcoholic drink worldwide. The metabolites in tea have a wide range of therapeutic applications, particularly their antioxidant and disease-fighting properties in synergy with synthetic drugs. The bioactive flavonoids in tea also contribute to health benefits.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Jinjin Xue, Panpan Liu, Lin Feng, Lin Zheng, Anhui Gui, Xueping Wang, Shengpeng Wang, Fei Ye, Jing Teng, Shiwei Gao, Pengcheng Zheng
Summary: The effects of different fixation methods on the chemical characteristics of green tea were studied. The results showed that high-temperature fixation induced changes in protein oxidation, degradation of flavonoid glycosides, and epimerization of catechins, leading to the accumulation of amino acids, peptides, flavonoids, and catechins, which influenced the taste of green tea.
Article
Nutrition & Dietetics
Guojun Wu, Anna B. Liu, Yang Xu, Ying Wang, Liping Zhao, Yukihiko Hara, Yan Y. Lam, Chung S. Yang
Summary: Green tea extracts and tea catechins are effective in preventing or alleviating diabetes, with powder form green tea leaves (GTP) potentially less effective than green tea extracts (GTE). The study found that 1% GTE was beneficial in preventing diabetes development, while 1% GTP may lead to increased food intake and elevated blood glucose. Furthermore, adjustments in gut microbiota were also associated with the progression of diabetes.
Review
Biochemistry & Molecular Biology
Joanna Kochman, Karolina Jakubczyk, Justyna Antoniewicz, Honorata Mruk, Katarzyna Janda
Summary: Matcha, a type of powdered green tea grown in a traditional way in Japan, is considered the highest quality tea due to its unique chemical composition and prized flavor. Its health-promoting properties, attributed to the high content of antioxidant and anti-inflammatory substances, may have a positive effect on both physical and mental health. Studies confirm the high antioxidant potential of matcha, originating from its considerable content of catechins, beneficial for human health.
Article
Medicine, Research & Experimental
Yasemin Acar, Duygu Agagunduz, Paola De Cicco, Raffaele Capasso
Summary: This paper provides a literature review on the neurological roles of flavonoids, one of the most abundant phytochemical families, in Parkinson's disease (PD). Flavonoids have been shown to have beneficial effects on PD, such as protecting dopaminergic neurons, improving motor and cognitive abilities, regulating signaling pathways, and modulating oxidative stress and neuroinflammation. In addition, flavonoids can also promote the growth of beneficial strains and reduce pathogenic strains by changing the composition of bacteria in gut microbiota.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Medicine, General & Internal
Abby Keller, Taylor C. Wallace
Summary: This review suggests that consistently consuming 2 cups of unsweet tea per day can potentially decrease the risk and progression of cardiovascular disease. It also indicates that consuming tea as a beverage does not appear to be harmful to health, with potential benefits outweighing risks. Future large-scale clinical intervention studies are needed to confirm the effects observed in observational studies and provide better mechanistic insight.
ANNALS OF MEDICINE
(2021)
Review
Chemistry, Medicinal
Pawel Bakun, Dariusz T. Mlynarczyk, Tomasz Koczorowski, Magdalena Cerbin-Koczorowska, Ludwika Piwowarczyk, Emil Kolasinski, Maciej Stawny, Joanna Kuzminska, Anna Jelinska, Tomasz Goslinski
Summary: Epigallocatechin gallate (EGCG), a polyphenol found in green tea, has potential anticancer and neurodegenerative disease protective effects. However, its bioavailability is limited due to chemical instability and poor absorption, resulting in its current use as a dietary supplement rather than medication.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Food Science & Technology
Meiby Fernandez-Rojas, Lyanne Rodriguez, Andres Trostchansky, Eduardo Fuentes
Summary: Cardiovascular diseases are the leading cause of death worldwide. Platelet hyperactivation can lead to thrombus formation and blood vessel obstruction, while a diet rich in bioactive compounds can help prevent cardiovascular diseases. This review collects the latest research on the cardioprotective and antiplatelet activities of different compounds extracted from natural products.
Article
Hematology
Melissa G. Farb, Lisa Ganley-Leal, Melanie Mott, YanMei Liang, Bahadir Ercan, Michael E. Widlansky, Sherman J. Bigornia, Antonino J. Fiscale, Caroline M. Apovian, Brian Carmine, Donald T. Hess, Joseph A. Vita, Noyan Gokce
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2012)
Article
Hematology
Tinoy J. Kizhakekuttu, Jingli Wang, Kodlipet Dharmashankar, Rong Ying, David D. Gutterman, Joseph A. Vita, Michael E. Widlansky
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2012)
Article
Cardiac & Cardiovascular Systems
Susan Cheng, Na Wang, Martin G. Larson, Joseph N. Palmisano, Gary F. Mitchell, Emelia J. Benjamin, Ramachandran S. Vasan, Daniel Levy, Elizabeth L. McCabe, Joseph A. Vita, Thomas J. Wang, Stanley Y. Shaw, Kenneth S. Cohen, Naomi M. Hamburg
Article
Cardiac & Cardiovascular Systems
George Thanassoulis, Asya Lyass, Emelia J. Benjamin, Martin G. Larson, Joseph A. Vita, Daniel Levy, Naomi M. Hamburg, Michael E. Widlansky, Christopher J. O'Donnell, Gary F. Mitchell, Ramachandran S. Vasan
Article
Cardiac & Cardiovascular Systems
Corey E. Tabit, Sherene M. Shenouda, Monica Holbrook, Jessica L. Fetterman, Soroosh Kiani, Alissa A. Frame, Matthew A. Kluge, Aaron Held, Mustali M. Dohadwala, Noyan Gokce, Melissa G. Farb, James Rosenzweig, Neil Ruderman, Joseph A. Vita, Naomi M. Hamburg
Review
Cardiac & Cardiovascular Systems
Matthew A. Kluge, Jessica L. Fetterman, Joseph A. Vita
CIRCULATION RESEARCH
(2013)
Article
Cardiac & Cardiovascular Systems
Yukio Shimasaki, Ning Pan, Louis M. Messina, Chunying Li, Kai Chen, Lijun Liu, Marcus P. Cooper, Joseph A. Vita, John F. Keaney
CIRCULATION RESEARCH
(2013)
Article
Peripheral Vascular Disease
Justin P. Zachariah, Vanessa Xanthakis, Martin G. Larson, Joseph A. Vita, Lisa M. Sullivan, Holly M. Smith, Radwan Safa, Xuyang Peng, Naomi Hamburg, Daniel Levy, Douglas B. Sawyer, Gary F. Mitchell, Ramachandran S. Vasan
Article
Medicine, General & Internal
Bernhard M. Kaess, Jian Rong, Martin G. Larson, Naomi M. Hamburg, Joseph A. Vita, Daniel Levy, Emelia J. Benjamin, Ramachandran S. Vasan, Gary F. Mitchell
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2012)
Article
Endocrinology & Metabolism
Kathryn A. Britton, Na Wang, Joseph Palmisano, Erin Corsini, Christopher L. Schlett, Udo Hoffmann, Martin G. Larson, Ramachandran S. Vasan, Joseph A. Vita, Gary F. Mitchell, Emelia J. Benjamin, Naomi M. Hamburg, Caroline S. Fox
Article
Endocrinology & Metabolism
Melissa G. Farb, Stephanie Tiwari, Shakun Karki, Doan T. M. Ngo, Brian Carmine, Donald T. Hess, Maria A. Zuriaga, Kenneth Walsh, Jessica L. Fetterman, Naomi M. Hamburg, Joseph A. Vita, Caroline M. Apovian, Noyan Gokce
Article
Peripheral Vascular Disease
Corey E. Tabit, Monica Holbrook, Sherene M. Shenouda, Mustali M. Dohadwala, Michael E. Widlansky, Alissa A. Frame, Brian H. Kim, Mai-Ann Duess, Matthew A. Kluge, Aaron Levit, John F. Keaney, Joseph A. Vita, Naomi M. Hamburg
Article
Peripheral Vascular Disease
Soroosh Kiani, Jonathan G. Aasen, Monika Holbrook, Abhishek Khemka, Farhana Sharmeen, Rebecca M. LeLeiko, Corey E. Tabit Alik Farber, Robert T. Eberhardt, Noyan Gokce, Joseph A. Vita, Naomi M. Hamburg
Editorial Material
Cardiac & Cardiovascular Systems
Joseph A. Vita
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2012)
Editorial Material
Cardiac & Cardiovascular Systems
Joseph A. Vita
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2013)