Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes

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Defining a New Paradigm for Human Arrhythmia Syndromes

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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Latent Genetic Backgrounds and Molecular Pathogenesis in Drug-Induced Long-QT Syndrome

(2009) Hideki Itoh et al.   Circulation-Arrhythmia and Electrophysiology

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

(2009) Arne Pfeufer et al.   NATURE GENETICS

Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

(2009) Emelia J Benjamin et al.   NATURE GENETICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Genetic variation in the rhythmonome: ethnic variation and haplotype structure in candidate genes for arrhythmias

(2009) William S Bush et al.   PHARMACOGENOMICS

Cellular basis of drug-induced torsades de pointes

(2008) D M Roden   BRITISH JOURNAL OF PHARMACOLOGY

Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia

(2008) S Volpi et al.   MOLECULAR PSYCHIATRY

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE