Synergistic effect of fisetin combined with sorafenib in human cervical cancer HeLa cells through activation of death receptor-5 mediated caspase-8/caspase-3 and the mitochondria-dependent apoptotic pathway

The naturally born fusariotoxin enniatin B and sorafenib exert synergistic activity against cervical cancer in vitro and in vivo

(2015) Rita Dornetshuber-Fleiss et al.   BIOCHEMICAL PHARMACOLOGY

Sorafenib inhibits intracellular signaling pathways and induces cell cycle arrest and cell death in thyroid carcinoma cells irrespective of histological origin or BRAF mutational status

(2015) Martina Broecker-Preuss et al.   BMC CANCER

Mitochondrial apoptosis: killing cancer using the enemy within

(2015) J Lopez et al.   BRITISH JOURNAL OF CANCER

Activation of AMP-activated protein kinase by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib

(2015) Naoki Ishijima et al.   CANCER SCIENCE

Effects of Adjuvant Sorafenib and Sunitinib on Cardiac Function in Renal Cell Carcinoma Patients without Overt Metastases: Results from ASSURE, ECOG 2805

(2015) N. B. Haas et al.   CLINICAL CANCER RESEARCH

Mitochondrial cytochrome c biogenesis: no longer an enigma

(2015) Shalon E. Babbitt et al.   TRENDS IN BIOCHEMICAL SCIENCES

NDRG4 is a novel oncogenic protein and p53 associated regulator of apoptosis in malignant meningioma cells

(2015) Rama P. Kotipatruni et al.   Oncotarget

Delphinidin sensitizes prostate cancer cells to TRAIL-induced apoptosis, by inducing DR5 and causing caspase-mediated HDAC3 cleavage

(2015) Hyeonseok Ko et al.   Oncotarget

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells

(2015) Harish Chandra Pal et al.   Oncotarget

Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance?

(2015) Michelle M. Williams et al.   Oncotarget

Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma

(2015) Harish C. Pal et al.   Oncotarget

Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner

(2015) Irina Kiprianova et al.   NEOPLASIA

RIP Kinase-Mediated Necrosis as an Alternative Mechanisms of Photoreceptor Death

(2015) Yusuke Murakami et al.   Oncotarget

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5

(2015) Jun-jie Chen et al.   Oncotarget

Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression

(2014) Shu-Ching Hsieh et al.   AMINO ACIDS

Involvement of ER stress and activation of apoptotic pathways in fisetin induced cytotoxicity in human melanoma

(2014) Deeba N. Syed et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Synergistic anti-tumor effects of the combination of a benzofuroxan derivate and sorafenib on NCI-H460 human large cell lung carcinoma cells

(2014) Sarah Fernandes Teixeira et al.   BIOMEDICINE & PHARMACOTHERAPY

Fisetin induces apoptosis in human nonsmall lung cancer cells via a mitochondria-mediated pathway

(2014) Kyoung Ah Kang et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Fisetin suppresses ADAM9 expression and inhibits invasion of glioma cancer cells through increased phosphorylation of ERK1/2

(2014) Chien-Min Chen et al.   TUMOR BIOLOGY

The TRAIL of oncogenes to apoptosis

(2013) Eftychia Oikonomou et al.   BIOFACTORS

Quercetin induces cytochrome-c release and ROS accumulation to promote apoptosis and arrest the cell cycle in G2/M, in cervical carcinoma: signal cascade and drug-DNA interaction

(2013) K. Bishayee et al.   CELL PROLIFERATION

Antitumor effect of vascular endothelial growth factor inhibitor sunitinib in preclinical models of hepatocellular carcinoma

(2012) Cedo Martin Bagi et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology Screening Guidelines for the Prevention and Early Detection of Cervical Cancer

(2012) Debbie Saslow et al.   Journal of Lower Genital Tract Disease

Fisetin induces apoptosis in human cervical cancer HeLa cells through ERK1/2-mediated activation of caspase-8-/caspase-3-dependent pathway

(2011) Tsung-Ho Ying et al.   ARCHIVES OF TOXICOLOGY

Cellular and molecular mechanisms of silibinin induces cell-cycle arrest and apoptosis on HeLa cells

(2011) Y. Zhang et al.   CELL BIOCHEMISTRY AND FUNCTION

Anticancer Activity of a Combination of Cisplatin and Fisetin in Embryonal Carcinoma Cells and Xenograft Tumors

(2011) R. Tripathi et al.   MOLECULAR CANCER THERAPEUTICS

Apoptosis by dietary agents for prevention and treatment of prostate cancer

(2009) Naghma Khan et al.   ENDOCRINE-RELATED CANCER

The Prognostic Value of TRAIL and its Death Receptors in Cervical Cancer

(2009) John H. Maduro et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Involvement of the ERK Signaling Pathway in Fisetin Reduces Invasion and Migration in the Human Lung Cancer Cell Line A549

(2009) Yi-Chen Liao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Adverse effects of anticancer agents that target the VEGF pathway

(2009) Helen X. Chen et al.   Nature Reviews Clinical Oncology

Update on novel therapeutic agents for cervical cancer

(2008) Josep Maria del Campo et al.   GYNECOLOGIC ONCOLOGY

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

(2008) Ann-Lii Cheng et al.   LANCET ONCOLOGY

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bcl-2 Protein Family Members: Versatile Regulators of Calcium Signaling in Cell Survival and Apoptosis

(2007) Yiping Rong et al.   Annual Review of Physiology

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY