Quantitative Assessment of Intestinal First-pass Metabolism of Oral Drugs Using Portal-vein Cannulated Rats

Effect of Intestinal First-Pass Hydrolysis on the Oral Bioavailability of an Ester Prodrug of Fexofenadine

(2012) Kayoko Ohura et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

BDDCS Applied to Over 900 Drugs

(2011) Leslie Z. Benet et al.   AAPS Journal

Impact of Intestinal Glucuronidation on the Pharmacokinetics of Raloxifene

(2011) K. Kosaka et al.   DRUG METABOLISM AND DISPOSITION

1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-Acetyltransferase

(2011) Q. Sun et al.   DRUG METABOLISM AND DISPOSITION

Prediction of the Intestinal First-pass Metabolism of CYP3A and UGT Substrates in Humans from in vitro Data

(2011) Haruka Nishimuta et al.   Drug Metabolism and Pharmacokinetics

Quantitative Prediction of Intestinal Glucuronidation of Drugs in Rats Using In Vitro Metabolic Clearance Data

(2011) Takako Furukawa et al.   Drug Metabolism and Pharmacokinetics

Investigation of the Intestinal Permeability and First-Pass Metabolism of Drugs in Cynomolgus Monkeys Using Single-Pass Intestinal Perfusion

(2010) Masayuki Takahashi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Prediction of the Intestinal First-Pass Metabolism of CYP3A Substrates in Humans Using Cynomolgus Monkeys

(2010) H. Nishimuta et al.   DRUG METABOLISM AND DISPOSITION

Quantitative Prediction of Intestinal Metabolism in Humans from a Simplified Intestinal Availability Model and Empirical Scaling Factor

(2010) K. Kadono et al.   DRUG METABOLISM AND DISPOSITION

Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data

(2010) M. Gertz et al.   DRUG METABOLISM AND DISPOSITION

Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: A study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10

(2009) Takashi Mizuma   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Grapefruit Juice-Drug Interaction Studies as a Method to Assess the Extent of Intestinal Availability: Utility and Limitations

(2008) Michael Gertz et al.   CURRENT DRUG METABOLISM