Measuring Tissue Back-Pressure - In Vivo Injection Forces During Subcutaneous Injection

Rheological characterization and injection forces of concentrated protein formulations: An alternative predictive model for non-Newtonian solutions

(2014) Andrea Allmendinger et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Subcutaneous administration of rituximab (MabThera) and trastuzumab (Herceptin) using hyaluronidase

(2013) O Shpilberg et al.   BRITISH JOURNAL OF CANCER

Comparative pharmacokinetics of subcutaneous trastuzumab administered via handheld syringe or proprietary single-use injection device in healthy males

(2013) Chris J. Wynne et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Preference for subcutaneous or intravenous administration of trastuzumab in patients with HER2-positive early breast cancer (PrefHer): an open-label randomised study

(2013) Xavier Pivot et al.   LANCET ONCOLOGY

Mechanistic Determinants of Biotherapeutics Absorption Following SC Administration

(2012) Wolfgang F. Richter et al.   AAPS Journal

Development of a Subcutaneous Formulation for Trastuzumab - Nonclinical and Clinical Bridging Approach to the Approved Intravenous Dosing Regimen

(2012) B. Bittner et al.   ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH

The Minipig as Nonrodent Species in Toxicology—Where Are We Now?

(2012) Niels Christian Ganderup et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Comparison of Subcutaneous and Intravenous Administration of Trastuzumab: A Phase I/Ib Trial in Healthy Male Volunteers and Patients With HER2-Positive Breast Cancer

(2012) Chris Wynne et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Characterization of protein rheology and delivery forces for combination products

(2012) Nitin Rathore et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration

(2012) Yanan Zheng et al.   mAbs

Injectability Evaluation: An Open Issue

(2011) Francesco Cilurzo et al.   AAPS PHARMSCITECH

The effect of a new syringe design on the ability of rheumatoid arthritis patients to inject a biological medication

(2011) Ali Sheikhzadeh et al.   APPLIED ERGONOMICS

Tissue Fluid Pressure and Flow during Pneumatic Compression in Lymphedema of Lower Limbs

(2011) Waldemar L Olszewski et al.   Lymphatic Research and Biology

Rheological and syringeability properties of highly concentrated human polyclonal immunoglobulin solutions

(2010) V. Burckbuchler et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

A Smart Interface for Reliable Intradermal Injection and Infusion of High and Low Viscosity Solutions

(2010) Michael Vosseler et al.   PHARMACEUTICAL RESEARCH

Evaluation of performance, safety, subject acceptance, and compliance of a disposable autoinjector for subcutaneous injections in healthy volunteers

(2010) Cecile Berteau   Patient Preference and Adherence

The utility of the minipig as an animal model in regulatory toxicology

(2010) Gerd Bode et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Injectability of biodegradable in situ forming microparticle systems (ISM)

(2008) W. Rungseevijitprapa et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Reversible Self-Association of a Concentrated Monoclonal Antibody Solution Mediated by Fab–Fab Interaction That Impacts Solution Viscosity

(2008) Sonoko Kanai et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Influence of Human Skin Specimens Consisting of Different Skin Layers on the Result of in vitro Permeation Experiments

(2008) A. Henning et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY