Pharmacokinetic and Pharmacodynamic Relationship of AMG 811, An Anti-IFN-γ IgG1 Monoclonal Antibody, in Patients with Systemic Lupus Erythematosus

Reduced levels of CCL2 and CXCL10 in systemic lupus erythematosus patients under treatment with prednisone, mycophenolate mofetil, or hydroxychloroquine, except in a high STAT1 subset

(2014) Paul R Dominguez-Gutierrez et al.   ARTHRITIS RESEARCH & THERAPY

Mechanistic Determinants of Biotherapeutics Absorption Following SC Administration

(2012) Wolfgang F. Richter et al.   AAPS Journal

IFNα and its response proteins, IP-10 and SIGLEC-1, are biomarkers of disease activity in systemic lupus erythematosus

(2012) Thomas Rose et al.   ANNALS OF THE RHEUMATIC DISEASES

Elevated Serum IL-6, IL-8, MCP-1, CRP, and IFN-? Levels in 10- to 11-Year-Old Boys with Increased BMI

(2012) L. Utsal et al.   Hormone Research in Paediatrics

Population Pharmacokinetic Meta-Analysis of Denosumab in Healthy Subjects and Postmenopausal Women with Osteopenia or Osteoporosis

(2011) Liviawati Sutjandra et al.   CLINICAL PHARMACOKINETICS

Theoretical Considerations of Target-Mediated Drug Disposition Models: Simplifications and Approximations

(2011) Peiming Ma   PHARMACEUTICAL RESEARCH

Population Pharmacokinetics of Therapeutic Monoclonal Antibodies

(2010) Nathanael L. Dirks et al.   CLINICAL PHARMACOKINETICS

Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases

(2010) Matthias Hammon et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Population Pharmacokinetic Analysis of Tocilizumab in Patients With Rheumatoid Arthritis

(2010) Nicolas Frey et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Exposure-Response Modeling of Darbepoetin Alfa in Anemic Patients With Chronic Kidney Disease Not Receiving Dialysis

(2010) Sameer Doshi et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Handling Data Below the Limit of Quantification in Mixed Effect Models

(2009) Martin Bergstrand et al.   AAPS Journal

Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: A validation study

(2009) Jason W. Bauer et al.   ARTHRITIS AND RHEUMATISM

Enhanced expression of interferon-inducible protein-10 correlates with disease activity and clinical manifestations in systemic lupus erythematosus

(2009) K. O. Kong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Population Pharmacokinetic Analysis of Panitumumab in Patients With Advanced Solid Tumors

(2009) Peiming Ma et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Selection between Michaelis–Menten and target-mediated drug disposition pharmacokinetic models

(2009) Xiaoyu Yan et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Monoclonal Antibody Pharmacokinetics and Pharmacodynamics

(2008) W Wang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Approximations of the target-mediated drug disposition model and identifiability of model parameters

(2008) Leonid Gibiansky et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Likelihood based approaches to handling data below the quantification limit using NONMEM VI

(2008) Jae Eun Ahn et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS