Review
Genetics & Heredity
Mercedeh Ghadessi, Junrui Di, Chenkun Wang, Kiichiro Toyoizumi, Nan Shao, Chaoqun Mei, Charmaine Demanuele, Rui (Sammi) Tang, Gianna McMillan, Robert A. Beckman
Summary: Traditional clinical trials face challenges in recruiting rare disease patients due to their limited number and scattered distribution. Decentralized Clinical Trials (DCT) offer a participant-centric approach that utilizes new technologies and innovative procedures to interact with participants at home, improving trial quality.
ORPHANET JOURNAL OF RARE DISEASES
(2023)
Article
Veterinary Sciences
Antonio Sykes, Viola Galligioni, Juan Estefanell, Stuart Hetherington, Marco Brocca, Joao Correia, Andre Ferreira, Eleonora M. Pieroni, Graziano Fiorito
Summary: This article discusses research on cephalopod molluscs and the challenges of captive breeding. The need for specific recommendations on the capture and transport of these animals is highlighted. The authors provide suggestions for standardized assessment methods and a training program.
LABORATORY ANIMALS
(2023)
Article
Computer Science, Information Systems
Keping Yu, Zhiwei Guo, Yu Shen, Wei Wang, Jerry Chun-Wei Lin, Takuro Sato
Summary: The emergence of Artificial Intelligence of Things (AIoT) has provided new opportunities for social computing applications. This article proposes a secure AIoT architecture for implicit group recommendations, which effectively captures group preference features and provides personalized services through hardware and software modules.
IEEE INTERNET OF THINGS JOURNAL
(2022)
Review
Oncology
Evangelos Terpos, Elena Zamagni, Suzanne Lentzsch, Matthew T. Drake, Ramon Garcia-Sanz, Niels Abildgaard, Ioannis Ntanasis-Stathopoulos, Fredrik Schjesvold, Javier de la Rubia, Charalampia Kyriakou, Jens Hillengass, Sonja Zweegman, Michele Cavo, Philippe Moreau, Jesus San-Miguel, Meletios A. Dimopoulos, Nikhil Munshi, Brian G. M. Durie, Noopur Raje
Summary: The Bone Working Group of the International Myeloma Working Group recommends the use of zoledronic acid as the preferred bone-targeted agent for patients with newly diagnosed multiple myeloma. Denosumab can be considered for patients with renal impairment. Cement augmentation is effective for painful vertebral compression fractures.
Article
Computer Science, Information Systems
Kwang Hee Lee, Myoung Ho Kim
Summary: This study proposes a novel Bayesian inductive learning method, called IndiG, for making recommendations to both seen and unseen groups. By incorporating a function distribution and a transductive model as prior and posterior, and utilizing cost-effective regularization, the proposed method outperforms existing methods in group recommendation.
INFORMATION SCIENCES
(2022)
Article
Medical Laboratory Technology
Stephen R. Master, Tony C. Badrick, Andreas Bietenbeck, Shannon Haymond
Summary: Machine learning has great potential for clinical applications in laboratory medicine, but careful control of the development and validation pipelines is necessary to avoid potential pitfalls. To address these challenges, a working group from the International Federation for Clinical Chemistry and Laboratory Medicine has provided consensus recommendations for best practices in this domain.
CLINICAL CHEMISTRY
(2023)
Article
Clinical Neurology
Bruno Dubois, Nicolas Villain, Giovanni B. Frisoni, Gil D. Rabinovici, Marwan Sabbagh, Stefano Cappa, Alexandre Bejanin, Stephanie Bombois, Stephane Epelbaum, Marc Teichmann, Marie-Odile Habert, Agneta Nordberg, Kaj Blennow, Douglas Galasko, Yaakov Stern, Christopher C. Rowe, Stephen Salloway, Lon S. Schneider, Jeffrey L. Cummings, Howard H. Feldman
Summary: The use of biomarkers in the diagnosis of Alzheimer's disease has limitations and should be used cautiously in a clinical setting, restricted to individuals with specific phenotypes and positive biomarkers. Biomarker-positive cognitively unimpaired individuals should be considered at-risk for progression to Alzheimer's disease.
Article
Critical Care Medicine
Brian L. Edlow, Varina L. Boerwinkle, Jitka Annen, Melanie Boly, Olivia Gosseries, Steven Laureys, Pratik Mukherjee, Louis Puybasset, Robert D. Stevens, Zachary D. Threlkeld, Virginia F. J. Newcombe, Davinia Fernandez-Espejo, Curing Coma Campaign
Summary: Advances in neuroimaging have provided insights into the mechanisms causing disorders of consciousness in patients with severe brain injuries. Neuroimaging techniques have improved diagnosis and prognosis, leading to endorsement of fMRI for clinical evaluation. However, standardized reporting is needed for research and collaboration.
NEUROCRITICAL CARE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lorenzo Placidi, Roberta Castriconi, Tiziana Rancati, Michela Lecchi, Franco Fusi, Paolo Russo, Carlo Cavedon, Claudio Fiorino, Cristina Garibaldi
Summary: The survey conducted within the Italian Association of Medical Physics and Health Physics (AIFM) analyzed the number and themes of peer-reviewed articles contributed by AIFM members. The findings provide a quantitative assessment and groundwork for supporting future AIFM strategies, promoting scientific activity of medical physicists, and facilitating rational comparison with other countries, especially in Europe.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2021)
Article
Medical Laboratory Technology
Anja Jokic, Vladimira Rimac, Jelena Vlasic Tanaskovic, Sonja Podolar, Lorena Honovic, Jasna Lenicek Krleza
Summary: The survey results show that Croatian medical biochemistry laboratories are in line with recommendations in terms of critical results reporting and monitoring of postanalytical quality indicators, but there is still a need for harmonization in the management of reference intervals verification, delta check, and reflex/reflective testing.
Article
Biochemical Research Methods
Andrew R. Jones, Eric W. Deutsch, Juan Antonio Vizcaino
Summary: DIA proteomics techniques have made significant progress in recent years, but there is still room for improvement in terms of FAIR data principles. To enhance the current situation for DIA data, recommendations include developing an open data standard for spectral libraries, mandating the availability of spectral libraries in ProteomeXchange resources, improving support for DIA data in data standards, and enhancing support for DIA datasets in ProteomeXchange resources.
Review
Oncology
Philippe Moreau, Shaji K. Kumar, Jesus San Miguel, Faith Davies, Elena Zamagni, Nizar Bahlis, Heinz Ludwig, Joseph Mikhael, Evangelos Terpos, Fredrik Schjesvold, Thomas Martin, Kwee Yong, Brian G. M. Durie, Thierry Facon, Artur Jurczyszyn, Surbhi Sidana, Noopur Raje, Niels van de Donk, Sagar Lonial, Michele Cavo, Sigurdur Y. Kristinsson, Suzanne Lentzsch, Roman Hajek, Kenneth C. Anderson, Cristina Joao, Hermann Einsele, Pieter Sonneveld, Monika Engelhardt, Rafael Fonseca, Annette Vangsted, Katja Weisel, Rachid Baz, Vania Hungria, Jesus G. Berdeja, Fernando Leal da Costa, Angelo Maiolino, Anders Waage, David H. Vesole, Enrique M. Ocio, Hang Quach, Christoph Driessen, Joan Blade, Xavier Leleu, Eloisa Riva, Peter Leif Bergsagel, Jian Hou, Wee Joo Chng, Ulf-Henrik Mellqvist, Dominik Dytfeld, Jean-Luc Harousseau, Hartmut Goldschmidt, Jacob Laubach, Nikhil C. Munshi, Francesca Gay, Meral Beksac, Luciano J. Costa, Martin Kaiser, Parameswaran Hari, Mario Boccadoro, Saad Z. Usmani, Sonja Zweegman, Sarah Holstein, Orhan Sezer, Simon Harrison, Hareth Nahi, Gordon Cook, Maria-Victoria Mateos, S. Vincent Rajkumar, Meletios A. Dimopoulos, Paul G. Richardson
Summary: This policy review presents clinical practice recommendations for the treatment of relapsed and refractory multiple myeloma, integrating drug access issues for patients in different income settings to improve patient outcomes in real-world practice.
Article
Oncology
Fatih Gurler, Demet Dondu Kasim, Bediz Kurt Inci, Osman Sutcuoglu, Oktay Unsal, Volkan Aslan, Gozde Tahtaci, Nuriye Ozdemir, Aytug Uner, Nazan Gunel, Ahmet Ozet, Ozan Yazici
Summary: The survey revealed that a majority of medical oncologists in Turkey have good general knowledge about biosimilars but lack understanding of local approval and reimbursement issues, and most are unwilling to switch from a reference product to a biosimilar. There is a need for more accurate local regulations and education in the biotechnology era.
JOURNAL OF ONCOLOGY PHARMACY PRACTICE
(2022)
Review
Medicine, General & Internal
Maria Eva Mingot-Castellano, Mariana Canaro Hirnyk, Blanca Sanchez-Gonzalez, Maria Teresa Alvarez-Roman, Abelardo Barez-Garcia, Angel Bernardo-Gutierrez, Silvia Bernat-Pablo, Estefania Bolanos-Calderon, Nora Butta-Coll, Gonzalo Caballero-Navarro, Isabel Socorro Caparros-Miranda, Laura Entrena-Urena, Luis Fernando Fernandez-Fuertes, Luis Javier Garcia-Frade, Maria del Carmen Gomez del Castillo, Tomas Jose Gonzalez-Lopez, Carlos Grande-Garcia, Jose Maria Guinea de Castro, Isidro Jarque-Ramos, Reyes Jimenez-Barcenas, Elsa Lopez-Ansoar, Daniel Martinez-Carballeira, Violeta Martinez-Robles, Emilio Monteagudo-Montesinos, Jose Antonio Paramo-Fernandez, Maria del Mar Perera-alvarez, Inmaculada Soto-Ortega, David Valcarcel-Ferreiras, Cristina Pascual-Izquierdo
Summary: Primary immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by dysregulation of the immune system, causing increased platelet destruction and reduced production. The diverse clinical manifestations make personalized diagnosis and management challenging. The Spanish ITP Group (GEPTI) of the Spanish Society of Hematology and Hemotherapy (SEHH) updated the guidelines in 2021 to provide a practical tool for comprehensive management of primary ITP.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Paul Faya, Perceval Sondag, Steven Novick, Dwaine Banton, John W. Seaman Jr, James D. Stamey, Bruno Boulanger
Summary: While the use of Bayesian methods in nonclinical statistics has been growing, it has been embraced far more slowly than in clinical statistics.
PHARMACEUTICAL STATISTICS
(2021)
Article
Pharmacology & Pharmacy
Beat Neuenschwander, Simon Wandel, Satrajit Roychoudhury, Stuart Bailey
PHARMACEUTICAL STATISTICS
(2016)
Article
Mathematical & Computational Biology
Tim Friede, Christian Rover, Simon Wandel, Beat Neuenschwander
BIOMETRICAL JOURNAL
(2017)
Article
Mathematical & Computational Biology
Beat Neuenschwander, Satrajit Roychoudhury, Heinz Schmidli
STATISTICS IN BIOPHARMACEUTICAL RESEARCH
(2016)
Article
Mathematical & Computational Biology
Tim Friede, Christian Roever, Simon Wandel, Beat Neuenschwander
RESEARCH SYNTHESIS METHODS
(2017)
Article
Mathematical & Computational Biology
Beat Neuenschwander, Satrajit Roychoudhury, Michael Branson
STATISTICS IN BIOPHARMACEUTICAL RESEARCH
(2018)
Article
Biology
Heinz Schmidli, Sandro Gsteiger, Satrajit Roychoudhury, Anthony O'Hagan, David Spiegelhalter, Beat Neuenschwander
Article
Medicine, Research & Experimental
Satrajit Roychoudhury, Nicolas Scheuer, Beat Neuenschwander
Article
Pharmacology & Pharmacy
Kert Viele, Scott Berry, Beat Neuenschwander, Billy Amzal, Fang Chen, Nathan Enas, Brian Hobbs, Joseph G. Ibrahim, Nelson Kinnersley, Stacy Lindborg, Sandrine Micallef, Satrajit Roychoudhury, Laura Thompson
PHARMACEUTICAL STATISTICS
(2014)
Article
Health Care Sciences & Services
Heinz Schmidli, Simon Wandel, Beat Neuenschwander
STATISTICAL METHODS IN MEDICAL RESEARCH
(2013)
Article
Biology
Beat Neuenschwander, Sebastian Weber, Heinz Schmidli, Anthony O'Hagan
Article
Mathematical & Computational Biology
Satrajit Roychoudhury, Beat Neuenschwander
STATISTICS IN MEDICINE
(2020)
Editorial Material
Biology
Beat Neuenschwander, Sebastian Weber, Heinz Schmidli, Anthony O'Hagan
Article
Medical Informatics
Beat Neuenschwander, Satrajit Roychoudhury, Simon Wandel, Kannan Natarajan, Emmanuel Zuber
Summary: This study proposes a patient-centric and tangible measure of clinical benefit, which goes beyond traditional statistical measures and facilitates communication among clinicians, patients, and other parties.
THERAPEUTIC INNOVATION & REGULATORY SCIENCE
(2022)
Article
Medicine, Research & Experimental
Simon Wandel, Beat Neuenschwander, Christian Roever, Tim Friede
