Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations

Oral Session III-B (OIII-B) Molecular Targets and Genetics in Oncology 9:30 am – 10:30 am

(2011)   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genome-Wide Association Study of Survival in Non–Small Cell Lung Cancer Patients Receiving Platinum-Based Chemotherapy

(2011) Xifeng Wu et al.   JNCI-Journal of the National Cancer Institute

Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers

(2011) Dana Ziliak et al.   Translational Research

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Phase II Study of Paclitaxel, Carboplatin, and Cetuximab as First Line Treatment, for Patients with Advanced Non-small Cell Lung Cancer (NSCLC): Results of OPN-017

(2010) Hossein Borghaei et al.   Journal of Thoracic Oncology

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

High-dose carboplatin-irinotecan-temozolomide: Treatment option for neuroblastoma resistant to topotecan

(2010) Brian H. Kushner et al.   PEDIATRIC BLOOD & CANCER

Population differences in platinum toxicity as a means to identify novel genetic susceptibility variants

(2010) Peter H. OʼDonnell et al.   Pharmacogenetics and Genomics

A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals

(2009) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

SCAN: SNP and copy number annotation

(2009) Eric R. Gamazon et al.   BIOINFORMATICS

Pharmacokinetics of carboplatin and etoposide in infant neuroblastoma patients

(2009) Gareth J. Veal et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Platinum neurotoxicity pharmacogenetics

(2009) S. R. McWhinney et al.   MOLECULAR CANCER THERAPEUTICS

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy

(2009) Colin J D Ross et al.   NATURE GENETICS

Platinum pathway

(2009) Sharon Marsh et al.   Pharmacogenetics and Genomics

Gemcitabine and Arabinosylcytosin Pharmacogenomics: Genome-Wide Association and Drug Response Biomarkers

(2009) Liang Li et al.   PLoS One

Sensitive Detection of Chromosomal Segments of Distinct Ancestry in Admixed Populations

(2009) Alkes L. Price et al.   PLoS Genetics

Genetic Architecture of Transcript-Level Variation in Humans

(2008) Shiwei Duan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity

(2008) C. M. Hartford et al.   BLOOD

Practical aspects of imputation-driven meta-analysis of genome-wide association studies

(2008) P. I.W. de Bakker et al.   HUMAN MOLECULAR GENETICS

Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans

(2008) R. S. Huang et al.   MOLECULAR CANCER THERAPEUTICS