Genetic polymorphisms in key methotrexate pathway genes are associated with response to treatment in rheumatoid arthritis patients

Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis

(2011) A. Hinks et al.   ANNALS OF THE RHEUMATIC DISEASES

Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate

(2010) Lisa K. Stamp et al.   Pharmacogenetics and Genomics

Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis

(2009) H. Hayashi et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians

(2009) Shruti Sharma et al.   Pharmacogenetics and Genomics

Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate

(2009) Y. C. Lee et al.   RHEUMATOLOGY

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose

(2009) Fumihiko Takeuchi et al.   PLoS Genetics

Pharmacogenetic study of 5,10-methylenetetrahydrofolate reductase C677T and thymidylate synthase 3R/2R gene polymorphisms and methotrexate-related toxicity in Chinese Han patients with inflammatory arthritis

(2008) Q-Y Zeng et al.   ANNALS OF THE RHEUMATIC DISEASES

Can clinical factors at presentation be used to predict outcome of treatment with methotrexate in patients with early inflammatory polyarthritis?

(2008) S L Hider et al.   ANNALS OF THE RHEUMATIC DISEASES

Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research

(2008) C Salliot et al.   ANNALS OF THE RHEUMATIC DISEASES

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose

(2008) G. M. Cooper et al.   BLOOD

Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?

(2008) Yogita Ghodke et al.   CLINICAL RHEUMATOLOGY

Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism

(2008) Petra Bohanec Grabar et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Interaction of genes from influx-metabolism-efflux pathway and their influence on methotrexate efficacy in rheumatoid arthritis patients among Indians

(2008) Shruti Sharma et al.   Pharmacogenetics and Genomics

Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX

(2008) S. L. Hider et al.   RHEUMATOLOGY