标题
Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation
作者
关键词
-
出版物
PHARMACOGENOMICS
Volume 13, Issue 1, Pages 55-70
出版商
Future Medicine Ltd
发表日期
2011-12-19
DOI
10.2217/pgs.11.121
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pharmocoepigenetics: a new approach to predicting individual drug responses and targeting new drugs
- (2014) Wanda Baer-Dubowska et al. Pharmacological Reports
- Genetic Variation Predicting Cisplatin Cytotoxicity Associated with Overall Survival in Lung Cancer Patients Receiving Platinum-Based Chemotherapy
- (2011) X.-L. Tan et al. CLINICAL CANCER RESEARCH
- Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing
- (2011) M V Relling et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Comprehensive DNA methylation analysis of human peripheral blood leukocytes and lymphoblastoid cell lines
- (2011) Hiroko Sugawara et al. Epigenetics
- The effects of EBV transformation on gene expression levels and methylation profiles
- (2011) Minal Çalışkan et al. HUMAN MOLECULAR GENETICS
- Mycophenolic acid response biomarkers: A cell line model system-based genome-wide screen
- (2011) Tse-Yu Wu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Impact of genetic variation in FKBP5 on clinical response in pediatric acute myeloid leukemia patients: a pilot study
- (2011) A K Mitra et al. LEUKEMIA
- Low dose radiation response curves, networks and pathways in human lymphoblastoid cells exposed from 1 to 10cGy of acute gamma radiation
- (2011) A.J. Wyrobek et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
- (2011) Ingrid E. Wertz et al. NATURE
- Chemotherapeutic-induced apoptosis
- (2011) Yujia Wen et al. Pharmacogenetics and Genomics
- Genome-wide expression profiling of human lymphoblastoid cell lines identifiesCHL1as a putative SSRI antidepressant response biomarker
- (2011) Ayelet Morag et al. PHARMACOGENOMICS
- Genome-Wide Local Ancestry Approach Identifies Genes and Variants Associated with Chemotherapeutic Susceptibility in African Americans
- (2011) Heather E. Wheeler et al. PLoS One
- Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers
- (2011) Dana Ziliak et al. Translational Research
- Genetic Determinants of Lipid Traits in Diverse Populations from the Population Architecture using Genomics and Epidemiology (PAGE) Study
- (2011) Logan Dumitrescu et al. PLoS Genetics
- DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
- (2011) Jordana T Bell et al. GENOME BIOLOGY
- Gene Expression in Skin and Lymphoblastoid Cells: Refined Statistical Method Reveals Extensive Overlap in cis-eQTL Signals
- (2010) Jun Ding et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Versatile Gene-Based Test for Genome-wide Association Studies
- (2010) Jimmy Z. Liu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Combined Influence of LDLR and HMGCR Sequence Variation on Lipid-Lowering Response to Simvastatin
- (2010) Lara M. Mangravite et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- An integrative method for scoring candidate genes from association studies: application to warfarin dosing
- (2010) Nicholas P Tatonetti et al. BMC BIOINFORMATICS
- Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach
- (2010) Krishna R Kalari et al. BMC GENOMICS
- MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: Introducing microRNA pharmacogenomics
- (2010) Prasun J. Mishra et al. CELL CYCLE
- Radiation pharmacogenomics: A genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines
- (2010) N. Niu et al. GENOME RESEARCH
- Genome-Wide Associations and Functional Genomic Studies of Musculoskeletal Adverse Events in Women Receiving Aromatase Inhibitors
- (2010) James N. Ingle et al. JOURNAL OF CLINICAL ONCOLOGY
- A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity
- (2010) S-H Chen et al. LEUKEMIA
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- Systems analysis of EGF receptor signaling dynamics with microwestern arrays
- (2010) Mark F Ciaccio et al. NATURE METHODS
- Ancestry and Disease in the Age of Genomic Medicine
- (2010) Charles N. Rotimi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Population differences in platinum toxicity as a means to identify novel genetic susceptibility variants
- (2010) Peter H. OʼDonnell et al. Pharmacogenetics and Genomics
- Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients
- (2010) Maximilian T. Lobmeyer et al. Pharmacogenetics and Genomics
- Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines
- (2010) A L Stark et al. PHARMACOGENOMICS JOURNAL
- ExprTarget: An Integrative Approach to Predicting Human MicroRNA Targets
- (2010) Eric R. Gamazon et al. PLoS One
- Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci
- (2010) E. R. Gamazon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acetaminophen-NAPQI Hepatotoxicity: A Cell Line Model System Genome-Wide Association Study
- (2010) Ann M. Moyer et al. TOXICOLOGICAL SCIENCES
- Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations
- (2010) Alexandra C. Nica et al. PLoS Genetics
- Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
- (2010) Dan L. Nicolae et al. PLoS Genetics
- SCAN: SNP and copy number annotation
- (2009) Eric R. Gamazon et al. BIOINFORMATICS
- FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt
- (2009) Huadong Pei et al. CANCER CELL
- Cancer Pharmacoethnicity: Ethnic Differences in Susceptibility to the Effects of Chemotherapy
- (2009) P. H. O'Donnell et al. CLINICAL CANCER RESEARCH
- Polymorphism of human cytochrome P450 enzymes and its clinical impact
- (2009) Shu-Feng Zhou et al. DRUG METABOLISM REVIEWS
- Detecting rare variants for complex traits using family and unrelated data
- (2009) Xiaofeng Zhu et al. GENETIC EPIDEMIOLOGY
- Expression quantitative trait loci detected in cell lines are often present in primary tissues
- (2009) Kevin Bullaughey et al. HUMAN MOLECULAR GENETICS
- Human Glucocorticoid Receptor α Gene (NR3C1) Pharmacogenomics: Gene Resequencing and Functional Genomics
- (2009) Nifang Niu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Genetic analysis of radiation-induced changes in human gene expression
- (2009) Denis A. Smirnov et al. NATURE
- Association of thymidylate synthase variants with 5-fluorouracil cytotoxicity
- (2009) Eric J. Peters et al. Pharmacogenetics and Genomics
- Platinum pathway
- (2009) Sharon Marsh et al. Pharmacogenetics and Genomics
- Pharmacogenomic Discovery Using Cell-Based Models
- (2009) M. Welsh et al. PHARMACOLOGICAL REVIEWS
- Genome-Wide Transcriptional Profiling Reveals MicroRNA-Correlated Genes and Biological Processes in Human Lymphoblastoid Cell Lines
- (2009) Liang Wang et al. PLoS One
- Gemcitabine and Arabinosylcytosin Pharmacogenomics: Genome-Wide Association and Drug Response Biomarkers
- (2009) Liang Li et al. PLoS One
- Next generation disparities in human genomics: concerns and remedies
- (2009) Anna C. Need et al. TRENDS IN GENETICS
- Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data
- (2008) Bingshan Li et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia
- (2008) Deborah French et al. BLOOD
- Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity
- (2008) C. M. Hartford et al. BLOOD
- Gemcitabine and Cytosine Arabinoside Cytotoxicity: Association with Lymphoblastoid Cell Expression
- (2008) L. Li et al. CANCER RESEARCH
- Variation in the 3-Hydroxyl-3-Methylglutaryl Coenzyme A Reductase Gene Is Associated With Racial Differences in Low-Density Lipoprotein Cholesterol Response to Simvastatin Treatment
- (2008) Ronald M. Krauss et al. CIRCULATION
- Alternative Splicing of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Is Associated With Plasma Low-Density Lipoprotein Cholesterol Response to Simvastatin
- (2008) Marisa Wong Medina et al. CIRCULATION
- Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis
- (2008) Sunita J. Shukla et al. Pharmacogenetics and Genomics
- Pharmacogenomics of Interferon-ß Therapy in Multiple Sclerosis: Baseline IFN Signature Determines Pharmacological Differences between Patients
- (2008) Lisa G. M. van Baarsen et al. PLoS One
- DNA SEQUENCING: A Plan to Capture Human Diversity in 1000 Genomes
- (2008) J. Kaiser SCIENCE
- Mapping the Genetic Architecture of Gene Expression in Human Liver
- (2008) Eric E Schadt et al. PLOS BIOLOGY
- Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines
- (2008) Edwin Choy et al. PLoS Genetics
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started